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Abnormal circulating insulin concentration

MedGen UID:: 893016
•Concept ID:: C4073160
•: Finding

Synonym:	Abnormal insulin level

HPO:	HP:0040214

Definition

An abnormal concentration of insulin in the body. [from HPO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVAbnormal circulating insulin concentration

Professional guidelines

PubMed

Circulating Levels of Nesfatin-1 and Spexin in Children with Prader-Willi Syndrome during Growth Hormone Treatment and Dietary Intervention.

Gajewska J, Szamotulska K, Klemarczyk W, Chełchowska M, Strucińska M, Ambroszkiewicz J
Nutrients 2023 Mar 1;15(5) doi: 10.3390/nu15051240. PMID: 36904239 Free PMC Article

Quantitative measurement of IGF-I and its use in diagnosing and monitoring treatment of disorders of growth hormone secretion.

Clemmons DR
Endocr Dev 2005;9:55-65. doi: 10.1159/000085756. PMID: 15879688

Clinical utility of sex hormone-binding globulin measurement.

Pugeat M, Crave JC, Tourniaire J, Forest MG
Horm Res 1996;45(3-5):148-55. doi: 10.1159/000184778. PMID: 8964574

See all (9)

Recent clinical studies

Etiology

PCOS during the menopausal transition and after menopause: a systematic review and meta-analysis.

Millán-de-Meer M, Luque-Ramírez M, Nattero-Chávez L, Escobar-Morreale HF
Hum Reprod Update 2023 Nov 2;29(6):741-772. doi: 10.1093/humupd/dmad015. PMID: 37353908

Associations of cord blood meta-inflammation and vitamin D with neurodevelopmental delay: A prospective birth cohort study in China.

Wang P, Wu L, Yin WJ, Tao RX, Zhang Y, Li PP, Jiang XM, Shao ZY, Zhu P
Front Immunol 2022;13:1078340. Epub 2023 Jan 4 doi: 10.3389/fimmu.2022.1078340. PMID: 36685522 Free PMC Article

Stress Cardiac Biomarkers, Cardiovascular and Renal Outcomes, and Response to Canagliflozin.

Vaduganathan M, Sattar N, Xu J, Butler J, Mahaffey KW, Neal B, Shaw W, Rosenthal N, Pfeifer M, Hansen MK, Januzzi JL Jr
J Am Coll Cardiol 2022 Feb 8;79(5):432-444. doi: 10.1016/j.jacc.2021.11.027. PMID: 35115099 Free PMC Article

Circulating Bile Acid Profiles: A Need for Further Examination.

Qi L, Tian Y, Chen Y
J Clin Endocrinol Metab 2021 Oct 21;106(11):3093-3112. doi: 10.1210/clinem/dgab531. PMID: 34279029

Cholecystectomy and risk of metabolic syndrome.

Di Ciaula A, Garruti G, Wang DQ, Portincasa P
Eur J Intern Med 2018 Jul;53:3-11. Epub 2018 Apr 26 doi: 10.1016/j.ejim.2018.04.019. PMID: 29706426 Free PMC Article

See all (235)

Diagnosis

PCOS during the menopausal transition and after menopause: a systematic review and meta-analysis.

Millán-de-Meer M, Luque-Ramírez M, Nattero-Chávez L, Escobar-Morreale HF
Hum Reprod Update 2023 Nov 2;29(6):741-772. doi: 10.1093/humupd/dmad015. PMID: 37353908

Stress Cardiac Biomarkers, Cardiovascular and Renal Outcomes, and Response to Canagliflozin.

Exercise and Regulation of Carbohydrate Metabolism.

Mul JD, Stanford KI, Hirshman MF, Goodyear LJ
Prog Mol Biol Transl Sci 2015;135:17-37. Epub 2015 Aug 20 doi: 10.1016/bs.pmbts.2015.07.020. PMID: 26477909 Free PMC Article

Contribution of triglyceride-rich lipoproteins to plasma free fatty acids.

Miles JM, Nelson RH
Horm Metab Res 2007 Oct;39(10):726-9. doi: 10.1055/s-2007-990273. PMID: 17952834

Control of glycaemia.

Gerich JE
Baillieres Clin Endocrinol Metab 1993 Jul;7(3):551-86. doi: 10.1016/s0950-351x(05)80207-1. PMID: 8379904

See all (141)

Therapy

PCOS during the menopausal transition and after menopause: a systematic review and meta-analysis.

Millán-de-Meer M, Luque-Ramírez M, Nattero-Chávez L, Escobar-Morreale HF
Hum Reprod Update 2023 Nov 2;29(6):741-772. doi: 10.1093/humupd/dmad015. PMID: 37353908

Stress Cardiac Biomarkers, Cardiovascular and Renal Outcomes, and Response to Canagliflozin.

