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Difficulty walking

MedGen UID:
86319
•Concept ID:
C0311394
•
Finding
Synonyms: Ambulation Difficulties; Ambulation Difficulty; Ambulatory Difficulties; Ambulatory Difficulty; Difficulties, Ambulation; Difficulties, Ambulatory; Difficulty Ambulation; Difficulty Walking; Difficulty, Ambulation; Walking, Difficulty
SNOMED CT: Difficulty walking (719232003)

Definition

Any persistent problem with walking. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDifficulty walking

Professional guidelines

PubMed

Eteplirsen Treatment for Duchenne Muscular Dystrophy: A Qualitative Patient Experience Study.
Iff J, Carmichael C, McKee S, Sehinovych I, McNeill C, Tesi-Rocha C, Henricson E, Muntoni F, Kitchen H
Adv Ther 2024 Aug;41(8):3278-3298. Epub 2024 Jul 3 doi: 10.1007/s12325-024-02915-9. PMID: 38958840Free PMC Article
Disease course and treatment patterns in progressive supranuclear palsy: A real-world study.
Morgan JC, Ye X, Mellor JA, Golden KJ, Zamudio J, Chiodo LA, Bao Y, Xie T
J Neurol Sci 2021 Feb 15;421:117293. Epub 2020 Dec 25 doi: 10.1016/j.jns.2020.117293. PMID: 33385754
A 6-Week Web-Based Osteoarthritis Treatment Program: Observational Quasi-Experimental Study.
Nero H, Dahlberg J, Dahlberg LE
J Med Internet Res 2017 Dec 18;19(12):e422. doi: 10.2196/jmir.9255. PMID: 29254906Free PMC Article

Recent clinical studies

Etiology

Development and External Validation of a Mortality Prediction Model for Community-Dwelling Older Adults With Dementia.
Deardorff WJ, Barnes DE, Jeon SY, Boscardin WJ, Langa KM, Covinsky KE, Mitchell SL, Whitlock EL, Smith AK, Lee SJ
JAMA Intern Med 2022 Nov 1;182(11):1161-1170. doi: 10.1001/jamainternmed.2022.4326. PMID: 36156062Free PMC Article
Pharmacotherapy for Spine-Related Pain in Older Adults.
Fu JL, Perloff MD
Drugs Aging 2022 Jul;39(7):523-550. Epub 2022 Jun 27 doi: 10.1007/s40266-022-00946-x. PMID: 35754070
Stroke.
Mansfield A, Inness EL, Mcilroy WE
Handb Clin Neurol 2018;159:205-228. doi: 10.1016/B978-0-444-63916-5.00013-6. PMID: 30482315
Locomotive syndrome: clinical perspectives.
Ikemoto T, Arai YC
Clin Interv Aging 2018;13:819-827. Epub 2018 Apr 30 doi: 10.2147/CIA.S148683. PMID: 29750024Free PMC Article
Septic sacroiliitis.
Osman AA, Govender S
Clin Orthop Relat Res 1995 Apr;(313):214-9. PMID: 7641483

Diagnosis

Pharmacotherapy for Spine-Related Pain in Older Adults.
Fu JL, Perloff MD
Drugs Aging 2022 Jul;39(7):523-550. Epub 2022 Jun 27 doi: 10.1007/s40266-022-00946-x. PMID: 35754070
Phosphaturic Mesenchymal Tumor.
Benson JC, Trejo-Lopez JA, Nassiri AM, Eschbacher K, Link MJ, Driscoll CL, Tiegs RD, Sfeir J, DeLone DR
AJNR Am J Neuroradiol 2022 Jun;43(6):817-822. Epub 2022 May 19 doi: 10.3174/ajnr.A7513. PMID: 35589138Free PMC Article
Locomotive syndrome: clinical perspectives.
Ikemoto T, Arai YC
Clin Interv Aging 2018;13:819-827. Epub 2018 Apr 30 doi: 10.2147/CIA.S148683. PMID: 29750024Free PMC Article
Osteomalacia as a result of vitamin D deficiency.
Bhan A, Rao AD, Rao DS
Endocrinol Metab Clin North Am 2010 Jun;39(2):321-31, table of contents. doi: 10.1016/j.ecl.2010.02.001. PMID: 20511054
Septic sacroiliitis.
Osman AA, Govender S
Clin Orthop Relat Res 1995 Apr;(313):214-9. PMID: 7641483

Therapy

Current status and challenges of percutaneous vertebroplasty (PVP).
Noguchi T, Yamashita K, Kamei R, Maehara J
Jpn J Radiol 2023 Jan;41(1):1-13. Epub 2022 Aug 9 doi: 10.1007/s11604-022-01322-w. PMID: 35943687Free PMC Article
Tantali fibromyalgic supplicium: Is there any relief with the antidepressant employment? A systematic review.
Ilari S, Passacatini LC, Malafoglia V, Oppedisano F, Maiuolo J, Gliozzi M, Palma E, Tomino C, Fini M, Raffaeli W, Mollace V, Muscoli C
Pharmacol Res 2022 Dec;186:106547. Epub 2022 Nov 4 doi: 10.1016/j.phrs.2022.106547. PMID: 36336218
Pharmacotherapy for Spine-Related Pain in Older Adults.
Fu JL, Perloff MD
Drugs Aging 2022 Jul;39(7):523-550. Epub 2022 Jun 27 doi: 10.1007/s40266-022-00946-x. PMID: 35754070
Mental practice for treating upper extremity deficits in individuals with hemiparesis after stroke.
Barclay RE, Stevenson TJ, Poluha W, Semenko B, Schubert J
Cochrane Database Syst Rev 2020 May 25;5(5):CD005950. doi: 10.1002/14651858.CD005950.pub5. PMID: 32449959Free PMC Article
Osteomalacia as a result of vitamin D deficiency.
Bhan A, Rao AD, Rao DS
Endocrinol Metab Clin North Am 2010 Jun;39(2):321-31, table of contents. doi: 10.1016/j.ecl.2010.02.001. PMID: 20511054

