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lorlatinib [Supplementary Concept]

inhibits both anaplastic lymphoma kinase and c-ros oncogene 1 (ROS1) protein

Date introduced: August 17, 2014

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MeSH Unique ID: C000590786

Registry Number: OSP71S83EU

Heading Mapped to:

Entry Terms:

  • (10R)-7-amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo(4,3-H)(2,5,11)benzoxadiazacyclotetradecine-3-carbonitrile
  • loratinib
  • 7-amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo(4,3-h)(2,5,11)benzoxadiazacyclotetradecine-3-carbonitrile
  • PF-06463922
  • PF06463922
  • Lorbrena

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