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Cyst of parathyroid

MedGen UID:
90980
•Concept ID:
C0342347
•
Anatomical Abnormality
Synonyms: Cyst of Parathyroid; Cyst of the Parathyroid; Parathyroid cyst; Parathyroid Cyst
SNOMED CT: Cyst of parathyroid (190459003); Parathyroid cyst (190459003)

Definition

An epithelium-lined, fluid-filled cyst containing parathyroid hormone that is usually located in an inferior parathyroid gland, but may be found in other locations in the neck or mediastinum. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCyst of parathyroid

Professional guidelines

PubMed

Treatment of Hypercalcemia of Malignancy in Adults: An Endocrine Society Clinical Practice Guideline.
El-Hajj Fuleihan G, Clines GA, Hu MI, Marcocci C, Murad MH, Piggott T, Van Poznak C, Wu JY, Drake MT
J Clin Endocrinol Metab 2023 Feb 15;108(3):507-528. doi: 10.1210/clinem/dgac621. PMID: 36545746
2021 American Thyroid Association Guidelines for Management of Patients with Anaplastic Thyroid Cancer.
Bible KC, Kebebew E, Brierley J, Brito JP, Cabanillas ME, Clark TJ Jr, Di Cristofano A, Foote R, Giordano T, Kasperbauer J, Newbold K, Nikiforov YE, Randolph G, Rosenthal MS, Sawka AM, Shah M, Shaha A, Smallridge R, Wong-Clark CK
Thyroid 2021 Mar;31(3):337-386. doi: 10.1089/thy.2020.0944. PMID: 33728999Free PMC Article
The diagnosis and management of hypercalcaemia.
Minisola S, Pepe J, Piemonte S, Cipriani C
BMJ 2015 Jun 2;350:h2723. doi: 10.1136/bmj.h2723. PMID: 26037642

Recent clinical studies

Etiology

Surgical treatment of thyroid cancer: Established and novel approaches.
Pace-Asciak P, Russell JO, Tufano RP
Best Pract Res Clin Endocrinol Metab 2023 Jan;37(1):101664. Epub 2022 Apr 29 doi: 10.1016/j.beem.2022.101664. PMID: 35534363
Surgery for primary hyperparathyroidism.
das Neves MC, Santos RO, Ohe MN
Arch Endocrinol Metab 2022 Nov 11;66(5):678-688. doi: 10.20945/2359-3997000000557. PMID: 36382757Free PMC Article
Analytical performance of the ThyroSeq v3 genomic classifier for cancer diagnosis in thyroid nodules.
Nikiforova MN, Mercurio S, Wald AI, Barbi de Moura M, Callenberg K, Santana-Santos L, Gooding WE, Yip L, Ferris RL, Nikiforov YE
Cancer 2018 Apr 15;124(8):1682-1690. Epub 2018 Jan 18 doi: 10.1002/cncr.31245. PMID: 29345728Free PMC Article
The use of near-infrared fluorescence imaging in endocrine surgical procedures.
Kahramangil B, Berber E
J Surg Oncol 2017 Jun;115(7):848-855. Epub 2017 Feb 15 doi: 10.1002/jso.24583. PMID: 28205245
Primary hyperparathyroidism.
Akerström G, Hellman P
Curr Opin Oncol 2004 Jan;16(1):1-7. doi: 10.1097/00001622-200401000-00002. PMID: 14685084

Diagnosis

Parathyroid Imaging.
Lalonde MN, Correia RD, Syktiotis GP, Schaefer N, Matter M, Prior JO
Semin Nucl Med 2023 Jul;53(4):490-502. Epub 2023 Mar 14 doi: 10.1053/j.semnuclmed.2023.02.004. PMID: 36922339
Overview of the 2022 WHO Classification of Parathyroid Tumors.
Erickson LA, Mete O, Juhlin CC, Perren A, Gill AJ
Endocr Pathol 2022 Mar;33(1):64-89. Epub 2022 Feb 17 doi: 10.1007/s12022-022-09709-1. PMID: 35175514
Parathyroid Pathology.
Guilmette J, Sadow PM
Surg Pathol Clin 2019 Dec;12(4):1007-1019. Epub 2019 Sep 27 doi: 10.1016/j.path.2019.08.006. PMID: 31672291Free PMC Article
Parathyromatosis and parathyroid cancer.
Shen WT
Cancer Treat Res 2010;153:105-16. doi: 10.1007/978-1-4419-0857-5_7. PMID: 19957222
Parathyroid tumors.
Granberg PO, Cedermark B, Farnebo LO, Hamberger B, Werner S
Curr Probl Cancer 1985 Nov;9(11):1-52. doi: 10.1016/s0147-0272(85)80035-0. PMID: 3905268

Therapy

Lithium-associated hyperparathyroidism.
Mifsud S, Cilia K, Mifsud EL, Gruppetta M
Br J Hosp Med (Lond) 2020 Nov 2;81(11):1-9. Epub 2020 Nov 17 doi: 10.12968/hmed.2020.0457. PMID: 33263481
Parathyroid tumors.
Granberg PO, Cedermark B, Farnebo LO, Hamberger B, Werner S
Curr Probl Cancer 1985 Nov;9(11):1-52. doi: 10.1016/s0147-0272(85)80035-0. PMID: 3905268
Primary immunodeficiency.
Rosen FS
Pediatr Clin North Am 1974 Aug;21(3):533-49. doi: 10.1016/s0031-3955(16)33023-1. PMID: 4137895
Clinical applications of radioimmunoassay of plasma parathyroid hormone.
Berson SA, Yalow RS
Am J Med 1971 May;50(5):623-9. doi: 10.1016/0002-9343(71)90117-3. PMID: 4930270
The clinical physiology of calcium homeostasis, parathyroid hormone, and calcitonin. II.
Kleeman CR, Massry SG, Coburn JW
Calif Med 1971 Apr;114(4):19-30. PMID: 4927915Free PMC Article

