U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Penetrating foot ulcers

MedGen UID:
871321
•Concept ID:
C4025809
•
Disease or Syndrome
HPO: HP:0001026

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • Penetrating foot ulcers

Professional guidelines

PubMed

Diabetic Foot Australia guideline on footwear for people with diabetes.
van Netten JJ, Lazzarini PA, Armstrong DG, Bus SA, Fitridge R, Harding K, Kinnear E, Malone M, Menz HB, Perrin BM, Postema K, Prentice J, Schott KH, Wraight PR
J Foot Ankle Res 2018;11:2. Epub 2018 Jan 15 doi: 10.1186/s13047-017-0244-z. PMID: 29371890Free PMC Article
Diabetic Foot Infections: an Update in Diagnosis and Management.
Grigoropoulou P, Eleftheriadou I, Jude EB, Tentolouris N
Curr Diab Rep 2017 Jan;17(1):3. doi: 10.1007/s11892-017-0831-1. PMID: 28101794
Emerging issues in the diagnosis and management of infections caused by multi-drug-resistant, gram-positive cocci.
Napolitano LM
Surg Infect (Larchmt) 2005;6 Suppl 2:S-5-22. PMID: 23577494

Recent clinical studies

Etiology

Proximal Tibial Cortex Transverse Distraction Facilitating Healing and Limb Salvage in Severe and Recalcitrant Diabetic Foot Ulcers.
Chen Y, Kuang X, Zhou J, Zhen P, Zeng Z, Lin Z, Gao W, He L, Ding Y, Liu G, Qiu S, Qin A, Lu W, Lao S, Zhao J, Hua Q
Clin Orthop Relat Res 2020 Apr;478(4):836-851. doi: 10.1097/CORR.0000000000001075. PMID: 31794478Free PMC Article
Footwear in the causation and prevention of foot ulcers in diabetes mellitus.
Premkumar R, Rajan P, Rima J, Richard J
Natl Med J India 2017 Sep-Oct;30(5):255-261. doi: 10.4103/0970-258X.234391. PMID: 29916424
Diabetic Foot Infections: an Update in Diagnosis and Management.
Grigoropoulou P, Eleftheriadou I, Jude EB, Tentolouris N
Curr Diab Rep 2017 Jan;17(1):3. doi: 10.1007/s11892-017-0831-1. PMID: 28101794
Risk factors for major amputation in hospitalised diabetic foot patients.
Namgoong S, Jung S, Han SK, Jeong SH, Dhong ES, Kim WK
Int Wound J 2016 Mar;13 Suppl 1(Suppl 1):13-9. Epub 2015 Oct 19 doi: 10.1111/iwj.12526. PMID: 26478562Free PMC Article
Cat-transmitted cutaneous lymphatic sporothricosis.
Xavier MH, Teixeira Ade L, Pinto JM, Rodrigues KS, Vilar EG, Souza AC, Pereira GB
Dermatol Online J 2008 Jul 15;14(7):4. PMID: 18718188

Diagnosis

Clindamycin-induced Maculopapular Exanthema with Preferential Involvement of Striae Distensae: A Koebner phenomenon?
Monteagudo B, Cabanillas M, Iriarte P, Ramírez-Santos A, León-Muinos E, González-Vilas D, Suárez-Amor Ó
Acta Dermatovenerol Croat 2018 Apr;26(1):61-63. PMID: 29782303
Diabetic Foot Infections: an Update in Diagnosis and Management.
Grigoropoulou P, Eleftheriadou I, Jude EB, Tentolouris N
Curr Diab Rep 2017 Jan;17(1):3. doi: 10.1007/s11892-017-0831-1. PMID: 28101794
Therapeutic options for diabetic foot infections: a review with an emphasis on tissue penetration characteristics.
Nicolau DP, Stein GE
J Am Podiatr Med Assoc 2010 Jan-Feb;100(1):52-63. doi: 10.7547/1000052. PMID: 20093545
Diabetic foot osteomyelitis.
Hartemann-Heurtier A, Senneville E
Diabetes Metab 2008 Apr;34(2):87-95. Epub 2008 Jan 31 doi: 10.1016/j.diabet.2007.09.005. PMID: 18242114
Emerging issues in the diagnosis and management of infections caused by multi-drug-resistant, gram-positive cocci.
Napolitano LM
Surg Infect (Larchmt) 2005;6 Suppl 2:S-5-22. PMID: 23577494

