Tumor Suppressor p53-Binding Protein 1

A nuclear and cytoplasmic protein that associates with KINETOCHORES and contains a C-terminal TUDOR DOMAIN. It plays a critical role in the cellular response to DNA DAMAGE and localizes to DOUBLE-STRAND DNA BREAKS. It may also function in M PHASE CELL CYCLE CHECKPOINTS and as an enhancer of TUMOR SUPPRESSOR PROTEIN P53-mediated transcriptional activation.

Year introduced: 2017

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Tree Number(s): D12.776.260.805, D12.776.660.235.850, D12.776.664.235.950

MeSH Unique ID: D000071857

Entry Terms:

• Tumor Suppressor p53 Binding Protein 1
• Tumor Protein p53-Binding Protein, 1
• Tumor Protein p53 Binding Protein, 1
• 53BP1 Protein
• p202 Protein
• TP53BP1 Protein

Previous Indexing:

• Chromosomal Proteins, Non-Histone (2005-2016)
• DNA-Binding Proteins (2005-2016)
• Intracellular Signaling Peptides and Proteins (2005-2016)

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
DNA-Binding Proteins
Tumor Suppressor p53-Binding Protein 1

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Nuclear Proteins
Chromosomal Proteins, Non-Histone
Tumor Suppressor p53-Binding Protein 1

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Nucleoproteins
Chromosomal Proteins, Non-Histone
Tumor Suppressor p53-Binding Protein 1