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Mirror movements 2(MRMV2)

MedGen UID:
482719
Concept ID:
C3281089
Disease or Syndrome
Synonym: MRMV2
 
Gene (location): RAD51 (15q15.1)
 
Monarch Initiative: MONDO:0013790
OMIM®: 614508

Authors:

Additional description

From OMIM
Mirror movements are involuntary movements of a side of the body that mirror intentional movements on the opposite side. Mild mirror movements are physiologic in young children and gradually disappear within the first decade of life, likely due to maturation of the motor network. Mirror movements that persist beyond age 10 years represent a rare disorder usually showing autosomal dominant inheritance with incomplete penetrance (summary by Depienne et al., 2012). For a discussion of genetic heterogeneity of mirror movements, see MRMV1 (157600).  http://www.omim.org/entry/614508

Clinical features

From HPO
Bimanual synkinesia
MedGen UID:
473166
Concept ID:
C0454455
Disease or Syndrome
Involuntary movements of one hand that accompany and mirror intentional movements of the opposite hand.

Professional guidelines

PubMed

Chong DST, Pople M, Hardy TJ, Cowan A, Birchley D, Guy A, McCarthy R, Welchman SA
Ann Vasc Surg 2023 Sep;95:184-187. Epub 2023 Apr 17 doi: 10.1016/j.avsg.2023.03.033. PMID: 37075833
Thieme H, Morkisch N, Rietz C, Dohle C, Borgetto B
J Pain 2016 Feb;17(2):167-80. Epub 2015 Nov 6 doi: 10.1016/j.jpain.2015.10.015. PMID: 26552501
McCabe CS, Haigh RC, Blake DR
Curr Pain Headache Rep 2008 Apr;12(2):103-7. doi: 10.1007/s11916-008-0020-7. PMID: 18474189

Recent clinical studies

Etiology

Kundi MK, Spence NJ
Physiother Res Int 2023 Apr;28(2):e1997. Epub 2023 Mar 6 doi: 10.1002/pri.1997. PMID: 36880119
Xie HM, Zhang KX, Wang S, Wang N, Wang N, Li X, Huang LP
Arch Phys Med Rehabil 2022 May;103(5):988-997. Epub 2021 Aug 28 doi: 10.1016/j.apmr.2021.07.810. PMID: 34461084
Zaheer A, Malik AN, Masood T, Fatima S
BMC Neurol 2021 Oct 27;21(1):416. doi: 10.1186/s12883-021-02441-z. PMID: 34706654Free PMC Article
Thieme H, Morkisch N, Mehrholz J, Pohl M, Behrens J, Borgetto B, Dohle C
Cochrane Database Syst Rev 2018 Jul 11;7(7):CD008449. doi: 10.1002/14651858.CD008449.pub3. PMID: 29993119Free PMC Article
Meekums B, Karkou V, Nelson EA
Cochrane Database Syst Rev 2015 Feb 19;2015(2):CD009895. doi: 10.1002/14651858.CD009895.pub2. PMID: 25695871Free PMC Article

Diagnosis

Martineau S, Perrin L, Kerleau H, Rahal A, Marcotte K
Facial Plast Surg Aesthet Med 2024 Mar-Apr;26(2):172-179. Epub 2023 Oct 11 doi: 10.1089/fpsam.2023.0087. PMID: 37819748
Lin J, Li C, Jiang Q, Shang H
Neurology 2023 Jul 11;101(2):e224. Epub 2023 Feb 16 doi: 10.1212/WNL.0000000000207144. PMID: 36797062Free PMC Article
Tarolli CG, Lizarraga KJ
Semin Neurol 2021 Dec;41(6):717-730. Epub 2021 Nov 26 doi: 10.1055/s-0041-1726355. PMID: 34826874
Spak D, Card E
J Holist Nurs 2020 Jun;38(2):186-192. Epub 2019 Aug 31 doi: 10.1177/0898010119871380. PMID: 31475604
Moseley GL
Neurology 2006 Dec 26;67(12):2129-34. Epub 2006 Nov 2 doi: 10.1212/01.wnl.0000249112.56935.32. PMID: 17082465

Therapy

Kundi MK, Spence NJ
Physiother Res Int 2023 Apr;28(2):e1997. Epub 2023 Mar 6 doi: 10.1002/pri.1997. PMID: 36880119
Zhang Y, Xing Y, Li C, Hua Y, Hu J, Wang Y, Ya R, Meng Q, Bai Y
Eur J Neurol 2022 Jan;29(1):358-371. Epub 2021 Oct 5 doi: 10.1111/ene.15122. PMID: 34558762
Xie HM, Zhang KX, Wang S, Wang N, Wang N, Li X, Huang LP
Arch Phys Med Rehabil 2022 May;103(5):988-997. Epub 2021 Aug 28 doi: 10.1016/j.apmr.2021.07.810. PMID: 34461084
Thieme H, Morkisch N, Mehrholz J, Pohl M, Behrens J, Borgetto B, Dohle C
Cochrane Database Syst Rev 2018 Jul 11;7(7):CD008449. doi: 10.1002/14651858.CD008449.pub3. PMID: 29993119Free PMC Article
Coleman ER, Moudgal R, Lang K, Hyacinth HI, Awosika OO, Kissela BM, Feng W
Curr Atheroscler Rep 2017 Nov 7;19(12):59. doi: 10.1007/s11883-017-0686-6. PMID: 29116473Free PMC Article

