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Microcystic/reticular schwannoma

MedGen UID:
882329
•Concept ID:
C4054526
•
Neoplastic Process
Synonyms: Microcystic reticular schwannoma; Microcystic/Reticular Schwannoma; microcystic/reticular schwannoma
SNOMED CT: Microcystic reticular schwannoma (1287273003); Microcystic/reticular schwannoma (1295254003)
 
Monarch Initiative: MONDO:0002556

Definition

The rarest histopathologic subtype of Schwannoma. The reported cases have been located in the gastrointestinal submucosa or subcutaneous tissue. Morphologically it is characterized by the presence of a microcyst-rich network of spindle cells with minimal amount of cytoplasm and Antoni A tissue. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMicrocystic/reticular schwannoma

Recent clinical studies

Etiology

Cutaneous microcystic/reticular schwannoma: case report and literature review of an exceedingly rare entity with an unusual presentation.
Georgescu TA, Dumitru AV, Oproiu AM, Nica AE, Costache D, Pătraşcu OM, Lăzăroiu AM, Chefani AE, Sajin M, Costache M
Rom J Morphol Embryol 2018;59(1):303-309. PMID: 29940642
Cutaneous microcystic/reticular schwannoma: a poorly recognized entity.
Luzar B, Tanaka M, Schneider J, Calonje E
J Cutan Pathol 2016 Feb;43(2):93-100. Epub 2015 Dec 7 doi: 10.1111/cup.12624. PMID: 26350054
Microcystic/Reticular Schwannoma of the Mandible First Case Report and Review of the Literature.
Yin Y, Wang T, Cai YP, Huang XJ, Li YJ, Chen SH, Qin R, Wang CF, Wu Q
Medicine (Baltimore) 2015 Nov;94(45):e1974. doi: 10.1097/MD.0000000000001974. PMID: 26559274Free PMC Article

Diagnosis

Lumbar intraspinal microcystic/reticular schwannoma: Case report and literature review.
Liu C, Yan L, Liu Q, Li J, Jin H, Wang J, Deng Y
Medicine (Baltimore) 2018 Sep;97(39):e12474. doi: 10.1097/MD.0000000000012474. PMID: 30278533Free PMC Article
Microcystic/Reticular Schwannoma of the Mandible First Case Report and Review of the Literature.
Yin Y, Wang T, Cai YP, Huang XJ, Li YJ, Chen SH, Qin R, Wang CF, Wu Q
Medicine (Baltimore) 2015 Nov;94(45):e1974. doi: 10.1097/MD.0000000000001974. PMID: 26559274Free PMC Article
Primary adrenal microcystic/reticular schwannoma: clinicopathological and immunohistochemical studies of an extremely rare case.
Zhou J, Zhang D, Wang G, Li W, Xu J, Ma Y, Zhang J, Li Z, Zhao Z
Int J Clin Exp Pathol 2015;8(5):5808-11. Epub 2015 May 1 PMID: 26191302Free PMC Article
Microcystic/reticular schwannoma of the esophagus: the first case report and a diagnostic pitfall.
Gu MJ, Choi JH
BMC Gastroenterol 2014 Nov 18;14:193. doi: 10.1186/s12876-014-0193-y. PMID: 25404099Free PMC Article
Bowel mesentery (meso-appendix) microcystic/reticular schwannoma: case report and literature review.
Tang SX, Sun YH, Zhou XR, Wang J
World J Gastroenterol 2014 Feb 7;20(5):1371-6. doi: 10.3748/wjg.v20.i5.1371. PMID: 24574814Free PMC Article

Therapy

Microcystic/reticular schwannoma of the pancreas: a potential diagnostic pitfall.
Liegl B, Bodo K, Martin D, Tsybrovskyy O, Lackner K, Beham A
Pathol Int 2011 Feb;61(2):88-92. Epub 2010 Nov 15 doi: 10.1111/j.1440-1827.2010.02614.x. PMID: 21255185

Prognosis

Primary adrenal microcystic/reticular schwannoma: clinicopathological and immunohistochemical studies of an extremely rare case.
Zhou J, Zhang D, Wang G, Li W, Xu J, Ma Y, Zhang J, Li Z, Zhao Z
Int J Clin Exp Pathol 2015;8(5):5808-11. Epub 2015 May 1 PMID: 26191302Free PMC Article
Microcystic/reticular schwannoma of the esophagus: the first case report and a diagnostic pitfall.
Gu MJ, Choi JH
BMC Gastroenterol 2014 Nov 18;14:193. doi: 10.1186/s12876-014-0193-y. PMID: 25404099Free PMC Article
Microcystic/reticular schwannoma of the pancreas: a potential diagnostic pitfall.
Liegl B, Bodo K, Martin D, Tsybrovskyy O, Lackner K, Beham A
Pathol Int 2011 Feb;61(2):88-92. Epub 2010 Nov 15 doi: 10.1111/j.1440-1827.2010.02614.x. PMID: 21255185

Clinical prediction guides

Lumbar intraspinal microcystic/reticular schwannoma: Case report and literature review.
Liu C, Yan L, Liu Q, Li J, Jin H, Wang J, Deng Y
Medicine (Baltimore) 2018 Sep;97(39):e12474. doi: 10.1097/MD.0000000000012474. PMID: 30278533Free PMC Article
Cutaneous microcystic/reticular schwannoma: a poorly recognized entity.
Luzar B, Tanaka M, Schneider J, Calonje E
J Cutan Pathol 2016 Feb;43(2):93-100. Epub 2015 Dec 7 doi: 10.1111/cup.12624. PMID: 26350054
Microcystic/Reticular Schwannoma of the Mandible First Case Report and Review of the Literature.
Yin Y, Wang T, Cai YP, Huang XJ, Li YJ, Chen SH, Qin R, Wang CF, Wu Q
Medicine (Baltimore) 2015 Nov;94(45):e1974. doi: 10.1097/MD.0000000000001974. PMID: 26559274Free PMC Article
Primary adrenal microcystic/reticular schwannoma: clinicopathological and immunohistochemical studies of an extremely rare case.
Zhou J, Zhang D, Wang G, Li W, Xu J, Ma Y, Zhang J, Li Z, Zhao Z
Int J Clin Exp Pathol 2015;8(5):5808-11. Epub 2015 May 1 PMID: 26191302Free PMC Article
Microcystic/reticular schwannoma of the pancreas: a potential diagnostic pitfall.
Liegl B, Bodo K, Martin D, Tsybrovskyy O, Lackner K, Beham A
Pathol Int 2011 Feb;61(2):88-92. Epub 2010 Nov 15 doi: 10.1111/j.1440-1827.2010.02614.x. PMID: 21255185

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