Joint pain.

A subjective feeling of tiredness characterized by a lack of energy and motivation.

Pain in muscle.

A type of of pulmonary hemorrhage that originates from the pulmonary microcirculation, including the alveolar capillaries, arterioles, and venules. It presents with hemoptysis, anemia, diffuse lung infiltration, and acute respiratory failure. The diagnosis is confirmed by the observation of the accumulation of red blood cells, fibrin, or hemosiderin-laden macrophage in the alveolar space on pathologic biopsy. Hemosiderin, a product of hemoglobin degradation, appears at least 48-72 hours after bleeding and is helpful in distinguishing diffuse alveolar hemorrhage from surgical trauma. Mild interstitial thickening, organizing pneumonia, or diffuse alveolar damage can also be seen.

A height below that which is expected according to age and gender norms. Although there is no universally accepted definition of short stature, many refer to "short stature" as height more than 2 standard deviations below the mean for age and gender (or below the 3rd percentile for age and gender dependent norms).

Failure to thrive (FTT) refers to a child whose physical growth is substantially below the norm.

An inflammation of the colon and small intestine. However, most conditions are either categorized as Enteritis (inflammation of the small intestine) or Colitis (inflammation of the large intestine).

Watery voluminous diarrhea resulting from an imbalance between ion and water secretion and absorption.

The enteric villi are atrophic or absent.

Paroxysmal, recurrent episodes of vomiting.

Impaired feeding performance of an infant as manifested by difficulties such as weak and ineffective sucking, brief bursts of sucking, and falling asleep during sucking. There may be difficulties with chewing or maintaining attention.

A reduction in erythrocytes volume or hemoglobin concentration.

Disseminated intravascular coagulation is characterized by the widespread activation of coagulation, which results in the intravascular formation of fibrin and ultimately thrombotic occlusion of small and midsize vessels.

An abnormal reduction in numbers of all blood cell types (red blood cells, white blood cells, and platelets).

A reduction in the number of circulating thrombocytes.

Decreased concentration of fibrinogen in the blood.

Inflammation of the meninges.

Abnormal increased size of the spleen.

Reduced ability of the natural killer cell to function in the adaptive immune response.

Less than normal number of natural killer cells, a type of lymphocyte in the innate immune system with an ability to mediate cytotoxicity and produce cytokines after the ligation of a germline-encoded activation receptor.

A red eruption of the skin.

Body temperature elevated above the normal range.

Reduction in the concentration of albumin in the blood.

Increased concentration of ferritin in the blood circulation.

Periodic (episodic or recurrent) bouts of fever.

An abnormal elevation of the C-reactive protein level in the blood circulation.

Raised, well-circumscribed areas of erythema and edema involving the dermis and epidermis. Urticaria is intensely pruritic, and blanches completely with pressure.