Prognosis

Kuo HC, Ferre CL, Chin KY, Friel KM, Gordon AM
Dev Med Child Neurol 2023 Feb;65(2):264-273. Epub 2022 Jun 24 doi: 10.1111/dmcn.15322. PMID: 35751166
Spencer-Smith M, Knight JL, Lacaze E; Irc5 Consortium, Depienne C, Lockhart PJ, Richards LJ, Heron D, Leventer RJ, Robinson GA
Dev Med Child Neurol 2020 Jun;62(6):758-762. Epub 2020 Feb 14 doi: 10.1111/dmcn.14486. PMID: 32060908
Tisseyre J, Amarantini D, Chalard A, Marque P, Gasq D, Tallet J
Neuroscience 2018 May 21;379:246-256. Epub 2018 Mar 26 doi: 10.1016/j.neuroscience.2018.03.027. PMID: 29592842
de Beukelaar TT, Alaerts K, Swinnen SP, Wenderoth N
Cortex 2016 Feb;75:180-192. Epub 2015 Dec 25 doi: 10.1016/j.cortex.2015.11.009. PMID: 26800203
Méneret A, Depienne C, Riant F, Trouillard O, Bouteiller D, Cincotta M, Bitoun P, Wickert J, Lagroua I, Westenberger A, Borgheresi A, Doummar D, Romano M, Rossi S, Defebvre L, De Meirleir L, Espay AJ, Fiori S, Klebe S, Quélin C, Rudnik-Schöneborn S, Plessis G, Dale RC, Sklower Brooks S, Dziezyc K, Pollak P, Golmard JL, Vidailhet M, Brice A, Roze E
Neurology 2014 Jun 3;82(22):1999-2002. Epub 2014 May 7 doi: 10.1212/WNL.0000000000000477. PMID: 24808016Free PMC Article

Clinical prediction guides

Kundi MK, Spence NJ
Physiother Res Int 2023 Apr;28(2):e1997. Epub 2023 Mar 6 doi: 10.1002/pri.1997. PMID: 36880119
Rajendram C, Ken-Dror G, Han T, Sharma P
BMJ Mil Health 2022 Apr;168(2):173-177. Epub 2022 Jan 18 doi: 10.1136/bmjmilitary-2021-002018. PMID: 35042760
Xie HM, Zhang KX, Wang S, Wang N, Wang N, Li X, Huang LP
Arch Phys Med Rehabil 2022 May;103(5):988-997. Epub 2021 Aug 28 doi: 10.1016/j.apmr.2021.07.810. PMID: 34461084
Zaheer A, Malik AN, Masood T, Fatima S
BMC Neurol 2021 Oct 27;21(1):416. doi: 10.1186/s12883-021-02441-z. PMID: 34706654Free PMC Article
Thieme H, Mehrholz J, Pohl M, Behrens J, Dohle C
Cochrane Database Syst Rev 2012 Mar 14;2012(3):CD008449. doi: 10.1002/14651858.CD008449.pub2. PMID: 22419334Free PMC Article

Recent systematic reviews

Kundi MK, Spence NJ
Physiother Res Int 2023 Apr;28(2):e1997. Epub 2023 Mar 6 doi: 10.1002/pri.1997. PMID: 36880119
Zhang Y, Xing Y, Li C, Hua Y, Hu J, Wang Y, Ya R, Meng Q, Bai Y
Eur J Neurol 2022 Jan;29(1):358-371. Epub 2021 Oct 5 doi: 10.1111/ene.15122. PMID: 34558762
Xie HM, Zhang KX, Wang S, Wang N, Wang N, Li X, Huang LP
Arch Phys Med Rehabil 2022 May;103(5):988-997. Epub 2021 Aug 28 doi: 10.1016/j.apmr.2021.07.810. PMID: 34461084
Thieme H, Morkisch N, Mehrholz J, Pohl M, Behrens J, Borgetto B, Dohle C
Cochrane Database Syst Rev 2018 Jul 11;7(7):CD008449. doi: 10.1002/14651858.CD008449.pub3. PMID: 29993119Free PMC Article
Meekums B, Karkou V, Nelson EA
Cochrane Database Syst Rev 2015 Feb 19;2015(2):CD009895. doi: 10.1002/14651858.CD009895.pub2. PMID: 25695871Free PMC Article

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