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Recurrent Acute Myeloid Leukemia, Myelodysplasia-Related

MedGen UID:
902081
Concept ID:
C4086782
Neoplastic Process
Synonyms: Recurrent Acute Myeloid Leukemia with Myelodysplasia-Related Changes; Recurrent HRMDS; Recurrent Myelodysplastic Syndrome; Relapsed or Refractory High-Risk Myelodysplastic Syndrome; Relapsed or Refractory HRMDS

Definition

The reemergence of acute myeloid leukemia, myelodysplasia-related after a period of remission. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRecurrent Acute Myeloid Leukemia, Myelodysplasia-Related

Professional guidelines

PubMed

Park HS, Kim HK, Kim HS, Yang Y, Han HS, Lee KH, Son BR, Kwon J
Ann Hematol 2022 Dec;101(12):2645-2654. Epub 2022 Oct 12 doi: 10.1007/s00277-022-05002-7. PMID: 36220882
Margolskee E, Mikita G, Rea B, Bagg A, Zuo Z, Sun Y, Goswami M, Wang SA, Oak J, Arber DA, Allen MB, George TI, Rogers HJ, Hsi E, Hasserjian RP, Orazi A
Mod Pathol 2018 Jun;31(6):873-880. Epub 2018 Feb 5 doi: 10.1038/s41379-018-0001-2. PMID: 29403082
Davis KL, Marina N, Arber DA, Ma L, Cherry A, Dahl GV, Heerema-McKenney A
Am J Clin Pathol 2013 Jun;139(6):818-25. doi: 10.1309/AJCP59WKRZVNHETN. PMID: 23690127

Recent clinical studies

Etiology

Gurney M, Chekkaf I, Baranwal A, Basmaci R, Katamesh B, Greipp P, Foran JM, Badar T, Mangaonkar AA, Begna KH, Gangat N, Patnaik MM, Litzow MR, Shah MV, Viswanatha DS, He R, Alkhateeb HB, Al-Kali A
Br J Haematol 2023 Jul;202(2):279-283. Epub 2023 May 5 doi: 10.1111/bjh.18850. PMID: 37144345
Weinberg OK, Porwit A, Orazi A, Hasserjian RP, Foucar K, Duncavage EJ, Arber DA
Virchows Arch 2023 Jan;482(1):27-37. Epub 2022 Oct 20 doi: 10.1007/s00428-022-03430-4. PMID: 36264379
Richard-Carpentier G, DiNardo CD
Hematology Am Soc Hematol Educ Program 2019 Dec 6;2019(1):548-556. doi: 10.1182/hematology.2019000059. PMID: 31808888Free PMC Article
Ikegawa S, Doki N, Kurosawa S, Yamaguchi T, Sakaguchi M, Harada K, Yamamoto K, Hino Y, Shingai N, Senoo Y, Watanabe K, Igarashi A, Najima Y, Kobayashi T, Kakihana K, Sakamaki H, Ohashi K
Leuk Lymphoma 2016;57(1):76-80. doi: 10.3109/10428194.2015.1063148. PMID: 26084204
Lin P, Falini B
Am J Clin Pathol 2015 Jul;144(1):19-28. doi: 10.1309/AJCP97BJBEVZEUIN. PMID: 26071459

Diagnosis

Weinberg OK, Porwit A, Orazi A, Hasserjian RP, Foucar K, Duncavage EJ, Arber DA
Virchows Arch 2023 Jan;482(1):27-37. Epub 2022 Oct 20 doi: 10.1007/s00428-022-03430-4. PMID: 36264379
Richard-Carpentier G, DiNardo CD
Hematology Am Soc Hematol Educ Program 2019 Dec 6;2019(1):548-556. doi: 10.1182/hematology.2019000059. PMID: 31808888Free PMC Article
Jung J, Cho BS, Kim HJ, Han E, Jang W, Han K, Lee JW, Chung NG, Cho B, Kim M, Kim Y
Ann Lab Med 2019 May;39(3):311-316. doi: 10.3343/alm.2019.39.3.311. PMID: 30623623Free PMC Article
Duffield AS, Aoki J, Levis M, Cowan K, Gocke CD, Burns KH, Borowitz MJ, Vuica-Ross M
Am J Clin Pathol 2012 Mar;137(3):395-402. doi: 10.1309/AJCPE0MV0YTWLUUE. PMID: 22338051Free PMC Article
Yin CC, Medeiros LJ, Bueso-Ramos CE
Int J Lab Hematol 2010 Oct;32(5):461-76. Epub 2010 Jul 7 doi: 10.1111/j.1751-553X.2010.01246.x. PMID: 20626469Free PMC Article

