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Inflammatory bowel disease 17(IBD17)

MedGen UID:
436857
Concept ID:
C2677091
Disease or Syndrome
Synonym: IBD17
 
Gene (location): IL23R (1p31.3)
 
Monarch Initiative: MONDO:0012840
OMIM®: 612261

Definition

Any inflammatory bowel disease in which the cause of the disease is a mutation in the IL23R gene. [from MONDO]

Professional guidelines

PubMed

Ramiro S, Nikiphorou E, Sepriano A, Ortolan A, Webers C, Baraliakos X, Landewé RBM, Van den Bosch FE, Boteva B, Bremander A, Carron P, Ciurea A, van Gaalen FA, Géher P, Gensler L, Hermann J, de Hooge M, Husakova M, Kiltz U, López-Medina C, Machado PM, Marzo-Ortega H, Molto A, Navarro-Compán V, Nissen MJ, Pimentel-Santos FM, Poddubnyy D, Proft F, Rudwaleit M, Telkman M, Zhao SS, Ziade N, van der Heijde D
Ann Rheum Dis 2023 Jan;82(1):19-34. Epub 2022 Oct 21 doi: 10.1136/ard-2022-223296. PMID: 36270658
Lacy BE, Pimentel M, Brenner DM, Chey WD, Keefer LA, Long MD, Moshiree B
Am J Gastroenterol 2021 Jan 1;116(1):17-44. doi: 10.14309/ajg.0000000000001036. PMID: 33315591
Salas A, Hernandez-Rocha C, Duijvestein M, Faubion W, McGovern D, Vermeire S, Vetrano S, Vande Casteele N
Nat Rev Gastroenterol Hepatol 2020 Jun;17(6):323-337. Epub 2020 Mar 19 doi: 10.1038/s41575-020-0273-0. PMID: 32203403

Recent clinical studies

Etiology

Nambu R, Warner N, Mulder DJ, Kotlarz D, McGovern DPB, Cho J, Klein C, Snapper SB, Griffiths AM, Iwama I, Muise AM
Clin Gastroenterol Hepatol 2022 Apr;20(4):e653-e663. Epub 2021 Mar 18 doi: 10.1016/j.cgh.2021.03.021. PMID: 33746097Free PMC Article
Tarris G, de Rougemont A, Charkaoui M, Michiels C, Martin L, Belliot G
Viruses 2021 Jan 13;13(1) doi: 10.3390/v13010104. PMID: 33451106Free PMC Article
Yan JB, Luo MM, Chen ZY, He BH
J Immunol Res 2020;2020:8813558. Epub 2020 Dec 15 doi: 10.1155/2020/8813558. PMID: 33381606Free PMC Article
Olafsson S, McIntyre RE, Coorens T, Butler T, Jung H, Robinson PS, Lee-Six H, Sanders MA, Arestang K, Dawson C, Tripathi M, Strongili K, Hooks Y, Stratton MR, Parkes M, Martincorena I, Raine T, Campbell PJ, Anderson CA
Cell 2020 Aug 6;182(3):672-684.e11. Epub 2020 Jul 21 doi: 10.1016/j.cell.2020.06.036. PMID: 32697969Free PMC Article
Wallace KL, Zheng LB, Kanazawa Y, Shih DQ
World J Gastroenterol 2014 Jan 7;20(1):6-21. doi: 10.3748/wjg.v20.i1.6. PMID: 24415853Free PMC Article

Diagnosis

Vuyyuru SK, Shackelton LM, Hanzel J, Ma C, Jairath V, Feagan BG
Drugs 2023 Jul;83(10):873-891. Epub 2023 Jun 2 doi: 10.1007/s40265-023-01882-9. PMID: 37266801
Gordon H, Biancone L, Fiorino G, Katsanos KH, Kopylov U, Al Sulais E, Axelrad JE, Balendran K, Burisch J, de Ridder L, Derikx L, Ellul P, Greuter T, Iacucci M, Di Jiang C, Kapizioni C, Karmiris K, Kirchgesner J, Laharie D, Lobatón T, Molnár T, Noor NM, Rao R, Saibeni S, Scharl M, Vavricka SR, Raine T
J Crohns Colitis 2023 Jun 16;17(6):827-854. doi: 10.1093/ecco-jcc/jjac187. PMID: 36528797
Li DF, Yang MF, Xu J, Xu HM, Zhu MZ, Liang YJ, Zhang Y, Tian CM, Nie YQ, Shi RY, Wang LS, Yao J
Int J Nanomedicine 2022;17:3893-3911. Epub 2022 Sep 5 doi: 10.2147/IJN.S370784. PMID: 36092245Free PMC Article
Tarris G, de Rougemont A, Charkaoui M, Michiels C, Martin L, Belliot G
Viruses 2021 Jan 13;13(1) doi: 10.3390/v13010104. PMID: 33451106Free PMC Article
Lavelle A, Sokol H
Nat Rev Gastroenterol Hepatol 2020 Apr;17(4):223-237. Epub 2020 Feb 19 doi: 10.1038/s41575-019-0258-z. PMID: 32076145

