From HPO
Azoospermia- MedGen UID:
- 2150
- •Concept ID:
- C0004509
- •
- Disease or Syndrome
Absence of any measurable level of sperm,whereby spermatozoa cannot be observed even after centrifugation of the semen pellet.
Cryptorchidism- MedGen UID:
- 8192
- •Concept ID:
- C0010417
- •
- Congenital Abnormality
Cryptorchidism, or failure of testicular descent, is a common human congenital abnormality with a multifactorial etiology that likely reflects the involvement of endocrine, environmental, and hereditary factors. Cryptorchidism can result in infertility and increases risk for testicular tumors. Testicular descent from abdomen to scrotum occurs in 2 distinct phases: the transabdominal phase and the inguinoscrotal phase (summary by Gorlov et al., 2002).
Infertility disorder- MedGen UID:
- 43876
- •Concept ID:
- C0021359
- •
- Finding
Inability to conceive for at least one year after trying and having unprotected sex. Causes of female infertility include endometriosis, fallopian tubes obstruction, and polycystic ovary syndrome. Causes of male infertility include abnormal sperm production or function, blockage of the epididymis, blockage of the ejaculatory ducts, hypospadias, exposure to pesticides, and health related issues.
Male pseudohermaphroditism- MedGen UID:
- 68666
- •Concept ID:
- C0238395
- •
- Congenital Abnormality
Hermaphroditism refers to a discrepancy between the morphology of the gonads and that of the external genitalia. In male pseudohermaphroditism, the genotype is male (XY) and the external genitalia are imcompletely virilized, ambiguous, or complete female. If gonads are present, they are testes.
Absent vas deferens- MedGen UID:
- 539922
- •Concept ID:
- C0266444
- •
- Congenital Abnormality
Aplasia (congenital absence) of the vas deferens.
Bifid scrotum- MedGen UID:
- 90968
- •Concept ID:
- C0341787
- •
- Congenital Abnormality
Midline indentation or cleft of the scrotum.
Perineal hypospadias- MedGen UID:
- 105292
- •Concept ID:
- C0452148
- •
- Congenital Abnormality
Hypospadias with location of the urethral meatus in the perineal region.
Micropenis- MedGen UID:
- 1633603
- •Concept ID:
- C4551492
- •
- Congenital Abnormality
Abnormally small penis. At birth, the normal penis is about 3 cm (stretched length from pubic tubercle to tip of penis) with micropenis less than 2.0-2.5 cm.
Abnormal rib cage morphology- MedGen UID:
- 871275
- •Concept ID:
- C4025763
- •
- Anatomical Abnormality
A morphological anomaly of the rib cage.
Hypogonadism- MedGen UID:
- 5711
- •Concept ID:
- C0020619
- •
- Disease or Syndrome
A decreased functionality of the gonad.
Gynecomastia- MedGen UID:
- 6694
- •Concept ID:
- C0018418
- •
- Disease or Syndrome
Abnormal development of large mammary glands in males resulting in breast enlargement.
- Abnormality of the breast
- Abnormality of the endocrine system
- Abnormality of the genitourinary system
- Abnormality of the musculoskeletal system