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Aldosterone to renin ratio, increased

MedGen UID:
377644
Concept ID:
C1852324
Finding
Synonyms: ALDOSTERONE TO RENIN RATIO, INCREASED; Increased aldosterone:renin ratio
 
OMIM®: 124080

Professional guidelines

PubMed

Funder J
Trends Cardiovasc Med 2022 May;32(4):228-233. Epub 2021 Mar 26 doi: 10.1016/j.tcm.2021.03.005. PMID: 33775861
Scott G, Gillon TE, Pels A, von Dadelszen P, Magee LA
Am J Obstet Gynecol 2022 Feb;226(2S):S1222-S1236. Epub 2020 Aug 20 doi: 10.1016/j.ajog.2020.08.018. PMID: 32828743
Assadi F
Iran J Kidney Dis 2008 Jul;2(3):115-22. PMID: 19377223

Recent clinical studies

Etiology

Caprio M, Moriconi E, Camajani E, Feraco A, Marzolla V, Vitiello L, Proietti S, Armani A, Gorini S, Mammi C, Egeo G, Aurilia C, Fiorentini G, Tomino C, Barbanti P
J Transl Med 2023 Oct 4;21(1):692. doi: 10.1186/s12967-023-04561-1. PMID: 37794395Free PMC Article
Neuen BL, Oshima M, Agarwal R, Arnott C, Cherney DZ, Edwards R, Langkilde AM, Mahaffey KW, McGuire DK, Neal B, Perkovic V, Pong A, Sabatine MS, Raz I, Toyama T, Wanner C, Wheeler DC, Wiviott SD, Zinman B, Heerspink HJL
Circulation 2022 May 10;145(19):1460-1470. Epub 2022 Apr 8 doi: 10.1161/CIRCULATIONAHA.121.057736. PMID: 35394821
Funder J
Trends Cardiovasc Med 2022 May;32(4):228-233. Epub 2021 Mar 26 doi: 10.1016/j.tcm.2021.03.005. PMID: 33775861
Puglisi S, Rossini A, Poli R, Dughera F, Pia A, Terzolo M, Reimondo G
Front Endocrinol (Lausanne) 2021;12:738848. Epub 2021 Oct 21 doi: 10.3389/fendo.2021.738848. PMID: 34745006Free PMC Article
Nanba K, Vaidya A, Williams GH, Zheng I, Else T, Rainey WE
Circulation 2017 Jul 25;136(4):347-355. Epub 2017 May 31 doi: 10.1161/CIRCULATIONAHA.117.028201. PMID: 28566337Free PMC Article

Diagnosis

Chertow GM, Correa-Rotter R, Vart P, Jongs N, McMurray JJV, Rossing P, Langkilde AM, Sjöström CD, Toto RD, Wheeler DC, Heerspink HJL; DAPA‐CKD Trial Committees and Investigators
J Am Heart Assoc 2023 May 2;12(9):e028739. Epub 2023 Apr 29 doi: 10.1161/JAHA.122.028739. PMID: 37119064Free PMC Article
Funder J
Trends Cardiovasc Med 2022 May;32(4):228-233. Epub 2021 Mar 26 doi: 10.1016/j.tcm.2021.03.005. PMID: 33775861
Albasri A, Hattle M, Koshiaris C, Dunnigan A, Paxton B, Fox SE, Smith M, Archer L, Levis B, Payne RA, Riley RD, Roberts N, Snell KIE, Lay-Flurrie S, Usher-Smith J, Stevens R, Hobbs FDR, McManus RJ, Sheppard JP; STRATIFY investigators
BMJ 2021 Feb 10;372:n189. doi: 10.1136/bmj.n189. PMID: 33568342Free PMC Article
Mustafa QU, Haroon ZH, Ijaz A, Sajid MT, Ayyub M
J Coll Physicians Surg Pak 2017 Mar;27(3):S30-S32. PMID: 28302238
Assadi F
Iran J Kidney Dis 2008 Jul;2(3):115-22. PMID: 19377223

Therapy

Laffin LJ, Rodman D, Luther JM, Vaidya A, Weir MR, Rajicic N, Slingsby BT, Nissen SE; Target-HTN Investigators
JAMA 2023 Sep 26;330(12):1140-1150. doi: 10.1001/jama.2023.16029. PMID: 37690061Free PMC Article
Agarwal R, Sinha AD, Cramer AE, Balmes-Fenwick M, Dickinson JH, Ouyang F, Tu W
N Engl J Med 2021 Dec 30;385(27):2507-2519. Epub 2021 Nov 5 doi: 10.1056/NEJMoa2110730. PMID: 34739197Free PMC Article
Albasri A, Hattle M, Koshiaris C, Dunnigan A, Paxton B, Fox SE, Smith M, Archer L, Levis B, Payne RA, Riley RD, Roberts N, Snell KIE, Lay-Flurrie S, Usher-Smith J, Stevens R, Hobbs FDR, McManus RJ, Sheppard JP; STRATIFY investigators
BMJ 2021 Feb 10;372:n189. doi: 10.1136/bmj.n189. PMID: 33568342Free PMC Article
Chung EY, Ruospo M, Natale P, Bolignano D, Navaneethan SD, Palmer SC, Strippoli GF
Cochrane Database Syst Rev 2020 Oct 27;10(10):CD007004. doi: 10.1002/14651858.CD007004.pub4. PMID: 33107592Free PMC Article
Assadi F
Iran J Kidney Dis 2008 Jul;2(3):115-22. PMID: 19377223

