U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from PMC

Reduced circulating aldolase concentration

MedGen UID:
868463
•Concept ID:
C4022857
•
Finding
Synonym: Reduced aldolase level
 
HPO: HP:0012545

Definition

Concentration of fructose 1,6-bisphosphate aldolase in the blood circulation below the lower limit of normal. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVReduced circulating aldolase concentration

Recent clinical studies

Etiology

Serum creatine kinase activity is not a reliable marker for muscle damage in conditions associated with low extracellular glutathione concentration.
Gunst JJ, Langlois MR, Delanghe JR, De Buyzere ML, Leroux-Roels GG
Clin Chem 1998 May;44(5):939-43. PMID: 9590365
Studies on the carrier state in X-linked recessive (Duchenne) muscular dystrophy.
Thomson WH, Sweetin JC, Hilditch TE
Clin Chim Acta 1975 Sep 16;63(3):383-94. doi: 10.1016/0009-8981(75)90061-3. PMID: 240524

Diagnosis

Hereditary non-spherocytic haemolytic anaemia due to red blood cell glutathione synthetase deficiency in four unrelated patients from Spain: clinical and molecular studies.
Corrons JL, Alvarez R, Pujades A, Zarza R, Oliva E, Lasheras G, Callis M, Ribes A, Gelbart T, Beutler E
Br J Haematol 2001 Feb;112(2):475-82. doi: 10.1046/j.1365-2141.2001.02526.x. PMID: 11167850
Serum creatine kinase activity is not a reliable marker for muscle damage in conditions associated with low extracellular glutathione concentration.
Gunst JJ, Langlois MR, Delanghe JR, De Buyzere ML, Leroux-Roels GG
Clin Chem 1998 May;44(5):939-43. PMID: 9590365

Therapy

Serum creatine kinase activity is not a reliable marker for muscle damage in conditions associated with low extracellular glutathione concentration.
Gunst JJ, Langlois MR, Delanghe JR, De Buyzere ML, Leroux-Roels GG
Clin Chem 1998 May;44(5):939-43. PMID: 9590365

Clinical prediction guides

Studies on the carrier state in X-linked recessive (Duchenne) muscular dystrophy.
Thomson WH, Sweetin JC, Hilditch TE
Clin Chim Acta 1975 Sep 16;63(3):383-94. doi: 10.1016/0009-8981(75)90061-3. PMID: 240524

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...