Pain in muscle.

Subjective feeling of tiredness characterized by a lack of energy and motivation that persists for six months or longer.

A carcinoma derived from a squamous epithelial cell of the tongue.

A reduction in erythrocytes volume or hemoglobin concentration.

Hemoglobin F (HbF) contains two globin alpha chains and two globin gamma chains. It is the main form of hemoglobin in the fetus during the last seven months of intrauterine development and in the half year of postnatal life. In adults it normally makes up less than one percent of all hemoglobin. This term refers to an increase in HbF above this limit. In beta thalassemia major, it may represent over 90 percent of all hemoglobin, and in beta thalassemia minor it may make up between 0.5 to 4 percent.

Larger than normal size of erythrocytes.

A reduced number of hematopoietic cells present in the bone marrow relative to marrow fat.

Osteopenia is a term to define bone density that is not normal but also not as low as osteoporosis. By definition from the World Health Organization osteopenia is defined by bone densitometry as a T score -1 to -2.5.

A recurrent form of sinusitis.

A reduced number of lymphocytes in the blood.

An abnormally low number of neutrophils in the peripheral blood.

Deficiency of thyroid hormone.

An abnormal reduction in telomere length. Telomeres are non-coding, repetitive sequences of DNA at the ends of the chromosomes of eukaryotic cells which become shorter as cells divide, and when telomere attrition reaches its limit, cell proliferation arrest, senescence, and apoptosis can occur.