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Pneumatosis Intestinalis

MedGen UID:
886640
•Concept ID:
C1112565
•
Sign or Symptom

Definition

The presence of gas within the wall of the large or small intestine. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPneumatosis Intestinalis

Professional guidelines

PubMed

Conservative Management of Pneumatosis Intestinalis and Portal Venous Gas After Pediatric Liver Transplantation.
Ryan JL, Dandridge LM, Andrews WS, Daniel JF, Fischer RT, Rivard DC, Wieser AB, Kane BJ, Hendrickson RJ
Transplant Proc 2020 Apr;52(3):938-942. Epub 2020 Feb 29 doi: 10.1016/j.transproceed.2020.01.010. PMID: 32122661
Clinical significance of pneumatosis intestinalis - correlation of MDCT-findings with treatment and outcome.
Treyaud MO, Duran R, Zins M, Knebel JF, Meuli RA, Schmidt S
Eur Radiol 2017 Jan;27(1):70-79. Epub 2016 Apr 22 doi: 10.1007/s00330-016-4348-9. PMID: 27106233Free PMC Article
Diagnosis and treatment of colonic disease in AIDS.
Mönkemüller KE, Wilcox CM
Gastrointest Endosc Clin N Am 1998 Oct;8(4):889-911. doi: 10.1016/S1052-5157(18)30238-1. PMID: 9730938Free PMC Article

Recent clinical studies

Etiology

An Update on Acute Mesenteric Ischemia.
Yu H, Kirkpatrick IDC
Can Assoc Radiol J 2023 Feb;74(1):160-171. Epub 2022 May 11 doi: 10.1177/08465371221094280. PMID: 35544414
Pneumatosis Intestinalis and Anorexia Nervosa.
Gibson D, Watters A, Pieracci F, Reiss R, Mehler PS
Surg Infect (Larchmt) 2022 Sep;23(7):661-666. Epub 2022 Aug 16 doi: 10.1089/sur.2022.127. PMID: 35969259
Value in palliative cancer surgery: A critical assessment.
Folkert IW, Roses RE
J Surg Oncol 2016 Sep;114(3):311-5. Epub 2016 Jul 8 doi: 10.1002/jso.24303. PMID: 27393738
Pneumatosis intestinalis: a review.
Heng Y, Schuffler MD, Haggitt RC, Rohrmann CA
Am J Gastroenterol 1995 Oct;90(10):1747-58. PMID: 7572888
Necrotizing enterocolitis.
Frantz ID 3rd, L'heureux P, Engel RR, Hunt CE
J Pediatr 1975 Feb;86(2):259-63. doi: 10.1016/s0022-3476(75)80485-9. PMID: 803385

Diagnosis

An Update on Acute Mesenteric Ischemia.
Yu H, Kirkpatrick IDC
Can Assoc Radiol J 2023 Feb;74(1):160-171. Epub 2022 May 11 doi: 10.1177/08465371221094280. PMID: 35544414
Pneumatosis Intestinalis and Anorexia Nervosa.
Gibson D, Watters A, Pieracci F, Reiss R, Mehler PS
Surg Infect (Larchmt) 2022 Sep;23(7):661-666. Epub 2022 Aug 16 doi: 10.1089/sur.2022.127. PMID: 35969259
Role of Abdominal US in Diagnosis of NEC.
Kim JH
Clin Perinatol 2019 Mar;46(1):119-127. Epub 2018 Dec 20 doi: 10.1016/j.clp.2018.10.006. PMID: 30771813
Radiological Evaluation of Bowel Ischemia.
Dhatt HS, Behr SC, Miracle A, Wang ZJ, Yeh BM
Radiol Clin North Am 2015 Nov;53(6):1241-54. doi: 10.1016/j.rcl.2015.06.009. PMID: 26526436Free PMC Article
Gastroduodenal emphysema.
D'Cruz R, Emil S
J Pediatr Surg 2008 Nov;43(11):2121-3. doi: 10.1016/j.jpedsurg.2008.07.019. PMID: 18970955

Therapy

Pneumatosis intestinalis in COVID-19.
Meini S, Zini C, Passaleva MT, Frullini A, Fusco F, Carpi R, Piani F
BMJ Open Gastroenterol 2020 Jun;7(1) doi: 10.1136/bmjgast-2020-000434. PMID: 32522754Free PMC Article
Pneumatosis Intestinalis After Molecular-Targeted Therapy.
Chaudhry NS, Bi WL, Gupta S, Keraliya A, Shimizu N, Chiocca EA
World Neurosurg 2019 May;125:312-315. Epub 2019 Feb 11 doi: 10.1016/j.wneu.2019.01.225. PMID: 30763745
Cancer therapy-related complications in the bowel and mesentery: an imaging perspective.
Gray EJ, Darvishzadeh A, Sharma A, Ganeshan D, Faria SC, Lall C
Abdom Radiol (NY) 2016 Oct;41(10):2031-47. doi: 10.1007/s00261-016-0799-3. PMID: 27277528
What next in necrotizing enterocolitis?
Yurdakök M
Turk J Pediatr 2008 Jan-Feb;50(1):1-11. PMID: 18365584
Necrotizing enterocolitis.
Frantz ID 3rd, L'heureux P, Engel RR, Hunt CE
J Pediatr 1975 Feb;86(2):259-63. doi: 10.1016/s0022-3476(75)80485-9. PMID: 803385

