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Abnormality of ocular abduction

MedGen UID:
868990
•Concept ID:
C4023405
•
Anatomical Abnormality
HPO: HP:0011347

Definition

An abnormality involving the movement of the eye outwards. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormality of ocular abduction

Professional guidelines

PubMed

Molecular genetic screening of MBS1 locus on chromosome 13 for microdeletions and exclusion of FGF9, GSH1 and CDX2 as causative genes in patients with Moebius syndrome.
Uzumcu A, Karaman B, Toksoy G, Uyguner ZO, Candan S, Eris H, Tatli B, Geckinli B, Yuksel A, Kayserili H, Basaran S
Eur J Med Genet 2009 Sep-Oct;52(5):315-20. Epub 2009 May 19 doi: 10.1016/j.ejmg.2009.05.003. PMID: 19460469

Recent clinical studies

Etiology

Clinical and imaging features of idiopathic intracranial hypertension.
Wang Z, Yang J, Liao X, Xie N, Luo M, Tian Y, Yao L, Hu Y, Yi F, Zhou Y, Zhou L, Xu H, Sun Q
Zhong Nan Da Xue Xue Bao Yi Xue Ban 2021 Nov 28;46(11):1241-1250. doi: 10.11817/j.issn.1672-7347.2021.200907. PMID: 34911859Free PMC Article
Augmented superior rectus muscle transposition in management of defective ocular abduction.
Farid MF, Daifalla AEM, Awwad MA
BMC Ophthalmol 2021 Jan 20;21(1):50. doi: 10.1186/s12886-020-01779-1. PMID: 33472581Free PMC Article
Long-term outcomes of strabismus surgery in Mobius sequence.
Lueder GT, Galli M
Strabismus 2019 Jun;27(2):43-46. Epub 2019 Apr 8 doi: 10.1080/09273972.2019.1599402. PMID: 30958093
Characterization of ocular motor deficits in congenital facial weakness: Moebius and related syndromes.
Rucker JC, Webb BD, Frempong T, Gaspar H, Naidich TP, Jabs EW
Brain 2014 Apr;137(Pt 4):1068-79. Epub 2014 Feb 21 doi: 10.1093/brain/awu021. PMID: 24561559Free PMC Article
Möbius and Möbius-like syndromes (TTV-OFM, OMLH).
Miller MT, Ray V, Owens P, Chen F
J Pediatr Ophthalmol Strabismus 1989 Jul-Aug;26(4):176-88. doi: 10.3928/0191-3913-19890701-07. PMID: 2668494

Diagnosis

Update on the medial longitudinal fasciculus syndrome.
Lee SH, Kim JM, Kim JS
Neurol Sci 2022 Jun;43(6):3533-3540. Epub 2022 Mar 8 doi: 10.1007/s10072-022-05967-3. PMID: 35258687
The Eye Examination in the Evaluation of Child Abuse.
Christian CW, Levin AV; COUNCIL ON CHILD ABUSE AND NEGLECT; SECTION ON OPHTHALMOLOGY; AMERICAN ASSOCIATION OF CERTIFIED ORTHOPTISTS; AMERICAN ASSOCIATION FOR PEDIATRIC OPHTHALMOLOGY AND STRABISMUS; AMERICAN ACADEMY OF OPHTHALMOLOGY
Pediatrics 2018 Aug;142(2) doi: 10.1542/peds.2018-1411. PMID: 30037976
Variable synergistic divergence.
Kim JH, Hwang JM
Optom Vis Sci 2009 Dec;86(12):1386-8. doi: 10.1097/OPX.0b013e3181be9db3. PMID: 19826317
Neuropsychiatric findings of Möbius sequence -- a review.
Briegel W
Clin Genet 2006 Aug;70(2):91-7. doi: 10.1111/j.1399-0004.2006.00649.x. PMID: 16879188
Duane retraction syndrome.
Alexandrakis G, Saunders RA
Ophthalmol Clin North Am 2001 Sep;14(3):407-17. doi: 10.1016/s0896-1549(05)70238-8. PMID: 11705140