Therapy

Proximal Tibial Cortex Transverse Distraction Facilitating Healing and Limb Salvage in Severe and Recalcitrant Diabetic Foot Ulcers.
Chen Y, Kuang X, Zhou J, Zhen P, Zeng Z, Lin Z, Gao W, He L, Ding Y, Liu G, Qiu S, Qin A, Lu W, Lao S, Zhao J, Hua Q
Clin Orthop Relat Res 2020 Apr;478(4):836-851. doi: 10.1097/CORR.0000000000001075. PMID: 31794478Free PMC Article
Diabetic Foot Infections: an Update in Diagnosis and Management.
Grigoropoulou P, Eleftheriadou I, Jude EB, Tentolouris N
Curr Diab Rep 2017 Jan;17(1):3. doi: 10.1007/s11892-017-0831-1. PMID: 28101794
Therapeutic options for diabetic foot infections: a review with an emphasis on tissue penetration characteristics.
Nicolau DP, Stein GE
J Am Podiatr Med Assoc 2010 Jan-Feb;100(1):52-63. doi: 10.7547/1000052. PMID: 20093545
Topical phenytoin for wound healing.
Bhatia A, Prakash S
Dermatol Online J 2004 Jul 15;10(1):5. PMID: 15347487
Vancomycin, metronidazole, and tetracyclines.
Ellison MJ
Clin Podiatr Med Surg 1992 Apr;9(2):425-42. PMID: 1586910

Prognosis

Neuropathic diabetic foot ulcers treated with cerium dioxide nanoparticles: A case report.
Kobyliak N, Abenavoli L, Kononenko L, Kyriienko D, Spivak M
Diabetes Metab Syndr 2019 Jan-Feb;13(1):228-234. Epub 2018 Aug 29 doi: 10.1016/j.dsx.2018.08.027. PMID: 30641702
Clindamycin-induced Maculopapular Exanthema with Preferential Involvement of Striae Distensae: A Koebner phenomenon?
Monteagudo B, Cabanillas M, Iriarte P, Ramírez-Santos A, León-Muinos E, González-Vilas D, Suárez-Amor Ó
Acta Dermatovenerol Croat 2018 Apr;26(1):61-63. PMID: 29782303
Cat-transmitted cutaneous lymphatic sporothricosis.
Xavier MH, Teixeira Ade L, Pinto JM, Rodrigues KS, Vilar EG, Souza AC, Pereira GB
Dermatol Online J 2008 Jul 15;14(7):4. PMID: 18718188
Pharmacokinetics and penetration of linezolid into inflamed soft tissue in diabetic foot infections.
Majcher-Peszynska J, Haase G, Sass M, Mundkowski R, Pietsch A, Klammt S, Schareck W, Drewelow B
Eur J Clin Pharmacol 2008 Nov;64(11):1093-100. Epub 2008 Jul 25 doi: 10.1007/s00228-008-0531-5. PMID: 18654767
Diabetic foot osteomyelitis.
Hartemann-Heurtier A, Senneville E
Diabetes Metab 2008 Apr;34(2):87-95. Epub 2008 Jan 31 doi: 10.1016/j.diabet.2007.09.005. PMID: 18242114

Clinical prediction guides

Clindamycin-induced Maculopapular Exanthema with Preferential Involvement of Striae Distensae: A Koebner phenomenon?
Monteagudo B, Cabanillas M, Iriarte P, Ramírez-Santos A, León-Muinos E, González-Vilas D, Suárez-Amor Ó
Acta Dermatovenerol Croat 2018 Apr;26(1):61-63. PMID: 29782303
Risk factors for major amputation in hospitalised diabetic foot patients.
Namgoong S, Jung S, Han SK, Jeong SH, Dhong ES, Kim WK
Int Wound J 2016 Mar;13 Suppl 1(Suppl 1):13-9. Epub 2015 Oct 19 doi: 10.1111/iwj.12526. PMID: 26478562Free PMC Article
A case of fungal keratitis and onychomycosis simultaneously infected by Trichophyton species.
Jin KW, Jeon HS, Hyon JY, Wee WR, Suh W, Shin YJ
BMC Ophthalmol 2014 Jul 11;14:90. doi: 10.1186/1471-2415-14-90. PMID: 25015110Free PMC Article
Pharmacokinetics and penetration of moxifloxacin into infected diabetic foot tissue in a large diabetic patient cohort.
Majcher-Peszynska J, Sass M, Schipper S, Czaika V, Gussmann A, Lobmann R, Mundkowski RG, Luebbert C, Kujath P, Ruf BR, Koch H, Schareck W, Klar E, Drewelow B; Moxifloxacin-DFI Study Group
Eur J Clin Pharmacol 2011 Feb;67(2):135-42. Epub 2010 Sep 25 doi: 10.1007/s00228-010-0903-5. PMID: 20871984
Diabetic foot osteomyelitis.
Hartemann-Heurtier A, Senneville E
Diabetes Metab 2008 Apr;34(2):87-95. Epub 2008 Jan 31 doi: 10.1016/j.diabet.2007.09.005. PMID: 18242114

Recent systematic reviews

Diabetes: foot ulcers and amputations.
Hunt DL
BMJ Clin Evid 2011 Aug 26;2011 PMID: 21871137Free PMC Article
Diabetes: foot ulcers and amputations.
Hunt D
BMJ Clin Evid 2009 Jan 12;2009 PMID: 19445774Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • ClinVar
      Related medical variations
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...