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Neutrophilia in presence of infection

MedGen UID:
1707092
•Concept ID:
C5139433
•
Finding
HPO: HP:0410257

Definition

An increased number of neutrophils circulating in the blood during an infection, such as with a bacteria, virus or fungus. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • Neutrophilia in presence of infection

Professional guidelines

PubMed

Diagnosis and management of neutrophilic myeloid neoplasms.
Schwede M, Gotlib J, Shomali W
Clin Adv Hematol Oncol 2021 Jul;19(7):450-459. PMID: 34236344

Recent clinical studies

Etiology

Evaluation of the Levels of Blood Cells, Vitamin D, and Inflammatory Factors in Children with PFAPA Syndrome.
Abbasi E, Mamizadeh N, Seidkhani H, Khoshnood S, Mohamadi J
Clin Lab 2023 Nov 1;69(11) doi: 10.7754/Clin.Lab.2023.230518. PMID: 37948479
Outcomes and Prognostic Factors in a Large Cohort of Hospitalized Cancer Patients With COVID-19.
Nader Marta G, Colombo Bonadio R, Nicole Encinas Sejas O, Watarai G, Mathias Machado MC, Teixeira Frasson L, Motta Venchiarutti Moniz C, de Luca Ito RK, Peixoto D, Oliveira Hoff C, Menegatti Anastacio V, Ribeiro U Jr, Pereira J, Rocha V, Abdala E, Del Pilar Estevez-Diz M, Hoff PM
JCO Glob Oncol 2021 Jun;7:1084-1092. doi: 10.1200/GO.21.00087. PMID: 34228508Free PMC Article
Use of C-reactive protein concentration in evaluation of diskospondylitis in dogs.
Trub SA, Bush WW, Paek M, Cuff DE
J Vet Intern Med 2021 Jan;35(1):209-216. Epub 2020 Dec 14 doi: 10.1111/jvim.15981. PMID: 33319417Free PMC Article
Creation and assessment of a clinical predictive model for candidaemia in patients with candiduria.
Wang K, Hsueh K, Kronen R, Lin C, Salazar AS, Powderly WG, Spec A
Mycoses 2019 Jul;62(7):554-561. Epub 2019 May 22 doi: 10.1111/myc.12917. PMID: 31025417Free PMC Article
Prevalence and predictive features of bacteremic urinary tract infection in emergency department patients.
Bahagon Y, Raveh D, Schlesinger Y, Rudensky B, Yinnon AM
Eur J Clin Microbiol Infect Dis 2007 May;26(5):349-52. doi: 10.1007/s10096-007-0287-3. PMID: 17431694

Diagnosis

A Review of Morphologic Findings in Peripheral Blood Smears of COVID-19 Patients.
Jain PV, Grover A, Nomani L
WMJ 2023 Dec;122(5):357-363. PMID: 38180924
Diagnosis and management of neutrophilic myeloid neoplasms.
Schwede M, Gotlib J, Shomali W
Clin Adv Hematol Oncol 2021 Jul;19(7):450-459. PMID: 34236344
Use of C-reactive protein concentration in evaluation of diskospondylitis in dogs.
Trub SA, Bush WW, Paek M, Cuff DE
J Vet Intern Med 2021 Jan;35(1):209-216. Epub 2020 Dec 14 doi: 10.1111/jvim.15981. PMID: 33319417Free PMC Article
The role of neutrophils in immune dysfunction during severe inflammation.
Leliefeld PH, Wessels CM, Leenen LP, Koenderman L, Pillay J
Crit Care 2016 Mar 23;20:73. doi: 10.1186/s13054-016-1250-4. PMID: 27005275Free PMC Article
T cells and NKT cells in the pathogenesis of asthma.
Meyer EH, DeKruyff RH, Umetsu DT
Annu Rev Med 2008;59:281-92. doi: 10.1146/annurev.med.59.061506.154139. PMID: 17937589

Therapy

Diagnosis and management of neutrophilic myeloid neoplasms.
Schwede M, Gotlib J, Shomali W
Clin Adv Hematol Oncol 2021 Jul;19(7):450-459. PMID: 34236344
The role of neutrophils in immune dysfunction during severe inflammation.
Leliefeld PH, Wessels CM, Leenen LP, Koenderman L, Pillay J
Crit Care 2016 Mar 23;20:73. doi: 10.1186/s13054-016-1250-4. PMID: 27005275Free PMC Article
Methotrexate-induced pneumonitis: heterogeneity of bronchoalveolar lavage and differences between cancer and rheumatoid arthritis.
D'Elia T
Inflamm Allergy Drug Targets 2014 Feb;13(1):25-33. doi: 10.2174/1871528112666131230013059. PMID: 24372368
Occupational neutrophilic asthma.
Leigh R, Hargreave FE
Can Respir J 1999 Mar-Apr;6(2):194-6. doi: 10.1155/1999/858549. PMID: 10322102
Late adult respiratory distress syndrome.
Meduri GU
New Horiz 1993 Nov;1(4):563-77. PMID: 8087576

