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Fatty atrophy

MedGen UID:
87173
•Concept ID:
C0333650
•
Pathologic Function
Synonyms: Adipose Tissue Atrophy; Adipositas ex vacuo; Fat Atrophy; Fat atrophy
SNOMED CT: Fatty atrophy (42335002); Adipositas ex vacuo (42335002); Fat atrophy (42335002)

Definition

Shrinking of adipose tissue. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFatty atrophy

Professional guidelines

PubMed

The Anatomical Course of the Superior Gluteal Nerve With Regard to the Direct Anterior Approach for Primary and Revision Total Hip Arthroplasty.
Starke V, Stofferin H, Mannschatz S, Hörmann R, Dammerer D, Thaler M
J Arthroplasty 2021 Mar;36(3):1138-1142. Epub 2020 Oct 1 doi: 10.1016/j.arth.2020.09.045. PMID: 33071031
The pathogenesis and management of cuff tear arthropathy.
Rugg CM, Gallo RA, Craig EV, Feeley BT
J Shoulder Elbow Surg 2018 Dec;27(12):2271-2283. Epub 2018 Sep 26 doi: 10.1016/j.jse.2018.07.020. PMID: 30268586

Recent clinical studies

Etiology

Entrapment Neuropathies of the Shoulder.
Alaia EF, Day MS, Alaia MJ
Semin Musculoskelet Radiol 2022 Apr;26(2):114-122. Epub 2022 May 24 doi: 10.1055/s-0042-1742752. PMID: 35609573
Healing and Functional Results of Dermal Allograft Augmentation of Complex and Revision Rotator Cuff Repairs.
Namdari S, Nicholson T, Brolin TJ, Lu J, Abboud JA, Lazarus MD
Am J Sports Med 2021 Jul;49(8):2042-2047. Epub 2021 May 20 doi: 10.1177/03635465211015194. PMID: 34015245
Correlation between multifidus fatty atrophy and lumbar disc degeneration in low back pain.
Faur C, Patrascu JM, Haragus H, Anglitoiu B
BMC Musculoskelet Disord 2019 Sep 5;20(1):414. doi: 10.1186/s12891-019-2786-7. PMID: 31488112Free PMC Article
Efficacy of Imaging Modalities Assessing Fatty Infiltration in Rotator Cuff Tears.
Tenbrunsel TN, Whaley JD, Golchian D, Malone DL, Lima DJL, Sabesan VJ
JBJS Rev 2019 Apr;7(4):e3. doi: 10.2106/JBJS.RVW.18.00042. PMID: 30969180
The metabolic syndrome and the heart--a considered opinion.
Leichman JG, Lavis VR, Aguilar D, Wilson CR, Taegtmeyer H
Clin Res Cardiol 2006 Jan;95 Suppl 1:i134-41. doi: 10.1007/s00392-006-1119-7. PMID: 16598541

Diagnosis

Rotator Cuff Injury and Repair.
Fitzpatrick LA, Atinga A, White L, Henry PDG, Probyn L
Semin Musculoskelet Radiol 2022 Oct;26(5):585-596. Epub 2022 Dec 19 doi: 10.1055/s-0042-1756167. PMID: 36535594
LRSAM1 and the RING domain: Charcot-Marie-Tooth disease and beyond.
Palaima P, Berciano J, Peeters K, Jordanova A
Orphanet J Rare Dis 2021 Feb 10;16(1):74. doi: 10.1186/s13023-020-01654-8. PMID: 33568173Free PMC Article
Hip Gluteus Medius and Minimus Endoscopic Treatment Results in Patient Satisfaction.
Lubowitz JH, Brand JC, Rossi MJ
Arthroscopy 2020 Nov;36(11):2775-2776. doi: 10.1016/j.arthro.2020.09.030. PMID: 33172572
Correlation between multifidus fatty atrophy and lumbar disc degeneration in low back pain.
Faur C, Patrascu JM, Haragus H, Anglitoiu B
BMC Musculoskelet Disord 2019 Sep 5;20(1):414. doi: 10.1186/s12891-019-2786-7. PMID: 31488112Free PMC Article
Efficacy of Imaging Modalities Assessing Fatty Infiltration in Rotator Cuff Tears.
Tenbrunsel TN, Whaley JD, Golchian D, Malone DL, Lima DJL, Sabesan VJ
JBJS Rev 2019 Apr;7(4):e3. doi: 10.2106/JBJS.RVW.18.00042. PMID: 30969180