Therapy

Herrlinger KR, Stange EF
Expert Rev Gastroenterol Hepatol 2023 Jul-Dec;17(8):753-767. Epub 2023 Jul 26 doi: 10.1080/17474124.2023.2240699. PMID: 37480322
Narula N, Chang NH, Mohammad D, Wong ECL, Ananthakrishnan AN, Chan SSM, Carbonnel F, Meyer A
Clin Gastroenterol Hepatol 2023 Sep;21(10):2483-2495.e1. Epub 2023 Jan 31 doi: 10.1016/j.cgh.2023.01.012. PMID: 36731590
Buie MJ, Quan J, Windsor JW, Coward S, Hansen TM, King JA, Kotze PG, Gearry RB, Ng SC, Mak JWY, Abreu MT, Rubin DT, Bernstein CN, Banerjee R, Yamamoto-Furusho JK, Panaccione R, Seow CH, Ma C, Underwood FE, Ahuja V, Panaccione N, Shaheen AA, Holroyd-Leduc J, Kaplan GG; Global IBD Visualization of Epidemiology Studies in the 21st Century (GIVES-21) Research Group, Balderramo D, Chong VH, Juliao-Baños F, Dutta U, Simadibrata M, Kaibullayeva J, Sun Y, Hilmi I, Raja Ali RA, Paudel MS, Altuwaijri M, Hartono JL, Wei SC, Limsrivilai J, El Ouali S, Vergara BI, Dao VH, Kelly P, Hodges P, Miao Y, Li M
Clin Gastroenterol Hepatol 2023 Aug;21(9):2211-2221. Epub 2022 Jul 19 doi: 10.1016/j.cgh.2022.06.030. PMID: 35863682
Salas A, Hernandez-Rocha C, Duijvestein M, Faubion W, McGovern D, Vermeire S, Vetrano S, Vande Casteele N
Nat Rev Gastroenterol Hepatol 2020 Jun;17(6):323-337. Epub 2020 Mar 19 doi: 10.1038/s41575-020-0273-0. PMID: 32203403
Lavelle A, Sokol H
Nat Rev Gastroenterol Hepatol 2020 Apr;17(4):223-237. Epub 2020 Feb 19 doi: 10.1038/s41575-019-0258-z. PMID: 32076145

Prognosis

Buie MJ, Quan J, Windsor JW, Coward S, Hansen TM, King JA, Kotze PG, Gearry RB, Ng SC, Mak JWY, Abreu MT, Rubin DT, Bernstein CN, Banerjee R, Yamamoto-Furusho JK, Panaccione R, Seow CH, Ma C, Underwood FE, Ahuja V, Panaccione N, Shaheen AA, Holroyd-Leduc J, Kaplan GG; Global IBD Visualization of Epidemiology Studies in the 21st Century (GIVES-21) Research Group, Balderramo D, Chong VH, Juliao-Baños F, Dutta U, Simadibrata M, Kaibullayeva J, Sun Y, Hilmi I, Raja Ali RA, Paudel MS, Altuwaijri M, Hartono JL, Wei SC, Limsrivilai J, El Ouali S, Vergara BI, Dao VH, Kelly P, Hodges P, Miao Y, Li M
Clin Gastroenterol Hepatol 2023 Aug;21(9):2211-2221. Epub 2022 Jul 19 doi: 10.1016/j.cgh.2022.06.030. PMID: 35863682
Nambu R, Warner N, Mulder DJ, Kotlarz D, McGovern DPB, Cho J, Klein C, Snapper SB, Griffiths AM, Iwama I, Muise AM
Clin Gastroenterol Hepatol 2022 Apr;20(4):e653-e663. Epub 2021 Mar 18 doi: 10.1016/j.cgh.2021.03.021. PMID: 33746097Free PMC Article
Loftus EV Jr, Feagan BG, Panaccione R, Colombel JF, Sandborn WJ, Sands BE, Danese S, D'Haens G, Rubin DT, Shafran I, Parfionovas A, Rogers R, Lirio RA, Vermeire S
Aliment Pharmacol Ther 2020 Oct;52(8):1353-1365. Epub 2020 Sep 2 doi: 10.1111/apt.16060. PMID: 32876349Free PMC Article
Fu Y, Lee CH, Chi CC
JAMA Dermatol 2018 Dec 1;154(12):1417-1423. doi: 10.1001/jamadermatol.2018.3631. PMID: 30422277Free PMC Article
Ng SC, Shi HY, Hamidi N, Underwood FE, Tang W, Benchimol EI, Panaccione R, Ghosh S, Wu JCY, Chan FKL, Sung JJY, Kaplan GG
Lancet 2017 Dec 23;390(10114):2769-2778. Epub 2017 Oct 16 doi: 10.1016/S0140-6736(17)32448-0. PMID: 29050646