Reduced microvascular hyperaemia in subjects at risk of developing type 2 (non-insulin-dependent) diabetes mellitus.

Jaap AJ, Hammersley MS, Shore AC, Tooke JE
Diabetologia 1994 Feb;37(2):214-6. doi: 10.1007/s001250050096. PMID: 8163058

Dichloroacetate.

Stacpoole PW, Greene YJ
Diabetes Care 1992 Jun;15(6):785-91. doi: 10.2337/diacare.15.6.785. PMID: 1600837

Diabetes and exercise.

Zinman B, Vranic M
Med Clin North Am 1985 Jan;69(1):145-57. doi: 10.1016/s0025-7125(16)31062-8. PMID: 3883072

See all (113)

Prognosis

PCOS during the menopausal transition and after menopause: a systematic review and meta-analysis.

Millán-de-Meer M, Luque-Ramírez M, Nattero-Chávez L, Escobar-Morreale HF
Hum Reprod Update 2023 Nov 2;29(6):741-772. doi: 10.1093/humupd/dmad015. PMID: 37353908

Stress Cardiac Biomarkers, Cardiovascular and Renal Outcomes, and Response to Canagliflozin.

Circulating Bile Acid Profiles: A Need for Further Examination.

Qi L, Tian Y, Chen Y
J Clin Endocrinol Metab 2021 Oct 21;106(11):3093-3112. doi: 10.1210/clinem/dgab531. PMID: 34279029

Oxidative stress and cardiovascular complications in polycystic ovarian syndrome.

Hyderali BN, Mala K
Eur J Obstet Gynecol Reprod Biol 2015 Aug;191:15-22. Epub 2015 Jun 2 doi: 10.1016/j.ejogrb.2015.05.005. PMID: 26066290

Importance of pH homeostasis in metabolic health and diseases: crucial role of membrane proton transport.

Aoi W, Marunaka Y
Biomed Res Int 2014;2014:598986. Epub 2014 Sep 11 doi: 10.1155/2014/598986. PMID: 25302301 Free PMC Article

See all (65)

Clinical prediction guides

SERCA2 regulates proinsulin processing and processing enzyme maturation in pancreatic beta cells.

Iida H, Kono T, Lee CC, Krishnan P, Arvin MC, Weaver SA, Jarvela TS, Branco RCS, McLaughlin MR, Bone RN, Tong X, Arvan P, Lindberg I, Evans-Molina C
Diabetologia 2023 Nov;66(11):2042-2061. Epub 2023 Aug 4 doi: 10.1007/s00125-023-05979-4. PMID: 37537395 Free PMC Article

Associations of cord blood meta-inflammation and vitamin D with neurodevelopmental delay: A prospective birth cohort study in China.

Wang P, Wu L, Yin WJ, Tao RX, Zhang Y, Li PP, Jiang XM, Shao ZY, Zhu P
Front Immunol 2022;13:1078340. Epub 2023 Jan 4 doi: 10.3389/fimmu.2022.1078340. PMID: 36685522 Free PMC Article

Stress Cardiac Biomarkers, Cardiovascular and Renal Outcomes, and Response to Canagliflozin.

Circulating Bile Acid Profiles: A Need for Further Examination.

Qi L, Tian Y, Chen Y
J Clin Endocrinol Metab 2021 Oct 21;106(11):3093-3112. doi: 10.1210/clinem/dgab531. PMID: 34279029

Reduced microvascular hyperaemia in subjects at risk of developing type 2 (non-insulin-dependent) diabetes mellitus.

Jaap AJ, Hammersley MS, Shore AC, Tooke JE
Diabetologia 1994 Feb;37(2):214-6. doi: 10.1007/s001250050096. PMID: 8163058

See all (137)

Recent systematic reviews

Association between female circulating heavy metal concentration and abortion: a systematic review and meta-analysis.

Ren M, Wang L, Wen L, Chen J, Quan S, Shi X
Front Endocrinol (Lausanne) 2023;14:1216507. Epub 2023 Aug 29 doi: 10.3389/fendo.2023.1216507. PMID: 37711903 Free PMC Article

PCOS during the menopausal transition and after menopause: a systematic review and meta-analysis.

Millán-de-Meer M, Luque-Ramírez M, Nattero-Chávez L, Escobar-Morreale HF
Hum Reprod Update 2023 Nov 2;29(6):741-772. doi: 10.1093/humupd/dmad015. PMID: 37353908

The biology of human overfeeding: A systematic review.

Bray GA, Bouchard C
Obes Rev 2020 Sep;21(9):e13040. Epub 2020 Jun 8 doi: 10.1111/obr.13040. PMID: 32515127

See all (3)

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Abnormal circulating insulin concentration

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Clinical resources

Practice guidelines

Consumer resources

Reviews

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