From HPO
Focal segmental glomerulosclerosis- MedGen UID:
- 4904
- •Concept ID:
- C0017668
- •
- Disease or Syndrome
Segmental accumulation of scar tissue in individual (but not all) glomeruli.
Hematuria- MedGen UID:
- 5488
- •Concept ID:
- C0018965
- •
- Disease or Syndrome
The presence of blood in the urine. Hematuria may be gross hematuria (visible to the naked eye) or microscopic hematuria (detected by dipstick or microscopic examination of the urine).
Kidney disorder- MedGen UID:
- 9635
- •Concept ID:
- C0022658
- •
- Disease or Syndrome
A nonspecific term referring to disease or damage of the kidneys.
Proteinuria- MedGen UID:
- 10976
- •Concept ID:
- C0033687
- •
- Finding
Increased levels of protein in the urine.
Decreased glomerular filtration rate- MedGen UID:
- 163428
- •Concept ID:
- C0853068
- •
- Finding
An abnormal reduction in the volume of fluid filtered out of plasma through glomerular capillary walls into Bowman's capsules per unit of time.
Chronic kidney disease- MedGen UID:
- 473458
- •Concept ID:
- C1561643
- •
- Disease or Syndrome
Functional anomaly of the kidney persisting for at least three months.
Thickening of the tubular basement membrane- MedGen UID:
- 343407
- •Concept ID:
- C1855682
- •
- Finding
Increase in thickness of the basement membrane of the tubulus of the kidney.
Impaired renal concentrating ability- MedGen UID:
- 395351
- •Concept ID:
- C1859819
- •
- Finding
A defect in the ability to concentrate the urine.
Impaired renal uric acid clearance- MedGen UID:
- 409813
- •Concept ID:
- C1969371
- •
- Finding
A reduction in the ability of the kidneys to remove uric acid from the serum.
Stage 5 chronic kidney disease- MedGen UID:
- 384526
- •Concept ID:
- C2316810
- •
- Disease or Syndrome
A degree of kidney failure severe enough to require dialysis or kidney transplantation for survival characterized by a severe reduction in glomerular filtration rate (less than 15 ml/min/1.73 m2) and other manifestations including increased serum creatinine.
Acute kidney injury- MedGen UID:
- 388570
- •Concept ID:
- C2609414
- •
- Injury or Poisoning
Sudden loss of renal function, as manifested by decreased urine production, and a rise in serum creatinine or blood urea nitrogen concentration (azotemia).
Renal sodium wasting- MedGen UID:
- 440580
- •Concept ID:
- C2748576
- •
- Finding
An abnormally increased sodium concentration in the urine in the presence of hyponatremia.
Hyperechogenic kidneys- MedGen UID:
- 477530
- •Concept ID:
- C3275899
- •
- Finding
An increase in amplitude of waves returned in ultrasonography of the kidney, which is generally displayed as increased brightness of the signal.
Renal dysplasia- MedGen UID:
- 760690
- •Concept ID:
- C3536714
- •
- Congenital Abnormality
The presence of developmental dysplasia of the kidney.
Renal cyst- MedGen UID:
- 854361
- •Concept ID:
- C3887499
- •
- Disease or Syndrome
A fluid filled sac in the kidney.
Decreased urinary uromodulin level- MedGen UID:
- 1841670
- •Concept ID:
- C5826736
- •
- Finding
The concentration of uromodulin (also known as Tamm Horsfall protein) in the urine, normalized for urine concentration, is below the lower limit of normal.
Hypertensive disorder- MedGen UID:
- 6969
- •Concept ID:
- C0020538
- •
- Disease or Syndrome
The presence of chronic increased pressure in the systemic arterial system.
Fetal growth restriction- MedGen UID:
- 4693
- •Concept ID:
- C0015934
- •
- Pathologic Function
An abnormal restriction of fetal growth with fetal weight below the tenth percentile for gestational age.
Small for gestational age- MedGen UID:
- 65920
- •Concept ID:
- C0235991
- •
- Finding
Smaller than normal size according to sex and gestational age related norms, defined as a weight below the 10th percentile for the gestational age.
Short stature- MedGen UID:
- 87607
- •Concept ID:
- C0349588
- •
- Finding
A height below that which is expected according to age and gender norms. Although there is no universally accepted definition of short stature, many refer to "short stature" as height more than 2 standard deviations below the mean for age and gender (or below the 3rd percentile for age and gender dependent norms).