Prognosis

A Review of Morphologic Findings in Peripheral Blood Smears of COVID-19 Patients.
Jain PV, Grover A, Nomani L
WMJ 2023 Dec;122(5):357-363. PMID: 38180924
Diagnosis and management of neutrophilic myeloid neoplasms.
Schwede M, Gotlib J, Shomali W
Clin Adv Hematol Oncol 2021 Jul;19(7):450-459. PMID: 34236344
Outcomes and Prognostic Factors in a Large Cohort of Hospitalized Cancer Patients With COVID-19.
Nader Marta G, Colombo Bonadio R, Nicole Encinas Sejas O, Watarai G, Mathias Machado MC, Teixeira Frasson L, Motta Venchiarutti Moniz C, de Luca Ito RK, Peixoto D, Oliveira Hoff C, Menegatti Anastacio V, Ribeiro U Jr, Pereira J, Rocha V, Abdala E, Del Pilar Estevez-Diz M, Hoff PM
JCO Glob Oncol 2021 Jun;7:1084-1092. doi: 10.1200/GO.21.00087. PMID: 34228508Free PMC Article
Use of C-reactive protein concentration in evaluation of diskospondylitis in dogs.
Trub SA, Bush WW, Paek M, Cuff DE
J Vet Intern Med 2021 Jan;35(1):209-216. Epub 2020 Dec 14 doi: 10.1111/jvim.15981. PMID: 33319417Free PMC Article
Creation and assessment of a clinical predictive model for candidaemia in patients with candiduria.
Wang K, Hsueh K, Kronen R, Lin C, Salazar AS, Powderly WG, Spec A
Mycoses 2019 Jul;62(7):554-561. Epub 2019 May 22 doi: 10.1111/myc.12917. PMID: 31025417Free PMC Article

Clinical prediction guides

A Review of Morphologic Findings in Peripheral Blood Smears of COVID-19 Patients.
Jain PV, Grover A, Nomani L
WMJ 2023 Dec;122(5):357-363. PMID: 38180924
An Overview on the Epidemiology and Immunology of COVID-19.
Meskini M, Rezghi Rami M, Maroofi P, Ghosh S, Siadat SD, Sheikhpour M
J Infect Public Health 2021 Oct;14(10):1284-1298. Epub 2021 Aug 4 doi: 10.1016/j.jiph.2021.07.021. PMID: 34420903Free PMC Article
Mucosal Eosinophilia and Neutrophilia Are Not Associated With QOL or Olfactory Function in Chronic Rhinosinusitis.
Farrell NF, Mace JC, Sauer DA, Thomas AJ, Geltzeiler M, Detwiller KY, Smith TL
Am J Rhinol Allergy 2021 Sep;35(5):647-655. Epub 2021 Jan 11 doi: 10.1177/1945892420987439. PMID: 33430615Free PMC Article
Use of C-reactive protein concentration in evaluation of diskospondylitis in dogs.
Trub SA, Bush WW, Paek M, Cuff DE
J Vet Intern Med 2021 Jan;35(1):209-216. Epub 2020 Dec 14 doi: 10.1111/jvim.15981. PMID: 33319417Free PMC Article
Creation and assessment of a clinical predictive model for candidaemia in patients with candiduria.
Wang K, Hsueh K, Kronen R, Lin C, Salazar AS, Powderly WG, Spec A
Mycoses 2019 Jul;62(7):554-561. Epub 2019 May 22 doi: 10.1111/myc.12917. PMID: 31025417Free PMC Article

Recent systematic reviews

A Review of Morphologic Findings in Peripheral Blood Smears of COVID-19 Patients.
Jain PV, Grover A, Nomani L
WMJ 2023 Dec;122(5):357-363. PMID: 38180924
Immunity and inflammatory biomarkers in COVID-19: A systematic review.
Iwamura APD, Tavares da Silva MR, Hümmelgen AL, Soeiro Pereira PV, Falcai A, Grumach AS, Goudouris E, Neto AC, Prando C
Rev Med Virol 2021 Jul;31(4):e2199. Epub 2020 Dec 4 doi: 10.1002/rmv.2199. PMID: 34260778

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