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Necrotizing myopathy

MedGen UID:
870175
•Concept ID:
C4024608
•
Disease or Syndrome
HPO: HP:0008978

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNecrotizing myopathy

Professional guidelines

PubMed

Management of immune-mediated necrotizing myopathy.
Suh J, Amato AA
Muscle Nerve 2024 Aug;70(2):166-172. Epub 2024 May 27 doi: 10.1002/mus.28114. PMID: 38801022
Current Classification and Management of Inflammatory Myopathies.
Schmidt J
J Neuromuscul Dis 2018;5(2):109-129. doi: 10.3233/JND-180308. PMID: 29865091Free PMC Article
Current diagnosis and treatment of polymyositis and dermatomyositis.
Sasaki H, Kohsaka H
Mod Rheumatol 2018 Nov;28(6):913-921. Epub 2018 May 9 doi: 10.1080/14397595.2018.1467257. PMID: 29669460

Recent clinical studies

Etiology

Clinical pearls and promising therapies in myositis.
Connolly CM, Paik JJ
Expert Rev Clin Immunol 2023 Jul-Dec;19(7):797-811. Epub 2023 May 18 doi: 10.1080/1744666X.2023.2212162. PMID: 37158055Free PMC Article
Statins Neuromuscular Adverse Effects.
Attardo S, Musumeci O, Velardo D, Toscano A
Int J Mol Sci 2022 Jul 28;23(15) doi: 10.3390/ijms23158364. PMID: 35955495Free PMC Article
Idiopathic inflammatory myopathies.
Lundberg IE, Fujimoto M, Vencovsky J, Aggarwal R, Holmqvist M, Christopher-Stine L, Mammen AL, Miller FW
Nat Rev Dis Primers 2021 Dec 2;7(1):86. doi: 10.1038/s41572-021-00321-x. PMID: 34857798
Immune-mediated necrotizing myopathy: clinical features and pathogenesis.
Allenbach Y, Benveniste O, Stenzel W, Boyer O
Nat Rev Rheumatol 2020 Dec;16(12):689-701. Epub 2020 Oct 22 doi: 10.1038/s41584-020-00515-9. PMID: 33093664
Inclusion body myositis.
Dimachkie MM, Barohn RJ
Neurol Clin 2014 Aug;32(3):629-46, vii. Epub 2014 Jun 6 doi: 10.1016/j.ncl.2014.04.001. PMID: 25037082Free PMC Article

Diagnosis

Idiopathic inflammatory myopathies.
Lundberg IE, Fujimoto M, Vencovsky J, Aggarwal R, Holmqvist M, Christopher-Stine L, Mammen AL, Miller FW
Nat Rev Dis Primers 2021 Dec 2;7(1):86. doi: 10.1038/s41572-021-00321-x. PMID: 34857798
Immune-mediated necrotizing myopathy: clinical features and pathogenesis.
Allenbach Y, Benveniste O, Stenzel W, Boyer O
Nat Rev Rheumatol 2020 Dec;16(12):689-701. Epub 2020 Oct 22 doi: 10.1038/s41584-020-00515-9. PMID: 33093664
Classification of idiopathic inflammatory myopathies: pathology perspectives.
Tanboon J, Nishino I
Curr Opin Neurol 2019 Oct;32(5):704-714. doi: 10.1097/WCO.0000000000000740. PMID: 31369423
Current Classification and Management of Inflammatory Myopathies.
Schmidt J
J Neuromuscul Dis 2018;5(2):109-129. doi: 10.3233/JND-180308. PMID: 29865091Free PMC Article
Inclusion body myositis.
Dimachkie MM, Barohn RJ
Neurol Clin 2014 Aug;32(3):629-46, vii. Epub 2014 Jun 6 doi: 10.1016/j.ncl.2014.04.001. PMID: 25037082Free PMC Article

Therapy

Allogeneic CD19-targeted CAR-T therapy in patients with severe myositis and systemic sclerosis.
Wang X, Wu X, Tan B, Zhu L, Zhang Y, Lin L, Xiao Y, Sun A, Wan X, Liu S, Liu Y, Ta N, Zhang H, Song J, Li T, Zhou L, Yin J, Ye L, Lu H, Hong J, Cheng H, Wang P, Li W, Chen J, Zhang J, Luo J, Huang M, Guo L, Pan X, Jin Y, Ye W, Dai L, Zhu J, Sun L, Zheng B, Li D, He Y, Liu M, Wu H, Du B, Xu H
Cell 2024 Sep 5;187(18):4890-4904.e9. Epub 2024 Jul 15 doi: 10.1016/j.cell.2024.06.027. PMID: 39013470
Management of immune-mediated necrotizing myopathy.
Suh J, Amato AA
Muscle Nerve 2024 Aug;70(2):166-172. Epub 2024 May 27 doi: 10.1002/mus.28114. PMID: 38801022
Statins Neuromuscular Adverse Effects.
Attardo S, Musumeci O, Velardo D, Toscano A
Int J Mol Sci 2022 Jul 28;23(15) doi: 10.3390/ijms23158364. PMID: 35955495Free PMC Article
Immune-mediated necrotizing myopathy: clinical features and pathogenesis.
Allenbach Y, Benveniste O, Stenzel W, Boyer O
Nat Rev Rheumatol 2020 Dec;16(12):689-701. Epub 2020 Oct 22 doi: 10.1038/s41584-020-00515-9. PMID: 33093664
Anti-HMGCR Myopathy.
Mohassel P, Mammen AL
J Neuromuscul Dis 2018;5(1):11-20. doi: 10.3233/JND-170282. PMID: 29480216Free PMC Article