Chronic constipation- MedGen UID:
- 98325
- •Concept ID:
- C0401149
- •
- Sign or Symptom
Constipation for longer than three months with fewer than 3 bowel movements per week, straining, lumpy or hard stools, and a sensation of anorectal obstruction or incomplete defecation.
Episodic vomiting- MedGen UID:
- 333228
- •Concept ID:
- C1838993
- •
- Finding
Paroxysmal, recurrent episodes of vomiting.
Mild global developmental delay- MedGen UID:
- 861405
- •Concept ID:
- C4012968
- •
- Finding
A mild delay in the achievement of motor or mental milestones in the domains of development of a child.
Anemia- MedGen UID:
- 1526
- •Concept ID:
- C0002871
- •
- Disease or Syndrome
A reduction in erythrocytes volume or hemoglobin concentration.
Gout- MedGen UID:
- 42280
- •Concept ID:
- C0018099
- •
- Disease or Syndrome
Recurrent attacks of acute inflammatory arthritis of a joint or set of joints caused by elevated levels of uric acid in the blood which crystallize and are deposited in joints, tendons, and surrounding tissues.
Retrognathia- MedGen UID:
- 19766
- •Concept ID:
- C0035353
- •
- Congenital Abnormality
An abnormality in which the mandible is mislocalised posteriorly.
Leukopenia- MedGen UID:
- 6073
- •Concept ID:
- C0023530
- •
- Disease or Syndrome
An abnormal decreased number of leukocytes in the blood.
Recurrent infections- MedGen UID:
- 65998
- •Concept ID:
- C0239998
- •
- Finding
Increased susceptibility to infections.
Neutropenia- MedGen UID:
- 163121
- •Concept ID:
- C0853697
- •
- Finding
An abnormally low number of neutrophils in the peripheral blood.
Recurrent cutaneous abscess formation- MedGen UID:
- 867572
- •Concept ID:
- C4021957
- •
- Finding
An increased susceptibility to cutaneous abscess formation, as manifested by a medical history of recurrent cutaneous abscesses.
Decreased proportion of CD4-positive helper T cells- MedGen UID:
- 1719772
- •Concept ID:
- C5235140
- •
- Finding
A decreased proportion of circulating CD4-positive helper T cells relative to total T cell count.
Hyperkalemia- MedGen UID:
- 5691
- •Concept ID:
- C0020461
- •
- Finding
An abnormally increased potassium concentration in the blood.
Increased blood urea nitrogen- MedGen UID:
- 760252
- •Concept ID:
- C0151539
- •
- Finding
An increased amount of nitrogen in the form of urea in the blood.
Elevated circulating creatinine concentration- MedGen UID:
- 148579
- •Concept ID:
- C0700225
- •
- Finding
An increased amount of creatinine in the blood.
Hyperuricemia- MedGen UID:
- 149260
- •Concept ID:
- C0740394
- •
- Disease or Syndrome
An abnormally high level of uric acid in the blood.
Elevated circulating parathyroid hormone level- MedGen UID:
- 167805
- •Concept ID:
- C0857973
- •
- Finding
An abnormal increased concentration of parathyroid hormone.
Triangular face- MedGen UID:
- 324383
- •Concept ID:
- C1835884
- •
- Finding
Facial contour, as viewed from the front, triangular in shape, with breadth at the temples and tapering to a narrow chin.
Oligohydramnios- MedGen UID:
- 86974
- •Concept ID:
- C0079924
- •
- Pathologic Function
Diminished amniotic fluid volume in pregnancy.
Abnormal circulating aldosterone concentration- MedGen UID:
- 808216
- •Concept ID:
- C0857898
- •
- Finding
Abnormal circulating renin concentration- MedGen UID:
- 866691
- •Concept ID:
- C4021038
- •
- Finding
A deviation from the normal concentration of renin in the blood, a central hormone in the control of blood pressure and various other physiological functions.
- Abnormality of blood and blood-forming tissues
- Abnormality of head or neck
- Abnormality of metabolism/homeostasis
- Abnormality of prenatal development or birth
- Abnormality of the cardiovascular system
- Abnormality of the digestive system
- Abnormality of the endocrine system
- Abnormality of the genitourinary system
- Abnormality of the immune system
- Abnormality of the musculoskeletal system
- Abnormality of the nervous system
- Growth abnormality