Therapy

MRI Findings of Muscle Damage after Total Hip Arthroplasty Using the Complete Muscle Preserving Anterolateral Supine Approach.
Oda S, Hisatome T, Cho E, Fujimaki H, Nakanishi K
Medicina (Kaunas) 2022 May 26;58(6) doi: 10.3390/medicina58060713. PMID: 35743976Free PMC Article
Incidence of tensor fascia lata muscle atrophy after using the modified Watson-Jones anterolateral approach in total hip arthroplasty.
Takada R, Jinno T, Miyatake K, Hirao M, Yoshii T, Okawa A
Eur J Orthop Surg Traumatol 2021 Apr;31(3):533-540. Epub 2020 Oct 10 doi: 10.1007/s00590-020-02806-z. PMID: 33040212
Assessment of hip abductors by MRI after total hip arthroplasty and effect of fatty atrophy on functional outcome.
Kovalak E, Özdemir H, Ermutlu C, Obut A
Acta Orthop Traumatol Turc 2018 May;52(3):196-200. Epub 2018 Feb 23 doi: 10.1016/j.aott.2017.10.005. PMID: 29478777Free PMC Article
Gluteal muscle fatty atrophy is not associated with elevated blood metal ions or pseudotumors in patients with a unilateral metal-on-metal hip replacement.
Reito A, Elo P, Nieminen J, Puolakka T, Eskelinen A
Acta Orthop 2016 Feb;87(1):29-35. Epub 2015 Oct 1 doi: 10.3109/17453674.2015.1094713. PMID: 26427902Free PMC Article
Biologic and pharmacologic augmentation of rotator cuff repairs.
Edwards SL, Lynch TS, Saltzman MD, Terry MA, Nuber GW
J Am Acad Orthop Surg 2011 Oct;19(10):583-9. doi: 10.5435/00124635-201110000-00002. PMID: 21980023

Prognosis

Novel 3D MRI-based volumetric assessment of rotator cuff musculature demonstrates stronger correlation with preoperative functional status when compared to the Goutallier grading scheme.
DeFoor MT, Riem L, Cognetti DJ, Cousins M, DuCharme O, Feng X, Blemker SS, Antosh IJ, Cote MP, Werner BC, Sheean AJ
J Shoulder Elbow Surg 2024 Nov;33(11):e575-e584. Epub 2024 Apr 10 doi: 10.1016/j.jse.2024.02.043. PMID: 38604396Free PMC Article
Entrapment Neuropathies of the Shoulder.
Alaia EF, Day MS, Alaia MJ
Semin Musculoskelet Radiol 2022 Apr;26(2):114-122. Epub 2022 May 24 doi: 10.1055/s-0042-1742752. PMID: 35609573
Outcomes Following Double-Row and Medial Double-Pulley Rotator Cuff Repair.
Noyes MP, Denard PJ
Orthopedics 2021 Jan 1;44(1):e125-e130. Epub 2020 Oct 1 doi: 10.3928/01477447-20200925-01. PMID: 33002184
Efficacy of Imaging Modalities Assessing Fatty Infiltration in Rotator Cuff Tears.
Tenbrunsel TN, Whaley JD, Golchian D, Malone DL, Lima DJL, Sabesan VJ
JBJS Rev 2019 Apr;7(4):e3. doi: 10.2106/JBJS.RVW.18.00042. PMID: 30969180
Gluteal muscle fatty atrophy is not associated with elevated blood metal ions or pseudotumors in patients with a unilateral metal-on-metal hip replacement.
Reito A, Elo P, Nieminen J, Puolakka T, Eskelinen A
Acta Orthop 2016 Feb;87(1):29-35. Epub 2015 Oct 1 doi: 10.3109/17453674.2015.1094713. PMID: 26427902Free PMC Article

Clinical prediction guides

Primary Cuff Repair Augmented With a Balloon Spacer in a Large and Massive Rotator Cuff Tear Series: A Technique and Short-term Outcome and Imaging Study.
Wong SJ, Lie HM, Bin Massuryono MD, Wong NHP, Lie DTT
Orthopedics 2025 Jan-Feb;48(1):e56-e61. Epub 2024 Dec 3 doi: 10.3928/01477447-20241127-04. PMID: 39622069
Lower trapezius transfer for massive posterosuperior rotator cuff defects.
Rodríguez-Vaquero G, López-Fernández V, Calvo E
Oper Orthop Traumatol 2022 Feb;34(1):34-44. Epub 2021 Dec 16 doi: 10.1007/s00064-021-00756-1. PMID: 34918172
Hip Gluteus Medius and Minimus Endoscopic Treatment Results in Patient Satisfaction.
Lubowitz JH, Brand JC, Rossi MJ
Arthroscopy 2020 Nov;36(11):2775-2776. doi: 10.1016/j.arthro.2020.09.030. PMID: 33172572
Correlation between multifidus fatty atrophy and lumbar disc degeneration in low back pain.
Faur C, Patrascu JM, Haragus H, Anglitoiu B
BMC Musculoskelet Disord 2019 Sep 5;20(1):414. doi: 10.1186/s12891-019-2786-7. PMID: 31488112Free PMC Article
Efficacy of Imaging Modalities Assessing Fatty Infiltration in Rotator Cuff Tears.
Tenbrunsel TN, Whaley JD, Golchian D, Malone DL, Lima DJL, Sabesan VJ
JBJS Rev 2019 Apr;7(4):e3. doi: 10.2106/JBJS.RVW.18.00042. PMID: 30969180

Recent systematic reviews

Efficacy of Imaging Modalities Assessing Fatty Infiltration in Rotator Cuff Tears.
Tenbrunsel TN, Whaley JD, Golchian D, Malone DL, Lima DJL, Sabesan VJ
JBJS Rev 2019 Apr;7(4):e3. doi: 10.2106/JBJS.RVW.18.00042. PMID: 30969180

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