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Abnormality of the adrenal glands

MedGen UID:
892577
•Concept ID:
C4021794
•
Anatomical Abnormality
Synonyms: Adrenal abnormalities; Adrenal gland disease; adrenal gland disease; adrenal gland disease or disorder; adrenal gland diseases; adrenal gland disorder; adrenal gland disorders; disease of adrenal gland; disease or disorder of adrenal gland; disorder of adrenal gland
 
HPO: HP:0000834
Monarch Initiative: MONDO:0005495

Definition

Abnormality of the adrenal glands, i.e., of the endocrine glands located at the top of the kindneys. [from HPO]

Professional guidelines

PubMed

Prenatal diagnosis of abdominal lymphatic malformations.
Liu YP, Huang YL, Tsai PS, Lin DC, Chen CP
Taiwan J Obstet Gynecol 2021 Jan;60(1):13-19. doi: 10.1016/j.tjog.2020.11.003. PMID: 33494985
Pathogenesis and treatment of primary aldosteronism.
Zennaro MC, Boulkroun S, Fernandes-Rosa FL
Nat Rev Endocrinol 2020 Oct;16(10):578-589. Epub 2020 Jul 28 doi: 10.1038/s41574-020-0382-4. PMID: 32724183
Sjogren's syndrome: An update on disease pathogenesis, clinical manifestations and treatment.
Vivino FB, Bunya VY, Massaro-Giordano G, Johr CR, Giattino SL, Schorpion A, Shafer B, Peck A, Sivils K, Rasmussen A, Chiorini JA, He J, Ambrus JL Jr
Clin Immunol 2019 Jun;203:81-121. Epub 2019 Apr 29 doi: 10.1016/j.clim.2019.04.009. PMID: 31022578

Recent clinical studies

Etiology

Congenital Adrenal Hyperplasia.
Fraga NR, Minaeian N, Kim MS
Pediatr Rev 2024 Feb 1;45(2):74-84. doi: 10.1542/pir.2022-005617. PMID: 38296783
Hypoglycaemia in adrenal insufficiency.
Lee SC, Baranowski ES, Sakremath R, Saraff V, Mohamed Z
Front Endocrinol (Lausanne) 2023;14:1198519. Epub 2023 Nov 20 doi: 10.3389/fendo.2023.1198519. PMID: 38053731Free PMC Article
X-linked adrenoleukodystrophy and primary adrenal insufficiency.
Cappa M, Todisco T, Bizzarri C
Front Endocrinol (Lausanne) 2023;14:1309053. Epub 2023 Nov 16 doi: 10.3389/fendo.2023.1309053. PMID: 38034003Free PMC Article
Major depressive disorder.
Otte C, Gold SM, Penninx BW, Pariante CM, Etkin A, Fava M, Mohr DC, Schatzberg AF
Nat Rev Dis Primers 2016 Sep 15;2:16065. doi: 10.1038/nrdp.2016.65. PMID: 27629598
Polycystic ovarian syndrome.
Khan KA, Stas S, Kurukulasuriya LR
J Cardiometab Syndr 2006 Spring;1(2):125-30; quiz 131-2. doi: 10.1111/j.1559-4564.2006.05675.x. PMID: 17679815

Diagnosis

Imaging of Adrenal-Related Endocrine Disorders.
Yalniz C, Morani AC, Waguespack SG, Elsayes KM
Radiol Clin North Am 2020 Nov;58(6):1099-1113. Epub 2020 Sep 17 doi: 10.1016/j.rcl.2020.07.010. PMID: 33040851
Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency.
Merke DP, Auchus RJ
N Engl J Med 2020 Sep 24;383(13):1248-1261. doi: 10.1056/NEJMra1909786. PMID: 32966723
Pathogenesis and treatment of primary aldosteronism.
Zennaro MC, Boulkroun S, Fernandes-Rosa FL
Nat Rev Endocrinol 2020 Oct;16(10):578-589. Epub 2020 Jul 28 doi: 10.1038/s41574-020-0382-4. PMID: 32724183
Major depressive disorder.
Otte C, Gold SM, Penninx BW, Pariante CM, Etkin A, Fava M, Mohr DC, Schatzberg AF
Nat Rev Dis Primers 2016 Sep 15;2:16065. doi: 10.1038/nrdp.2016.65. PMID: 27629598
Adrenal incidentaloma.
Gajraj H, Young AE
Br J Surg 1993 Apr;80(4):422-6. doi: 10.1002/bjs.1800800405. PMID: 8495301

Therapy

Congenital Adrenal Hyperplasia.
Fraga NR, Minaeian N, Kim MS
Pediatr Rev 2024 Feb 1;45(2):74-84. doi: 10.1542/pir.2022-005617. PMID: 38296783
Hypoglycaemia in adrenal insufficiency.
Lee SC, Baranowski ES, Sakremath R, Saraff V, Mohamed Z
Front Endocrinol (Lausanne) 2023;14:1198519. Epub 2023 Nov 20 doi: 10.3389/fendo.2023.1198519. PMID: 38053731Free PMC Article
X-linked adrenoleukodystrophy and primary adrenal insufficiency.
Cappa M, Todisco T, Bizzarri C
Front Endocrinol (Lausanne) 2023;14:1309053. Epub 2023 Nov 16 doi: 10.3389/fendo.2023.1309053. PMID: 38034003Free PMC Article
Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency.
Merke DP, Auchus RJ
N Engl J Med 2020 Sep 24;383(13):1248-1261. doi: 10.1056/NEJMra1909786. PMID: 32966723
Major depressive disorder.
Otte C, Gold SM, Penninx BW, Pariante CM, Etkin A, Fava M, Mohr DC, Schatzberg AF
Nat Rev Dis Primers 2016 Sep 15;2:16065. doi: 10.1038/nrdp.2016.65. PMID: 27629598