Prognosis

Development and External Validation of a Mortality Prediction Model for Community-Dwelling Older Adults With Dementia.
Deardorff WJ, Barnes DE, Jeon SY, Boscardin WJ, Langa KM, Covinsky KE, Mitchell SL, Whitlock EL, Smith AK, Lee SJ
JAMA Intern Med 2022 Nov 1;182(11):1161-1170. doi: 10.1001/jamainternmed.2022.4326. PMID: 36156062Free PMC Article
Pharmacotherapy for Spine-Related Pain in Older Adults.
Fu JL, Perloff MD
Drugs Aging 2022 Jul;39(7):523-550. Epub 2022 Jun 27 doi: 10.1007/s40266-022-00946-x. PMID: 35754070
Osteomalacia as a result of vitamin D deficiency.
Bhan A, Rao AD, Rao DS
Endocrinol Metab Clin North Am 2010 Jun;39(2):321-31, table of contents. doi: 10.1016/j.ecl.2010.02.001. PMID: 20511054
Septic sacroiliitis.
Osman AA, Govender S
Clin Orthop Relat Res 1995 Apr;(313):214-9. PMID: 7641483
Normal pressure hydrocephalus in geriatric medicine: a challenge.
St-Laurent M
J Geriatr Psychiatry Neurol 1988 Jul-Sep;1(3):163-8. doi: 10.1177/089198878800100306. PMID: 3075497

Clinical prediction guides

Current status and challenges of percutaneous vertebroplasty (PVP).
Noguchi T, Yamashita K, Kamei R, Maehara J
Jpn J Radiol 2023 Jan;41(1):1-13. Epub 2022 Aug 9 doi: 10.1007/s11604-022-01322-w. PMID: 35943687Free PMC Article
Development and External Validation of a Mortality Prediction Model for Community-Dwelling Older Adults With Dementia.
Deardorff WJ, Barnes DE, Jeon SY, Boscardin WJ, Langa KM, Covinsky KE, Mitchell SL, Whitlock EL, Smith AK, Lee SJ
JAMA Intern Med 2022 Nov 1;182(11):1161-1170. doi: 10.1001/jamainternmed.2022.4326. PMID: 36156062Free PMC Article
Mental practice for treating upper extremity deficits in individuals with hemiparesis after stroke.
Barclay RE, Stevenson TJ, Poluha W, Semenko B, Schubert J
Cochrane Database Syst Rev 2020 May 25;5(5):CD005950. doi: 10.1002/14651858.CD005950.pub5. PMID: 32449959Free PMC Article
Osteoarthritis-related difficulty walking and risk for diabetes complications.
Hawker GA, Croxford R, Bierman AS, Harvey P, Ravi B, Kendzerska T, Stanaitis I, King LK, Lipscombe L
Osteoarthritis Cartilage 2017 Jan;25(1):67-75. Epub 2016 Aug 16 doi: 10.1016/j.joca.2016.08.003. PMID: 27539890
Normal pressure hydrocephalus in geriatric medicine: a challenge.
St-Laurent M
J Geriatr Psychiatry Neurol 1988 Jul-Sep;1(3):163-8. doi: 10.1177/089198878800100306. PMID: 3075497

Recent systematic reviews

Covid-19 vaccines and neurological complications: a systematic review.
Allahyari F, Molaee H, Hosseini Nejad J
Z Naturforsch C J Biosci 2023 Jan 27;78(1-2):1-8. Epub 2022 Sep 12 doi: 10.1515/znc-2022-0092. PMID: 36087300
Tantali fibromyalgic supplicium: Is there any relief with the antidepressant employment? A systematic review.
Ilari S, Passacatini LC, Malafoglia V, Oppedisano F, Maiuolo J, Gliozzi M, Palma E, Tomino C, Fini M, Raffaeli W, Mollace V, Muscoli C
Pharmacol Res 2022 Dec;186:106547. Epub 2022 Nov 4 doi: 10.1016/j.phrs.2022.106547. PMID: 36336218
Mental practice for treating upper extremity deficits in individuals with hemiparesis after stroke.
Barclay RE, Stevenson TJ, Poluha W, Semenko B, Schubert J
Cochrane Database Syst Rev 2020 May 25;5(5):CD005950. doi: 10.1002/14651858.CD005950.pub5. PMID: 32449959Free PMC Article
Content validity of symptom-based measures for diabetic, chemotherapy, and HIV peripheral neuropathy.
Gewandter JS, Burke L, Cavaletti G, Dworkin RH, Gibbons C, Gover TD, Herrmann DN, Mcarthur JC, McDermott MP, Rappaport BA, Reeve BB, Russell JW, Smith AG, Smith SM, Turk DC, Vinik AI, Freeman R
Muscle Nerve 2017 Mar;55(3):366-372. Epub 2016 Dec 23 doi: 10.1002/mus.25264. PMID: 27447116Free PMC Article
Poststroke knowledge and symptom awareness: a global issue for secondary stroke prevention.
Ellis C, Barley J, Grubaugh A
Cerebrovasc Dis 2013;35(6):572-81. Epub 2013 Jul 6 doi: 10.1159/000351209. PMID: 23838851

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    Related information

    • ClinVar
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      Related information in GTR
    • GTR(Clinical)
      Clinical tests in GTR
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