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warfarin response - Efficacy

MedGen UID:
880923
•Concept ID:
CN236588
•
Sign or Symptom

Professional guidelines

PubMed

Genotype-guided warfarin therapy: current status.
Tavares LC, Marcatto LR, Santos PCJL
Pharmacogenomics 2018 May;19(7):667-685. Epub 2018 Apr 27 doi: 10.2217/pgs-2017-0207. PMID: 29701078
Genotype-based clinical trials in cardiovascular disease.
Pereira NL, Sargent DJ, Farkouh ME, Rihal CS
Nat Rev Cardiol 2015 Aug;12(8):475-87. Epub 2015 May 5 doi: 10.1038/nrcardio.2015.64. PMID: 25940926Free PMC Article
Implementing genotype-guided antithrombotic therapy.
Seip RL, Duconge J, Ruaño G
Future Cardiol 2010 May;6(3):409-24. doi: 10.2217/fca.10.6. PMID: 20462345Free PMC Article

Recent clinical studies

Etiology

Acalabrutinib with or without obinutuzumab versus chlorambucil and obinutuzmab for treatment-naive chronic lymphocytic leukaemia (ELEVATE TN): a randomised, controlled, phase 3 trial.
Sharman JP, Egyed M, Jurczak W, Skarbnik A, Pagel JM, Flinn IW, Kamdar M, Munir T, Walewska R, Corbett G, Fogliatto LM, Herishanu Y, Banerji V, Coutre S, Follows G, Walker P, Karlsson K, Ghia P, Janssens A, Cymbalista F, Woyach JA, Salles G, Wierda WG, Izumi R, Munugalavadla V, Patel P, Wang MH, Wong S, Byrd JC
Lancet 2020 Apr 18;395(10232):1278-1291. doi: 10.1016/S0140-6736(20)30262-2. PMID: 32305093Free PMC Article
Genotype-guided warfarin therapy: current status.
Tavares LC, Marcatto LR, Santos PCJL
Pharmacogenomics 2018 May;19(7):667-685. Epub 2018 Apr 27 doi: 10.2217/pgs-2017-0207. PMID: 29701078
Applied pharmacogenomics in cardiovascular medicine.
Weeke P, Roden DM
Annu Rev Med 2014;65:81-94. Epub 2013 Oct 2 doi: 10.1146/annurev-med-101712-122545. PMID: 24111889Free PMC Article
Ezetimibe: a review of its metabolism, pharmacokinetics and drug interactions.
Kosoglou T, Statkevich P, Johnson-Levonas AO, Paolini JF, Bergman AJ, Alton KB
Clin Pharmacokinet 2005;44(5):467-94. doi: 10.2165/00003088-200544050-00002. PMID: 15871634
Olanzapine. Pharmacokinetic and pharmacodynamic profile.
Callaghan JT, Bergstrom RF, Ptak LR, Beasley CM
Clin Pharmacokinet 1999 Sep;37(3):177-93. doi: 10.2165/00003088-199937030-00001. PMID: 10511917

Diagnosis

Plasma contact factors as therapeutic targets.
Tillman BF, Gruber A, McCarty OJT, Gailani D
Blood Rev 2018 Nov;32(6):433-448. Epub 2018 Apr 12 doi: 10.1016/j.blre.2018.04.001. PMID: 30075986Free PMC Article
Pharmacogenetics in Cardiovascular Medicine.
Weeke PE
Adv Pharmacol 2018;83:333-360. doi: 10.1016/bs.apha.2018.04.002. PMID: 29801582
Efficacy and safety of rivaroxaban compared with warfarin among elderly patients with nonvalvular atrial fibrillation in the Rivaroxaban Once Daily, Oral, Direct Factor Xa Inhibition Compared With Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation (ROCKET AF).
Halperin JL, Hankey GJ, Wojdyla DM, Piccini JP, Lokhnygina Y, Patel MR, Breithardt G, Singer DE, Becker RC, Hacke W, Paolini JF, Nessel CC, Mahaffey KW, Califf RM, Fox KA; ROCKET AF Steering Committee and Investigators
Circulation 2014 Jul 8;130(2):138-46. Epub 2014 Jun 3 doi: 10.1161/CIRCULATIONAHA.113.005008. PMID: 24895454
Feasibility and safety of uninterrupted rivaroxaban for periprocedural anticoagulation in patients undergoing radiofrequency ablation for atrial fibrillation: results from a multicenter prospective registry.
Lakkireddy D, Reddy YM, Di Biase L, Vallakati A, Mansour MC, Santangeli P, Gangireddy S, Swarup V, Chalhoub F, Atkins D, Bommana S, Verma A, Sanchez JE, Burkhardt JD, Barrett CD, Baheiry S, Ruskin J, Reddy V, Natale A
J Am Coll Cardiol 2014 Mar 18;63(10):982-8. Epub 2014 Jan 8 doi: 10.1016/j.jacc.2013.11.039. PMID: 24412445
Aspects of anticoagulation in children.
Payne JH
Br J Haematol 2010 Aug;150(3):259-77. Epub 2010 May 26 doi: 10.1111/j.1365-2141.2010.08225.x. PMID: 20528873