Prognosis

Clinical pearls and promising therapies in myositis.
Connolly CM, Paik JJ
Expert Rev Clin Immunol 2023 Jul-Dec;19(7):797-811. Epub 2023 May 18 doi: 10.1080/1744666X.2023.2212162. PMID: 37158055Free PMC Article
Idiopathic inflammatory myopathies.
Lundberg IE, Fujimoto M, Vencovsky J, Aggarwal R, Holmqvist M, Christopher-Stine L, Mammen AL, Miller FW
Nat Rev Dis Primers 2021 Dec 2;7(1):86. doi: 10.1038/s41572-021-00321-x. PMID: 34857798
Immune-mediated necrotizing myopathy: clinical features and pathogenesis.
Allenbach Y, Benveniste O, Stenzel W, Boyer O
Nat Rev Rheumatol 2020 Dec;16(12):689-701. Epub 2020 Oct 22 doi: 10.1038/s41584-020-00515-9. PMID: 33093664
Current Classification and Management of Inflammatory Myopathies.
Schmidt J
J Neuromuscul Dis 2018;5(2):109-129. doi: 10.3233/JND-180308. PMID: 29865091Free PMC Article
Inclusion body myositis.
Dimachkie MM, Barohn RJ
Neurol Clin 2014 Aug;32(3):629-46, vii. Epub 2014 Jun 6 doi: 10.1016/j.ncl.2014.04.001. PMID: 25037082Free PMC Article

Clinical prediction guides

Allogeneic CD19-targeted CAR-T therapy in patients with severe myositis and systemic sclerosis.
Wang X, Wu X, Tan B, Zhu L, Zhang Y, Lin L, Xiao Y, Sun A, Wan X, Liu S, Liu Y, Ta N, Zhang H, Song J, Li T, Zhou L, Yin J, Ye L, Lu H, Hong J, Cheng H, Wang P, Li W, Chen J, Zhang J, Luo J, Huang M, Guo L, Pan X, Jin Y, Ye W, Dai L, Zhu J, Sun L, Zheng B, Li D, He Y, Liu M, Wu H, Du B, Xu H
Cell 2024 Sep 5;187(18):4890-4904.e9. Epub 2024 Jul 15 doi: 10.1016/j.cell.2024.06.027. PMID: 39013470
Management of immune-mediated necrotizing myopathy.
Suh J, Amato AA
Muscle Nerve 2024 Aug;70(2):166-172. Epub 2024 May 27 doi: 10.1002/mus.28114. PMID: 38801022
Clinical pearls and promising therapies in myositis.
Connolly CM, Paik JJ
Expert Rev Clin Immunol 2023 Jul-Dec;19(7):797-811. Epub 2023 May 18 doi: 10.1080/1744666X.2023.2212162. PMID: 37158055Free PMC Article
Statins Neuromuscular Adverse Effects.
Attardo S, Musumeci O, Velardo D, Toscano A
Int J Mol Sci 2022 Jul 28;23(15) doi: 10.3390/ijms23158364. PMID: 35955495Free PMC Article
Immune-mediated necrotizing myopathy (IMNM): A myopathological challenge.
Merlonghi G, Antonini G, Garibaldi M
Autoimmun Rev 2022 Feb;21(2):102993. Epub 2021 Nov 16 doi: 10.1016/j.autrev.2021.102993. PMID: 34798316

Recent systematic reviews

Rituximab Treatment in Adult Patients With Idiopathic Inflammatory Myositis: A Systematic Review and Meta-analysis.
Rojas LO, Ramsubeik K, Sanchez-Ramos L, Motilal S, Singh JA, Kaeley GS
J Clin Rheumatol 2025 Jan 1;31(1):33-39. Epub 2024 Nov 11 doi: 10.1097/RHU.0000000000002151. PMID: 39527803
Inflammatory myopathy following coronavirus disease 2019 vaccination: A systematic review.
Ding Y, Ge Y
Front Public Health 2022;10:1007637. Epub 2022 Oct 21 doi: 10.3389/fpubh.2022.1007637. PMID: 36339243Free PMC Article
Physical therapy in adult inflammatory myopathy patients: a systematic review.
Van Thillo A, Vulsteke JB, Van Assche D, Verschueren P, De Langhe E
Clin Rheumatol 2019 Aug;38(8):2039-2051. Epub 2019 May 21 doi: 10.1007/s10067-019-04571-9. PMID: 31115788
Statin-Associated Autoimmune Myopathy: A Systematic Review of 100 Cases.
Nazir S, Lohani S, Tachamo N, Poudel D, Donato A
J Clin Rheumatol 2017 Apr;23(3):149-154. doi: 10.1097/RHU.0000000000000497. PMID: 28277343
Statins as a possible cause of inflammatory and necrotizing myopathies.
Padala S, Thompson PD
Atherosclerosis 2012 May;222(1):15-21. Epub 2011 Nov 16 doi: 10.1016/j.atherosclerosis.2011.11.005. PMID: 22154355

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