Prognosis

Pneumatosis intestinalis and porto-mesenteric venous gas: a multicenter study.
Della Seta M, Kloeckner R, Pinto Dos Santos D, Walter-Rittel TC, Hahn F, Henze J, Gropp A, Pratschke J, Hamm B, Geisel D, Auer TA
BMC Med Imaging 2021 Aug 24;21(1):129. doi: 10.1186/s12880-021-00651-y. PMID: 34429069Free PMC Article
Value in palliative cancer surgery: A critical assessment.
Folkert IW, Roses RE
J Surg Oncol 2016 Sep;114(3):311-5. Epub 2016 Jul 8 doi: 10.1002/jso.24303. PMID: 27393738
Pneumatosis intestinalis with a focus on hyperbaric oxygen therapy.
Feuerstein JD, White N, Berzin TM
Mayo Clin Proc 2014 May;89(5):697-703. doi: 10.1016/j.mayocp.2014.01.026. PMID: 24797647
Pneumatosis intestinalis.
Saul T, Palamidessi N
J Emerg Med 2011 May;40(5):545-6. Epub 2009 Mar 9 doi: 10.1016/j.jemermed.2008.10.019. PMID: 19272737
Necrotizing enterocolitis.
Frantz ID 3rd, L'heureux P, Engel RR, Hunt CE
J Pediatr 1975 Feb;86(2):259-63. doi: 10.1016/s0022-3476(75)80485-9. PMID: 803385

Clinical prediction guides

Pneumatosis intestinalis and porto-mesenteric venous gas: a multicenter study.
Della Seta M, Kloeckner R, Pinto Dos Santos D, Walter-Rittel TC, Hahn F, Henze J, Gropp A, Pratschke J, Hamm B, Geisel D, Auer TA
BMC Med Imaging 2021 Aug 24;21(1):129. doi: 10.1186/s12880-021-00651-y. PMID: 34429069Free PMC Article
Machine learning for the prediction of pathologic pneumatosis intestinalis.
Clancy K, Dadashzadeh ER, Handzel R, Rieser C, Moses JB, Rosenblum L, Wu S
Surgery 2021 Sep;170(3):797-805. Epub 2021 Apr 27 doi: 10.1016/j.surg.2021.03.049. PMID: 33926706Free PMC Article
Clinical characteristics of patients with pneumatosis intestinalis.
Fujii M, Yamashita S, Tashiro J, Tanaka M, Takenaka Y, Yamasaki K, Masaki Y
ANZ J Surg 2021 Sep;91(9):1826-1831. Epub 2021 Apr 6 doi: 10.1111/ans.16772. PMID: 33825311
Pneumatosis intestinalis in COVID-19.
Meini S, Zini C, Passaleva MT, Frullini A, Fusco F, Carpi R, Piani F
BMJ Open Gastroenterol 2020 Jun;7(1) doi: 10.1136/bmjgast-2020-000434. PMID: 32522754Free PMC Article
Pneumatosis intestinalis with a focus on hyperbaric oxygen therapy.
Feuerstein JD, White N, Berzin TM
Mayo Clin Proc 2014 May;89(5):697-703. doi: 10.1016/j.mayocp.2014.01.026. PMID: 24797647

Recent systematic reviews

Radiological predictive factors of transmural intestinal necrosis in acute mesenteric ischemia: systematic review and meta-analysis.
Zeng Y, Yang F, Hu X, Zhu F, Chen W, Lin W
Eur Radiol 2023 Apr;33(4):2792-2799. Epub 2022 Nov 30 doi: 10.1007/s00330-022-09258-5. PMID: 36449058
Gastrointestinal Dysfunction Criteria in Critically Ill Children: The PODIUM Consensus Conference.
Typpo KV, Irving SY, Prince JM, Pathan N, Brown AM; Pediatric Organ Dysfunction Information Update Mandate (PODIUM) Collaborative
Pediatrics 2022 Jan 1;149(1 Suppl 1):S53-S58. doi: 10.1542/peds.2021-052888H. PMID: 34970680Free PMC Article
Abdominal imaging findings in patients with SARS-CoV-2 infection: a scoping review.
Lui K, Wilson MP, Low G
Abdom Radiol (NY) 2021 Mar;46(3):1249-1255. Epub 2020 Sep 14 doi: 10.1007/s00261-020-02739-5. PMID: 32926211Free PMC Article
Bowel ultrasound for predicting surgical management of necrotizing enterocolitis: a systematic review and meta-analysis.
Cuna AC, Reddy N, Robinson AL, Chan SS
Pediatr Radiol 2018 May;48(5):658-666. Epub 2017 Dec 19 doi: 10.1007/s00247-017-4056-x. PMID: 29260286Free PMC Article

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