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Autoimmune disease
A disorder resulting from loss of function or tissue destruction of an organ or multiple organs, arising from humoral or cellular immune responses of the individual to his own tissue constituents. It may be systemic (e.g., systemic lupus erythematosus), or organ specific, (e.g., thyroiditis). [from NCI]
Splenic manifestation of leukemia
Infiltration and expansion of the white and/or red pulp and sinusoids of the spleen by leukemic cells. [from NCI]
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