Therapy

Acalabrutinib with or without obinutuzumab versus chlorambucil and obinutuzmab for treatment-naive chronic lymphocytic leukaemia (ELEVATE TN): a randomised, controlled, phase 3 trial.
Sharman JP, Egyed M, Jurczak W, Skarbnik A, Pagel JM, Flinn IW, Kamdar M, Munir T, Walewska R, Corbett G, Fogliatto LM, Herishanu Y, Banerji V, Coutre S, Follows G, Walker P, Karlsson K, Ghia P, Janssens A, Cymbalista F, Woyach JA, Salles G, Wierda WG, Izumi R, Munugalavadla V, Patel P, Wang MH, Wong S, Byrd JC
Lancet 2020 Apr 18;395(10232):1278-1291. doi: 10.1016/S0140-6736(20)30262-2. PMID: 32305093Free PMC Article
Genotype-guided warfarin therapy: current status.
Tavares LC, Marcatto LR, Santos PCJL
Pharmacogenomics 2018 May;19(7):667-685. Epub 2018 Apr 27 doi: 10.2217/pgs-2017-0207. PMID: 29701078
New anticoagulants.
Bauer KA
Hematology Am Soc Hematol Educ Program 2006:450-6. doi: 10.1182/asheducation-2006.1.450. PMID: 17124098
Capecitabine: a review.
Walko CM, Lindley C
Clin Ther 2005 Jan;27(1):23-44. doi: 10.1016/j.clinthera.2005.01.005. PMID: 15763604
Olanzapine. Pharmacokinetic and pharmacodynamic profile.
Callaghan JT, Bergstrom RF, Ptak LR, Beasley CM
Clin Pharmacokinet 1999 Sep;37(3):177-93. doi: 10.2165/00003088-199937030-00001. PMID: 10511917

Prognosis

Reversing the anticoagulation effects of dabigatran.
Dager WE, Banares L
Hosp Pract (1995) 2017 Apr;45(2):29-38. Epub 2017 Mar 24 doi: 10.1080/21548331.2017.1298389. PMID: 28335637
Use of genetic data to guide therapy in arterial disease.
Ross S, Nejat S, Paré G
J Thromb Haemost 2015 Jun;13 Suppl 1:S281-9. doi: 10.1111/jth.12924. PMID: 26149037
Feasibility and safety of uninterrupted rivaroxaban for periprocedural anticoagulation in patients undergoing radiofrequency ablation for atrial fibrillation: results from a multicenter prospective registry.
Lakkireddy D, Reddy YM, Di Biase L, Vallakati A, Mansour MC, Santangeli P, Gangireddy S, Swarup V, Chalhoub F, Atkins D, Bommana S, Verma A, Sanchez JE, Burkhardt JD, Barrett CD, Baheiry S, Ruskin J, Reddy V, Natale A
J Am Coll Cardiol 2014 Mar 18;63(10):982-8. Epub 2014 Jan 8 doi: 10.1016/j.jacc.2013.11.039. PMID: 24412445
Advantages and limitations of the new anticoagulants.
Schulman S
J Intern Med 2014 Jan;275(1):1-11. Epub 2013 Oct 11 doi: 10.1111/joim.12138. PMID: 24112453
New anticoagulants.
Bauer KA
Hematology Am Soc Hematol Educ Program 2006:450-6. doi: 10.1182/asheducation-2006.1.450. PMID: 17124098