Clinical prediction guides

Vuyyuru SK, Shackelton LM, Hanzel J, Ma C, Jairath V, Feagan BG
Drugs 2023 Jul;83(10):873-891. Epub 2023 Jun 2 doi: 10.1007/s40265-023-01882-9. PMID: 37266801
Olafsson S, McIntyre RE, Coorens T, Butler T, Jung H, Robinson PS, Lee-Six H, Sanders MA, Arestang K, Dawson C, Tripathi M, Strongili K, Hooks Y, Stratton MR, Parkes M, Martincorena I, Raine T, Campbell PJ, Anderson CA
Cell 2020 Aug 6;182(3):672-684.e11. Epub 2020 Jul 21 doi: 10.1016/j.cell.2020.06.036. PMID: 32697969Free PMC Article
Fragoulis GE, Liava C, Daoussis D, Akriviadis E, Garyfallos A, Dimitroulas T
World J Gastroenterol 2019 May 14;25(18):2162-2176. doi: 10.3748/wjg.v25.i18.2162. PMID: 31143068Free PMC Article
Moschen AR, Tilg H, Raine T
Nat Rev Gastroenterol Hepatol 2019 Mar;16(3):185-196. doi: 10.1038/s41575-018-0084-8. PMID: 30478416
Ng SC, Shi HY, Hamidi N, Underwood FE, Tang W, Benchimol EI, Panaccione R, Ghosh S, Wu JCY, Chan FKL, Sung JJY, Kaplan GG
Lancet 2017 Dec 23;390(10114):2769-2778. Epub 2017 Oct 16 doi: 10.1016/S0140-6736(17)32448-0. PMID: 29050646

Recent systematic reviews

Narula N, Chang NH, Mohammad D, Wong ECL, Ananthakrishnan AN, Chan SSM, Carbonnel F, Meyer A
Clin Gastroenterol Hepatol 2023 Sep;21(10):2483-2495.e1. Epub 2023 Jan 31 doi: 10.1016/j.cgh.2023.01.012. PMID: 36731590
Buie MJ, Quan J, Windsor JW, Coward S, Hansen TM, King JA, Kotze PG, Gearry RB, Ng SC, Mak JWY, Abreu MT, Rubin DT, Bernstein CN, Banerjee R, Yamamoto-Furusho JK, Panaccione R, Seow CH, Ma C, Underwood FE, Ahuja V, Panaccione N, Shaheen AA, Holroyd-Leduc J, Kaplan GG; Global IBD Visualization of Epidemiology Studies in the 21st Century (GIVES-21) Research Group, Balderramo D, Chong VH, Juliao-Baños F, Dutta U, Simadibrata M, Kaibullayeva J, Sun Y, Hilmi I, Raja Ali RA, Paudel MS, Altuwaijri M, Hartono JL, Wei SC, Limsrivilai J, El Ouali S, Vergara BI, Dao VH, Kelly P, Hodges P, Miao Y, Li M
Clin Gastroenterol Hepatol 2023 Aug;21(9):2211-2221. Epub 2022 Jul 19 doi: 10.1016/j.cgh.2022.06.030. PMID: 35863682
Nambu R, Warner N, Mulder DJ, Kotlarz D, McGovern DPB, Cho J, Klein C, Snapper SB, Griffiths AM, Iwama I, Muise AM
Clin Gastroenterol Hepatol 2022 Apr;20(4):e653-e663. Epub 2021 Mar 18 doi: 10.1016/j.cgh.2021.03.021. PMID: 33746097Free PMC Article
Barberio B, Zamani M, Black CJ, Savarino EV, Ford AC
Lancet Gastroenterol Hepatol 2021 May;6(5):359-370. Epub 2021 Mar 12 doi: 10.1016/S2468-1253(21)00014-5. PMID: 33721557
Ng SC, Shi HY, Hamidi N, Underwood FE, Tang W, Benchimol EI, Panaccione R, Ghosh S, Wu JCY, Chan FKL, Sung JJY, Kaplan GG
Lancet 2017 Dec 23;390(10114):2769-2778. Epub 2017 Oct 16 doi: 10.1016/S0140-6736(17)32448-0. PMID: 29050646

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