Prognosis

Pathophysiological interpretation of fetal heart rate tracings in clinical practice.
Jia YJ, Ghi T, Pereira S, Gracia Perez-Bonfils A, Chandraharan E
Am J Obstet Gynecol 2023 Jun;228(6):622-644. doi: 10.1016/j.ajog.2022.05.023. PMID: 37270259
Imaging of Adrenal-Related Endocrine Disorders.
Yalniz C, Morani AC, Waguespack SG, Elsayes KM
Radiol Clin North Am 2020 Nov;58(6):1099-1113. Epub 2020 Sep 17 doi: 10.1016/j.rcl.2020.07.010. PMID: 33040851
Carney complex.
Espiard S, Bertherat J
Front Horm Res 2013;41:50-62. Epub 2013 Mar 19 doi: 10.1159/000345669. PMID: 23652670
Adrenal vein sampling.
Kahn SL, Angle JF
Tech Vasc Interv Radiol 2010 Jun;13(2):110-25. doi: 10.1053/j.tvir.2010.02.006. PMID: 20540920
Paediatric laparoscopic surgery.
El-Ghoneimi A
Curr Opin Urol 2003 Jul;13(4):329-35. doi: 10.1097/00042307-200307000-00010. PMID: 12811298

Clinical prediction guides

X-linked adrenoleukodystrophy and primary adrenal insufficiency.
Cappa M, Todisco T, Bizzarri C
Front Endocrinol (Lausanne) 2023;14:1309053. Epub 2023 Nov 16 doi: 10.3389/fendo.2023.1309053. PMID: 38034003Free PMC Article
Pathophysiological interpretation of fetal heart rate tracings in clinical practice.
Jia YJ, Ghi T, Pereira S, Gracia Perez-Bonfils A, Chandraharan E
Am J Obstet Gynecol 2023 Jun;228(6):622-644. doi: 10.1016/j.ajog.2022.05.023. PMID: 37270259
Origin and initiation mechanisms of neuroblastoma.
Tsubota S, Kadomatsu K
Cell Tissue Res 2018 May;372(2):211-221. Epub 2018 Feb 14 doi: 10.1007/s00441-018-2796-z. PMID: 29445860
Carney complex.
Espiard S, Bertherat J
Front Horm Res 2013;41:50-62. Epub 2013 Mar 19 doi: 10.1159/000345669. PMID: 23652670
Adrenal vein sampling.
Kahn SL, Angle JF
Tech Vasc Interv Radiol 2010 Jun;13(2):110-25. doi: 10.1053/j.tvir.2010.02.006. PMID: 20540920

Recent systematic reviews

Adrenal Medullary Hyperplasia: A Systematic Review and Meta-analysis.
Ganni R, Torpy DJ, Falhammar H, Louise Rushworth R
J Clin Endocrinol Metab 2023 Aug 18;108(9):e885-e892. doi: 10.1210/clinem/dgad121. PMID: 36896586Free PMC Article
Ethnic and National Differences in Congenital Adrenal Hyperplasia Incidence: A Systematic Review and Meta-Analysis.
Navarro-Zambrana AN, Sheets LR
Horm Res Paediatr 2023;96(3):249-258. Epub 2022 Aug 16 doi: 10.1159/000526401. PMID: 35973409
Adrenal ectopy of adult groin region: a systematic review of an unexpected anatomopathologic diagnosis.
Senescende L, Bitolog PL, Auberger E, Zarzavadjian Le Bian A, Cesaretti M
Hernia 2016 Dec;20(6):879-885. Epub 2016 Sep 6 doi: 10.1007/s10029-016-1535-1. PMID: 27601037
Systematic review: diagnostic procedures to differentiate unilateral from bilateral adrenal abnormality in primary aldosteronism.
Kempers MJ, Lenders JW, van Outheusden L, van der Wilt GJ, Schultze Kool LJ, Hermus AR, Deinum J
Ann Intern Med 2009 Sep 1;151(5):329-37. doi: 10.7326/0003-4819-151-5-200909010-00007. PMID: 19721021
Exploration and management of adrenal incidentalomas. French Society of Endocrinology Consensus.
Tabarin A, Bardet S, Bertherat J, Dupas B, Chabre O, Hamoir E, Laurent F, Tenenbaum F, Cazalda M, Lefebvre H, Valli N, Rohmer V; French Society of Endocrinology Consensus
Ann Endocrinol (Paris) 2008 Dec;69(6):487-500. Epub 2008 Nov 20 doi: 10.1016/j.ando.2008.09.003. PMID: 19022420

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