Therapy

Ocular motility changes after inferomedial wall and balanced medial plus lateral wall orbital decompression in Graves' orbitopathy: a randomized prospective comparative study.
Leite CA, Pereira TS, Chiang J, Moritz RB, Gonçalves ACP, Monteiro MLR
Clinics (Sao Paulo) 2021;76:e2592. Epub 2021 Apr 9 doi: 10.6061/clinics/2021/e2592. PMID: 33852655Free PMC Article
Clinical Course of Sarcoidosis in World Trade Center-Exposed Firefighters.
Hena KM, Yip J, Jaber N, Goldfarb D, Fullam K, Cleven K, Moir W, Zeig-Owens R, Webber MP, Spevack DM, Judson MA, Maier L, Krumerman A, Aizer A, Spivack SD, Berman J, Aldrich TK, Prezant DJ; FDNY Sarcoidosis Clinical Research Group*
Chest 2018 Jan;153(1):114-123. Epub 2017 Oct 21 doi: 10.1016/j.chest.2017.10.014. PMID: 29066387Free PMC Article
Ocular motor features of alternating hemiplegia of childhood.
Egan RA
J Neuroophthalmol 2002 Jun;22(2):99-101. doi: 10.1097/00041327-200206000-00007. PMID: 12131468
Sarin poisoning on Tokyo subway.
Ohbu S, Yamashina A, Takasu N, Yamaguchi T, Murai T, Nakano K, Matsui Y, Mikami R, Sakurai K, Hinohara S
South Med J 1997 Jun;90(6):587-93. doi: 10.1097/00007611-199706000-00002. PMID: 9191733
Ocular motility in thalidomide embryopathy.
Miller MT, Strömland K
J Pediatr Ophthalmol Strabismus 1991 Jan-Feb;28(1):47-54. PMID: 2019959

Prognosis

Surgical outcomes following strabismus surgery for abducens nerve palsy.
O'Brien JC, Melson AT, Bryant JC, Ding K, Farris BK, Siatkowski RM
J AAPOS 2023 Jun;27(3):142.e1-142.e6. Epub 2023 May 11 doi: 10.1016/j.jaapos.2023.04.003. PMID: 37179001
Motility of the Ocular Prosthesis in Anophthalmic Patients: Objective and Patient-perceived Findings.
van Renterghem V, Ruiters S, Mombaerts I
Orbit 2023 Aug;42(4):383-388. Epub 2022 Aug 4 doi: 10.1080/01676830.2022.2107687. PMID: 35924421
Augmented lateral rectus muscle recession for treatment of infantile exotropia.
Huang L, Li N
Int Ophthalmol 2022 May;42(5):1589-1594. Epub 2022 Jan 29 doi: 10.1007/s10792-021-02152-x. PMID: 35091974
Long-term outcomes of strabismus surgery in Mobius sequence.
Lueder GT, Galli M
Strabismus 2019 Jun;27(2):43-46. Epub 2019 Apr 8 doi: 10.1080/09273972.2019.1599402. PMID: 30958093
Clinical Course of Sarcoidosis in World Trade Center-Exposed Firefighters.
Hena KM, Yip J, Jaber N, Goldfarb D, Fullam K, Cleven K, Moir W, Zeig-Owens R, Webber MP, Spevack DM, Judson MA, Maier L, Krumerman A, Aizer A, Spivack SD, Berman J, Aldrich TK, Prezant DJ; FDNY Sarcoidosis Clinical Research Group*
Chest 2018 Jan;153(1):114-123. Epub 2017 Oct 21 doi: 10.1016/j.chest.2017.10.014. PMID: 29066387Free PMC Article

Clinical prediction guides

Motility of the Ocular Prosthesis in Anophthalmic Patients: Objective and Patient-perceived Findings.
van Renterghem V, Ruiters S, Mombaerts I
Orbit 2023 Aug;42(4):383-388. Epub 2022 Aug 4 doi: 10.1080/01676830.2022.2107687. PMID: 35924421
Update on the medial longitudinal fasciculus syndrome.
Lee SH, Kim JM, Kim JS
Neurol Sci 2022 Jun;43(6):3533-3540. Epub 2022 Mar 8 doi: 10.1007/s10072-022-05967-3. PMID: 35258687
Long-term outcomes of strabismus surgery in Mobius sequence.
Lueder GT, Galli M
Strabismus 2019 Jun;27(2):43-46. Epub 2019 Apr 8 doi: 10.1080/09273972.2019.1599402. PMID: 30958093
Neuro-ophthalmic manifestations of the syndrome of ophthalmoplegia, ataxia and areflexia: a review.
al-Din SN, Anderson M, Eeg-Olofsson O, Trontelj JV
Acta Neurol Scand 1994 Mar;89(3):157-63. doi: 10.1111/j.1600-0404.1994.tb01654.x. PMID: 8030396
Möbius and Möbius-like syndromes (TTV-OFM, OMLH).
Miller MT, Ray V, Owens P, Chen F
J Pediatr Ophthalmol Strabismus 1989 Jul-Aug;26(4):176-88. doi: 10.3928/0191-3913-19890701-07. PMID: 2668494

Recent systematic reviews

Retinal hemorrhage and bleeding disorders in children: A review.
Thau A, Saffren B, Zakrzewski H, Anderst JD, Carpenter SL, Levin A
Child Abuse Negl 2021 Feb;112:104901. Epub 2021 Jan 2 doi: 10.1016/j.chiabu.2020.104901. PMID: 33401159

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