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Retroperitoneal paraganglioma

MedGen UID:
870539
Concept ID:
C4024987
Neoplastic Process
Synonym: Retroperitoneal chemodectomas
 
HPO: HP:0006729

Definition

A paraganglioma (previously referred to as chemodectoma) located in the retroperitoneal space. Paragangliomas (also known as extra-adrenal pheochromocytomas) are rare tumors that arise from extra-adrenal chromaffin cells. Paragangliomas are characterized by secretions of excessive catecholamines, including epinephrine, norepinephrine and dopamine, which may lead to clinical symptoms, including episodic hypertension, tachycardia and diaphoresis. However, between 40 and 50% of paragangliomas are non-functional. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRetroperitoneal paraganglioma

Professional guidelines

PubMed

Improta L, Tzanis D, Bouhadiba T, Abdelhafidh K, Bonvalot S
Eur J Surg Oncol 2020 Sep;46(9):1573-1579. Epub 2020 May 21 doi: 10.1016/j.ejso.2020.04.054. PMID: 32600897
Trans-Atlantic RPS Working Group
Ann Surg Oncol 2016 Oct;23(11):3531-3540. Epub 2016 Aug 1 doi: 10.1245/s10434-016-5336-7. PMID: 27480354Free PMC Article
Strauss DC, Hayes AJ, Thomas JM
Ann R Coll Surg Engl 2011 May;93(4):275-80. doi: 10.1308/003588411X571944. PMID: 21944791Free PMC Article

Recent clinical studies

Etiology

Chun C, Song L, Xu G, Shi Q, Li F, Jia X
J Surg Oncol 2024 Jul;130(1):47-55. Epub 2024 Jun 12 doi: 10.1002/jso.27681. PMID: 38864273
Sultan S, Barrett N, Curran S, Hynes N
BMJ Case Rep 2020 Jun 17;13(6) doi: 10.1136/bcr-2019-233371. PMID: 32554461Free PMC Article
Jawad Z, Fajardo-Puerta AB, Lefroy D, Todd J, Lim PB, Jiao LR
Ann R Coll Surg Engl 2017 May;99(5):e148-e150. doi: 10.1308/rcsann.2017.0056. PMID: 28462638Free PMC Article
Akdamar MK, Eltoum I, Eloubeidi MA
Gastrointest Endosc 2004 Dec;60(6):1018-21. doi: 10.1016/s0016-5107(04)02218-7. PMID: 15605027
Hamilton MA, Tait D
Br J Radiol 2000 Aug;73(872):901-4. doi: 10.1259/bjr.73.872.11026870. PMID: 11026870

Diagnosis

Cai PY, Golan R, Yanke B
Urology 2018 Dec;122:24-27. Epub 2018 Aug 16 doi: 10.1016/j.urology.2018.07.031. PMID: 30121193
Ota S, Ueoka H, Tanimoto M
Lancet 2003 Oct 18;362(9392):1266. doi: 10.1016/S0140-6736(03)14569-2. PMID: 14575970
Barfield R, Hill DA, Hoffer FA, Tekautz T, Spunt SL
Med Pediatr Oncol 2002 Aug;39(2):120-4. doi: 10.1002/mpo.10099. PMID: 12116060
Butterworth JE
Urology 1975 Jul;6(1):131. doi: 10.1016/0090-4295(75)90615-9. PMID: 1145918
Anderson CB, Ward S, Lee J, Rosai J
Am Surg 1974 Nov;40(11):636-42. PMID: 4374105

Therapy

Yang Y, Wang G, Lu H, Liu Y, Ning S, Luo F
BMC Surg 2020 Nov 30;20(1):304. doi: 10.1186/s12893-020-00953-y. PMID: 33256692Free PMC Article
Tong A, Li M, Cui Y, Ma X, Wang H, Li Y
Front Endocrinol (Lausanne) 2020;11:61. Epub 2020 Feb 18 doi: 10.3389/fendo.2020.00061. PMID: 32132978Free PMC Article
Acosta-Mérida MA, Silvestre-Rodríguez J, Hernández-Ramírez JM, Godoy C, Marchena-Gómez J
Cir Esp (Engl Ed) 2020 Jun-Jul;98(6):362-364. Epub 2019 Nov 18 doi: 10.1016/j.ciresp.2019.09.007. PMID: 31753286
Cai PY, Golan R, Yanke B
Urology 2018 Dec;122:24-27. Epub 2018 Aug 16 doi: 10.1016/j.urology.2018.07.031. PMID: 30121193
Akdamar MK, Eltoum I, Eloubeidi MA
Gastrointest Endosc 2004 Dec;60(6):1018-21. doi: 10.1016/s0016-5107(04)02218-7. PMID: 15605027

Prognosis

Chun C, Song L, Xu G, Shi Q, Li F, Jia X
J Surg Oncol 2024 Jul;130(1):47-55. Epub 2024 Jun 12 doi: 10.1002/jso.27681. PMID: 38864273
Yang Y, Wang G, Lu H, Liu Y, Ning S, Luo F
BMC Surg 2020 Nov 30;20(1):304. doi: 10.1186/s12893-020-00953-y. PMID: 33256692Free PMC Article
Ahmad S, Cathy D, Sheikh M, Sweeney P
Ir J Med Sci 2009 Jun;178(2):211-4. Epub 2008 Jan 9 doi: 10.1007/s11845-007-0113-z. PMID: 18183473
Cunningham SC, Suh HS, Winter JM, Montgomery E, Schulick RD, Cameron JL, Yeo CJ
J Gastrointest Surg 2006 Sep-Oct;10(8):1156-63. doi: 10.1016/j.gassur.2006.05.004. PMID: 16966036
Hamilton MA, Tait D
Br J Radiol 2000 Aug;73(872):901-4. doi: 10.1259/bjr.73.872.11026870. PMID: 11026870

Clinical prediction guides

Chun C, Song L, Xu G, Shi Q, Li F, Jia X
J Surg Oncol 2024 Jul;130(1):47-55. Epub 2024 Jun 12 doi: 10.1002/jso.27681. PMID: 38864273
Ziani I, Ibrahimi A, Bellouki O, Zouidia F, El Sayegh H, Benslimane L, Nouini Y
Pan Afr Med J 2023;44:39. Epub 2023 Jan 19 doi: 10.11604/pamj.2023.44.39.24768. PMID: 37034483Free PMC Article
Yang Y, Wang G, Lu H, Liu Y, Ning S, Luo F
BMC Surg 2020 Nov 30;20(1):304. doi: 10.1186/s12893-020-00953-y. PMID: 33256692Free PMC Article
Buonuomo V, Ruggiero A, Rando G, D'Urzo C, Manzoni C, Pintus C
Pediatr Hematol Oncol 2004 Dec;21(8):731-8. doi: 10.1080/08880010490515029. PMID: 15739629
Anderson-Ramcharan A, Khan J, Ping AC, Harnarayan C
West Indian Med J 2000 Mar;49(1):76-8. PMID: 10786462

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