Clinical prediction guides

Acalabrutinib with or without obinutuzumab versus chlorambucil and obinutuzmab for treatment-naive chronic lymphocytic leukaemia (ELEVATE TN): a randomised, controlled, phase 3 trial.
Sharman JP, Egyed M, Jurczak W, Skarbnik A, Pagel JM, Flinn IW, Kamdar M, Munir T, Walewska R, Corbett G, Fogliatto LM, Herishanu Y, Banerji V, Coutre S, Follows G, Walker P, Karlsson K, Ghia P, Janssens A, Cymbalista F, Woyach JA, Salles G, Wierda WG, Izumi R, Munugalavadla V, Patel P, Wang MH, Wong S, Byrd JC
Lancet 2020 Apr 18;395(10232):1278-1291. doi: 10.1016/S0140-6736(20)30262-2. PMID: 32305093Free PMC Article
Evolution of pharmacogenomics.
Somogy A
Proc West Pharmacol Soc 2008;51:1-4. PMID: 19544663
New anticoagulants.
Bauer KA
Hematology Am Soc Hematol Educ Program 2006:450-6. doi: 10.1182/asheducation-2006.1.450. PMID: 17124098
Ezetimibe: a review of its metabolism, pharmacokinetics and drug interactions.
Kosoglou T, Statkevich P, Johnson-Levonas AO, Paolini JF, Bergman AJ, Alton KB
Clin Pharmacokinet 2005;44(5):467-94. doi: 10.2165/00003088-200544050-00002. PMID: 15871634
Olanzapine. Pharmacokinetic and pharmacodynamic profile.
Callaghan JT, Bergstrom RF, Ptak LR, Beasley CM
Clin Pharmacokinet 1999 Sep;37(3):177-93. doi: 10.2165/00003088-199937030-00001. PMID: 10511917

Recent systematic reviews

Efficacy and Safety of Direct Oral Anticoagulants in Patients with Atrial Fibrillation and Liver Disease: a Meta-Analysis and Systematic Review.
Huang ZC, Li CQ, Liu XY, Cao ZC, Jia HY, Dong Y, Liu TL, Sun JJ
Cardiovasc Drugs Ther 2021 Dec;35(6):1205-1215. Epub 2020 Sep 3 doi: 10.1007/s10557-020-07065-y. PMID: 32880804
Real-world comparisons of reduced-dose non-vitamin K antagonist oral anticoagulants versus warfarin in atrial fibrillation: a systematic review and meta-analysis.
Wang X, Fang L, Liu B, Zheng Y, Zeng J
Heart Fail Rev 2020 Nov;25(6):973-983. doi: 10.1007/s10741-019-09887-x. PMID: 31713086
Direct oral anticoagulants versus warfarin for preventing stroke and systemic embolic events among atrial fibrillation patients with chronic kidney disease.
Kimachi M, Furukawa TA, Kimachi K, Goto Y, Fukuma S, Fukuhara S
Cochrane Database Syst Rev 2017 Nov 6;11(11):CD011373. doi: 10.1002/14651858.CD011373.pub2. PMID: 29105079Free PMC Article
Limited dose warfarin throughout pregnancy in patients with mechanical heart valve prosthesis: a meta-analysis.
Hassouna A, Allam H
Interact Cardiovasc Thorac Surg 2014 Jun;18(6):797-806. Epub 2014 Mar 4 doi: 10.1093/icvts/ivu009. PMID: 24595247
The efficacy and safety of oral anticoagulants in warfarin-suitable patients with nonvalvular atrial fibrillation: systematic review and meta-analysis.
Mitchell SA, Simon TA, Raza S, Jakouloff D, Orme ME, Lockhart I, Drost P
Clin Appl Thromb Hemost 2013 Nov-Dec;19(6):619-31. Epub 2013 May 22 doi: 10.1177/1076029613486539. PMID: 23698729

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