Therapy

Leroy H, Gadaud N, Bérard E, Klein E, Luquet I, Vial JP, Rieu JB, Lechevalier N, Tavitian S, Leguay T, Largeaud L, Bidet A, Delabesse E, Sarry A, de Grande AC, Récher C, Pigneux A, Bertoli S, Dumas PY
Cancer Med 2024 Feb;13(3):e7003. doi: 10.1002/cam4.7003. PMID: 38400682Free PMC Article
Thol F
Hematology Am Soc Hematol Educ Program 2021 Dec 10;2021(1):16-23. doi: 10.1182/hematology.2021000309. PMID: 34889359Free PMC Article
Richard-Carpentier G, DiNardo CD
Hematology Am Soc Hematol Educ Program 2019 Dec 6;2019(1):548-556. doi: 10.1182/hematology.2019000059. PMID: 31808888Free PMC Article
Ikegawa S, Doki N, Kurosawa S, Yamaguchi T, Sakaguchi M, Harada K, Yamamoto K, Hino Y, Shingai N, Senoo Y, Watanabe K, Igarashi A, Najima Y, Kobayashi T, Kakihana K, Sakamaki H, Ohashi K
Leuk Lymphoma 2016;57(1):76-80. doi: 10.3109/10428194.2015.1063148. PMID: 26084204
Cui W, Zhang D, Cunningham MT, Tilzer L
Int J Lab Hematol 2014 Dec;36(6):636-49. Epub 2014 Mar 6 doi: 10.1111/ijlh.12193. PMID: 24602197

Prognosis

Gurney M, Chekkaf I, Baranwal A, Basmaci R, Katamesh B, Greipp P, Foran JM, Badar T, Mangaonkar AA, Begna KH, Gangat N, Patnaik MM, Litzow MR, Shah MV, Viswanatha DS, He R, Alkhateeb HB, Al-Kali A
Br J Haematol 2023 Jul;202(2):279-283. Epub 2023 May 5 doi: 10.1111/bjh.18850. PMID: 37144345
Richard-Carpentier G, DiNardo CD
Hematology Am Soc Hematol Educ Program 2019 Dec 6;2019(1):548-556. doi: 10.1182/hematology.2019000059. PMID: 31808888Free PMC Article
Ikegawa S, Doki N, Kurosawa S, Yamaguchi T, Sakaguchi M, Harada K, Yamamoto K, Hino Y, Shingai N, Senoo Y, Watanabe K, Igarashi A, Najima Y, Kobayashi T, Kakihana K, Sakamaki H, Ohashi K
Leuk Lymphoma 2016;57(1):76-80. doi: 10.3109/10428194.2015.1063148. PMID: 26084204
Lin P, Falini B
Am J Clin Pathol 2015 Jul;144(1):19-28. doi: 10.1309/AJCP97BJBEVZEUIN. PMID: 26071459
Duffield AS, Aoki J, Levis M, Cowan K, Gocke CD, Burns KH, Borowitz MJ, Vuica-Ross M
Am J Clin Pathol 2012 Mar;137(3):395-402. doi: 10.1309/AJCPE0MV0YTWLUUE. PMID: 22338051Free PMC Article

Clinical prediction guides

Stiff A, Fornerod M, Kain BN, Nicolet D, Kelly BJ, Miller KE, Mrózek K, Boateng I, Bollas A, Garfinkle EAR, Momoh O, Fasola FA, Olawumi HO, Mencia-Trinchant N, Kloppers JF, van Marle AC, Hu E, Wijeratne S, Wheeler G, Walker CJ, Buss J, Heyrosa A, Desai H, Laganson A, Hamp E, Abu-Shihab Y, Abaza H, Kronen P, Sen S, Johnstone ME, Quinn K, Wronowski B, Hertlein E, Miles LA, Mims AS, Oakes CC, Blachly JS, Larkin KT, Mundy-Bosse B, Carroll AJ, Powell BL, Kolitz JE, Stone RM, Duarte C, Abbott D, Amaya ML, Jordan CT, Uy GL, Stock W, Archer KJ, Paskett ED, Guzman ML, Levine RL, Menghrajani K, Chakravarty D, Berger MF, Bottomly D, McWeeney SK, Tyner JW, Byrd JC, Salomonis N, Grimes HL, Mardis ER, Eisfeld AK
Nat Genet 2024 Nov;56(11):2434-2446. Epub 2024 Oct 4 doi: 10.1038/s41588-024-01929-x. PMID: 39367245Free PMC Article
Hu RH, Su L, Lan XX, Chang XL, Hui WH, Guo YX, Zhao H, Zhang Y, Sun WL
Anticancer Drugs 2023 Mar 1;34(3):344-350. Epub 2022 Nov 17 doi: 10.1097/CAD.0000000000001431. PMID: 36622759Free PMC Article
Park HS, Kim HK, Kim HS, Yang Y, Han HS, Lee KH, Son BR, Kwon J
Ann Hematol 2022 Dec;101(12):2645-2654. Epub 2022 Oct 12 doi: 10.1007/s00277-022-05002-7. PMID: 36220882
Margolskee E, Mikita G, Rea B, Bagg A, Zuo Z, Sun Y, Goswami M, Wang SA, Oak J, Arber DA, Allen MB, George TI, Rogers HJ, Hsi E, Hasserjian RP, Orazi A
Mod Pathol 2018 Jun;31(6):873-880. Epub 2018 Feb 5 doi: 10.1038/s41379-018-0001-2. PMID: 29403082
Cui W, Zhang D, Cunningham MT, Tilzer L
Int J Lab Hematol 2014 Dec;36(6):636-49. Epub 2014 Mar 6 doi: 10.1111/ijlh.12193. PMID: 24602197

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