Prognosis

Parathyroid Imaging.
Itani M, Middleton WD
Radiol Clin North Am 2020 Nov;58(6):1071-1083. Epub 2020 Sep 17 doi: 10.1016/j.rcl.2020.07.006. PMID: 33040849
Non-Neoplastic Mediastinal Cysts.
Syred K, Weissferdt A
Adv Anat Pathol 2020 Sep;27(5):294-302. doi: 10.1097/PAP.0000000000000261. PMID: 31972565
Analytical performance of the ThyroSeq v3 genomic classifier for cancer diagnosis in thyroid nodules.
Nikiforova MN, Mercurio S, Wald AI, Barbi de Moura M, Callenberg K, Santana-Santos L, Gooding WE, Yip L, Ferris RL, Nikiforov YE
Cancer 2018 Apr 15;124(8):1682-1690. Epub 2018 Jan 18 doi: 10.1002/cncr.31245. PMID: 29345728Free PMC Article
Parathyromatosis and parathyroid cancer.
Shen WT
Cancer Treat Res 2010;153:105-16. doi: 10.1007/978-1-4419-0857-5_7. PMID: 19957222
Parathyroid tumors.
Granberg PO, Cedermark B, Farnebo LO, Hamberger B, Werner S
Curr Probl Cancer 1985 Nov;9(11):1-52. doi: 10.1016/s0147-0272(85)80035-0. PMID: 3905268

Clinical prediction guides

Use of Vascular Clues to Locate Ectopic Parathyroid Glands and Predict Anatomic Abnormalities.
Battista RA, Noel JE, Orloff LA
JAMA Otolaryngol Head Neck Surg 2021 Feb 1;147(2):211-213. doi: 10.1001/jamaoto.2020.3749. PMID: 33090209
The use of near-infrared fluorescence imaging in endocrine surgical procedures.
Kahramangil B, Berber E
J Surg Oncol 2017 Jun;115(7):848-855. Epub 2017 Feb 15 doi: 10.1002/jso.24583. PMID: 28205245
Magnesium: its role in nutrition and carcinogenesis.
Blaszczyk U, Duda-Chodak A
Rocz Panstw Zakl Hig 2013;64(3):165-71. PMID: 24325082
Sestamibi parathyroid imaging.
McBiles M, Lambert AT, Cote MG, Kim SY
Semin Nucl Med 1995 Jul;25(3):221-34. doi: 10.1016/s0001-2998(95)80012-3. PMID: 7570042
Parathyroid cytopathology.
Davey DD, Glant MD, Berger EK
Diagn Cytopathol 1986 Jan-Mar;2(1):76-80. doi: 10.1002/dc.2840020116. PMID: 2424691

Recent systematic reviews

Treatment of hypercalcaemia of malignancy in adults.
Mc Donald D, Drake MT, Crowley RK
Clin Med (Lond) 2023 Sep;23(5):503-507. Epub 2023 Sep 29 doi: 10.7861/clinmed.2023-0227. PMID: 37775175Free PMC Article
Diagnosis and management of parathyroid carcinoma: a state-of-the-art review.
Roser P, Leca BM, Coelho C, Schulte KM, Gilbert J, Drakou EE, Kosmas C, Ling Chuah L, Wassati H, Miras AD, Crane J, Aylwin SJB, Grossman AB, Dimitriadis GK
Endocr Relat Cancer 2023 Apr 1;30(4) Epub 2023 Mar 22 doi: 10.1530/ERC-22-0287. PMID: 36621911
Treatment of Hypercalcemia of Malignancy in Adults: An Endocrine Society Clinical Practice Guideline.
El-Hajj Fuleihan G, Clines GA, Hu MI, Marcocci C, Murad MH, Piggott T, Van Poznak C, Wu JY, Drake MT
J Clin Endocrinol Metab 2023 Feb 15;108(3):507-528. doi: 10.1210/clinem/dgac621. PMID: 36545746
Parathyroid Cystic Adenoma: A Systematic Review and Meta-Analysis.
Daoud A, Ronen O
Endocr Pract 2023 Jan;29(1):2-10. Epub 2022 Nov 10 doi: 10.1016/j.eprac.2022.11.004. PMID: 36370985
2021 American Thyroid Association Guidelines for Management of Patients with Anaplastic Thyroid Cancer.
Bible KC, Kebebew E, Brierley J, Brito JP, Cabanillas ME, Clark TJ Jr, Di Cristofano A, Foote R, Giordano T, Kasperbauer J, Newbold K, Nikiforov YE, Randolph G, Rosenthal MS, Sawka AM, Shah M, Shaha A, Smallridge R, Wong-Clark CK
Thyroid 2021 Mar;31(3):337-386. doi: 10.1089/thy.2020.0944. PMID: 33728999Free PMC Article

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