Prognosis

Mustafa QU, Haroon ZH, Ijaz A, Sajid MT, Ayyub M
J Coll Physicians Surg Pak 2017 Mar;27(3):S30-S32. PMID: 28302238
Bhandari S, Ives N, Brettell EA, Valente M, Cockwell P, Topham PS, Cleland JG, Khwaja A, El Nahas M
Nephrol Dial Transplant 2016 Feb;31(2):255-61. Epub 2015 Sep 30 doi: 10.1093/ndt/gfv346. PMID: 26429974Free PMC Article
Arnaldi G, Masini AM, Giacchetti G, Taccaliti A, Faloia E, Mantero F
Braz J Med Biol Res 2000 Oct;33(10):1177-89. doi: 10.1590/s0100-879x2000001000007. PMID: 11004718
Popow C, Pollak A, Herkner K, Scheibenreiter S, Swoboda W
Acta Paediatr Scand 1988 Jan;77(1):136-41. doi: 10.1111/j.1651-2227.1988.tb10612.x. PMID: 2967023
Dillon MJ
Eur J Clin Pharmacol 1980 Jul;18(1):105-8. doi: 10.1007/BF00561486. PMID: 6249611

Clinical prediction guides

Caprio M, Moriconi E, Camajani E, Feraco A, Marzolla V, Vitiello L, Proietti S, Armani A, Gorini S, Mammi C, Egeo G, Aurilia C, Fiorentini G, Tomino C, Barbanti P
J Transl Med 2023 Oct 4;21(1):692. doi: 10.1186/s12967-023-04561-1. PMID: 37794395Free PMC Article
Laffin LJ, Rodman D, Luther JM, Vaidya A, Weir MR, Rajicic N, Slingsby BT, Nissen SE; Target-HTN Investigators
JAMA 2023 Sep 26;330(12):1140-1150. doi: 10.1001/jama.2023.16029. PMID: 37690061Free PMC Article
Chertow GM, Correa-Rotter R, Vart P, Jongs N, McMurray JJV, Rossing P, Langkilde AM, Sjöström CD, Toto RD, Wheeler DC, Heerspink HJL; DAPA‐CKD Trial Committees and Investigators
J Am Heart Assoc 2023 May 2;12(9):e028739. Epub 2023 Apr 29 doi: 10.1161/JAHA.122.028739. PMID: 37119064Free PMC Article
Neuen BL, Oshima M, Agarwal R, Arnott C, Cherney DZ, Edwards R, Langkilde AM, Mahaffey KW, McGuire DK, Neal B, Perkovic V, Pong A, Sabatine MS, Raz I, Toyama T, Wanner C, Wheeler DC, Wiviott SD, Zinman B, Heerspink HJL
Circulation 2022 May 10;145(19):1460-1470. Epub 2022 Apr 8 doi: 10.1161/CIRCULATIONAHA.121.057736. PMID: 35394821
Scott G, Gillon TE, Pels A, von Dadelszen P, Magee LA
Am J Obstet Gynecol 2022 Feb;226(2S):S1222-S1236. Epub 2020 Aug 20 doi: 10.1016/j.ajog.2020.08.018. PMID: 32828743

Recent systematic reviews

Zhou W, Yang X, Jin J, Cheng M, Li Y, Bai Y, Xu J
Int Urol Nephrol 2024 Jan;56(1):181-190. Epub 2023 May 17 doi: 10.1007/s11255-023-03599-w. PMID: 37195574
Scott G, Gillon TE, Pels A, von Dadelszen P, Magee LA
Am J Obstet Gynecol 2022 Feb;226(2S):S1222-S1236. Epub 2020 Aug 20 doi: 10.1016/j.ajog.2020.08.018. PMID: 32828743
Albasri A, Hattle M, Koshiaris C, Dunnigan A, Paxton B, Fox SE, Smith M, Archer L, Levis B, Payne RA, Riley RD, Roberts N, Snell KIE, Lay-Flurrie S, Usher-Smith J, Stevens R, Hobbs FDR, McManus RJ, Sheppard JP; STRATIFY investigators
BMJ 2021 Feb 10;372:n189. doi: 10.1136/bmj.n189. PMID: 33568342Free PMC Article
Chung EY, Ruospo M, Natale P, Bolignano D, Navaneethan SD, Palmer SC, Strippoli GF
Cochrane Database Syst Rev 2020 Oct 27;10(10):CD007004. doi: 10.1002/14651858.CD007004.pub4. PMID: 33107592Free PMC Article
Silver SA, Bell CM, Chertow GM, Shah PS, Shojania K, Wald R, Harel Z
Clin J Am Soc Nephrol 2017 Oct 6;12(10):1601-1614. Epub 2017 Sep 6 doi: 10.2215/CJN.02490317. PMID: 28877926Free PMC Article

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