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Obesity Related Glomerulopathy

MedGen UID:
884256
Concept ID:
C4054325
Disease or Syndrome

Definition

Diffuse glomerular (greater than 50% of glomeruli) hypertrophy (greater than 250 micron diameter) that occurs in the context of obesity. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVObesity Related Glomerulopathy

Professional guidelines

PubMed

Sandino J, Martín-Taboada M, Medina-Gómez G, Vila-Bedmar R, Morales E
Nutrients 2022 Sep 22;14(19) doi: 10.3390/nu14193937. PMID: 36235590Free PMC Article
Herman-Edelstein M, Weinstein T, Chagnac A
Semin Nephrol 2021 Jul;41(4):358-370. doi: 10.1016/j.semnephrol.2021.06.007. PMID: 34715965
Xu T, Sheng Z, Yao L
Front Med 2017 Sep;11(3):340-348. Epub 2017 Aug 8 doi: 10.1007/s11684-017-0570-3. PMID: 28791668

Recent clinical studies

Etiology

Nehus E, Mitsnefes M
Pediatr Clin North Am 2019 Feb;66(1):31-43. doi: 10.1016/j.pcl.2018.08.004. PMID: 30454749
Xu T, Sheng Z, Yao L
Front Med 2017 Sep;11(3):340-348. Epub 2017 Aug 8 doi: 10.1007/s11684-017-0570-3. PMID: 28791668
Sikorska D, Grzymislawska M, Roszak M, Gulbicka P, Korybalska K, Witowski J
J Physiol Pharmacol 2017 Apr;68(2):175-180. PMID: 28614766
Snyder S, Turner GA, Turner A
Prim Care 2014 Dec;41(4):875-93. Epub 2014 Oct 3 doi: 10.1016/j.pop.2014.08.008. PMID: 25439539
Tsuboi N, Utsunomiya Y, Hosoya T
Nephrol Dial Transplant 2013 Nov;28 Suppl 4:iv108-13. Epub 2013 Jul 17 doi: 10.1093/ndt/gft258. PMID: 23868145

Diagnosis

Martínez-Montoro JI, Morales E, Cornejo-Pareja I, Tinahones FJ, Fernández-García JC
Obes Rev 2022 Jul;23(7):e13450. Epub 2022 Apr 1 doi: 10.1111/obr.13450. PMID: 35362662Free PMC Article
Nehus E, Mitsnefes M
Pediatr Clin North Am 2019 Feb;66(1):31-43. doi: 10.1016/j.pcl.2018.08.004. PMID: 30454749
Xu T, Sheng Z, Yao L
Front Med 2017 Sep;11(3):340-348. Epub 2017 Aug 8 doi: 10.1007/s11684-017-0570-3. PMID: 28791668
Sikorska D, Grzymislawska M, Roszak M, Gulbicka P, Korybalska K, Witowski J
J Physiol Pharmacol 2017 Apr;68(2):175-180. PMID: 28614766
D'Agati VD, Chagnac A, de Vries AP, Levi M, Porrini E, Herman-Edelstein M, Praga M
Nat Rev Nephrol 2016 Aug;12(8):453-71. Epub 2016 Jun 6 doi: 10.1038/nrneph.2016.75. PMID: 27263398

Therapy

Jakhotia S, Kavvuri R, Raviraj S, Baishya S, Pasupulati AK, Reddy GB
Int J Obes (Lond) 2024 Aug;48(8):1080-1091. Epub 2024 Mar 19 doi: 10.1038/s41366-024-01509-3. PMID: 38504059
Martínez-Montoro JI, Morales E, Cornejo-Pareja I, Tinahones FJ, Fernández-García JC
Obes Rev 2022 Jul;23(7):e13450. Epub 2022 Apr 1 doi: 10.1111/obr.13450. PMID: 35362662Free PMC Article
Wang AY, Kovesdy CP
Contrib Nephrol 2021;199:24-42. Epub 2021 Aug 3 doi: 10.1159/000517669. PMID: 34343991
Shen WW, Chen HM, Chen H, Xu F, Li LS, Liu ZH
Clin J Am Soc Nephrol 2010 Aug;5(8):1401-9. Epub 2010 May 24 doi: 10.2215/CJN.01370210. PMID: 20498244Free PMC Article
Ahmed MH
Expert Opin Emerg Drugs 2006 Nov;11(4):563-5. doi: 10.1517/14728214.11.4.563. PMID: 17064218

Prognosis

Wang AY, Kovesdy CP
Contrib Nephrol 2021;199:24-42. Epub 2021 Aug 3 doi: 10.1159/000517669. PMID: 34343991
Zhang J, Wang Y, Liu Z, Huang B, Wang X, Xie M, Yu D, Guo R, Wang P
Clin Exp Nephrol 2021 Aug;25(8):865-874. Epub 2021 Apr 2 doi: 10.1007/s10157-021-02045-4. PMID: 33811270
Sikorska D, Grzymislawska M, Roszak M, Gulbicka P, Korybalska K, Witowski J
J Physiol Pharmacol 2017 Apr;68(2):175-180. PMID: 28614766
Kovesdy CP, Furth S, Zoccali C; World Kidney Day Steering Committee
Physiol Int 2017 Mar 1;104(1):1-14. doi: 10.1556/2060.104.2017.1.9. PMID: 28361575
Kanasaki K, Kitada M, Kanasaki M, Koya D
Nephrol Dial Transplant 2013 Nov;28 Suppl 4:iv1-7. Epub 2013 Jun 5 doi: 10.1093/ndt/gft098. PMID: 23743020

Clinical prediction guides

Christoffersen BØ, Kristensen CA, Lindgaard R, Kirk RK, Viuff BM, Kvist PH, Pedersen HD, Ludvigsen TP, Skovgaard T, Fels JJ, Martinussen T, Christiansen LB, Cirera S, Olsen LH
Sci Rep 2023 Apr 12;13(1):6017. doi: 10.1038/s41598-023-32674-6. PMID: 37045950Free PMC Article
Sandino J, Martín-Taboada M, Medina-Gómez G, Vila-Bedmar R, Morales E
Nutrients 2022 Sep 22;14(19) doi: 10.3390/nu14193937. PMID: 36235590Free PMC Article
Tsuboi N, Okabayashi Y
Semin Nephrol 2021 Jul;41(4):296-306. doi: 10.1016/j.semnephrol.2021.06.002. PMID: 34715960
Wang AY, Kovesdy CP
Contrib Nephrol 2021;199:24-42. Epub 2021 Aug 3 doi: 10.1159/000517669. PMID: 34343991
Xu X, Huang X, Zhang L, Huang X, Qin Z, Hua F
BMC Nephrol 2021 Jun 10;22(1):218. doi: 10.1186/s12882-021-02391-1. PMID: 34107901Free PMC Article

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