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Abnormal number of granulocyte precursors

MedGen UID:
868629
•Concept ID:
C4023029
•
Anatomical Abnormality
HPO: HP:0012137

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal number of granulocyte precursors

Recent clinical studies

Etiology

Glial injury in neurotoxicity after pediatric CD19-directed chimeric antigen receptor T cell therapy.
Gust J, Finney OC, Li D, Brakke HM, Hicks RM, Futrell RB, Gamble DN, Rawlings-Rhea SD, Khalatbari HK, Ishak GE, Duncan VE, Hevner RF, Jensen MC, Park JR, Gardner RA
Ann Neurol 2019 Jul;86(1):42-54. Epub 2019 May 27 doi: 10.1002/ana.25502. PMID: 31074527Free PMC Article
The impact of several phenotypic features at diagnosis on survival of patients with myelodysplastic syndromes.
Reis-Alves SC, Traina F, Saad ST, Metze K, Lorand-Metze I
Neoplasma 2010;57(6):530-6. doi: 10.4149/neo_2010_06_530. PMID: 20845991
Spontaneous improvement of hematologic abnormalities in patients having juvenile myelomonocytic leukemia with specific RAS mutations.
Matsuda K, Shimada A, Yoshida N, Ogawa A, Watanabe A, Yajima S, Iizuka S, Koike K, Yanai F, Kawasaki K, Yanagimachi M, Kikuchi A, Ohtsuka Y, Hidaka E, Yamauchi K, Tanaka M, Yanagisawa R, Nakazawa Y, Shiohara M, Manabe A, Kojima S, Koike K
Blood 2007 Jun 15;109(12):5477-80. Epub 2007 Mar 1 doi: 10.1182/blood-2006-09-046649. PMID: 17332249
Expression and functional role of urokinase-type plasminogen activator receptor in normal and acute leukaemic cells.
Lanza F, Castoldi GL, Castagnari B, Todd RF 3rd, Moretti S, Spisani S, Latorraca A, Focarile E, Roberti MG, Traniello S
Br J Haematol 1998 Oct;103(1):110-23. doi: 10.1046/j.1365-2141.1998.00932.x. PMID: 9792297
The myelodysplastic syndromes.
Masey JA
Br J Biomed Sci 1997 Mar;54(1):65-70. PMID: 9167309

Diagnosis

Glial injury in neurotoxicity after pediatric CD19-directed chimeric antigen receptor T cell therapy.
Gust J, Finney OC, Li D, Brakke HM, Hicks RM, Futrell RB, Gamble DN, Rawlings-Rhea SD, Khalatbari HK, Ishak GE, Duncan VE, Hevner RF, Jensen MC, Park JR, Gardner RA
Ann Neurol 2019 Jul;86(1):42-54. Epub 2019 May 27 doi: 10.1002/ana.25502. PMID: 31074527Free PMC Article
The impact of several phenotypic features at diagnosis on survival of patients with myelodysplastic syndromes.
Reis-Alves SC, Traina F, Saad ST, Metze K, Lorand-Metze I
Neoplasma 2010;57(6):530-6. doi: 10.4149/neo_2010_06_530. PMID: 20845991
The immunophenotype of different immature, myeloid and B-cell lineage-committed CD34+ hematopoietic cells allows discrimination between normal/reactive and myelodysplastic syndrome precursors.
Matarraz S, López A, Barrena S, Fernandez C, Jensen E, Flores J, Bárcena P, Rasillo A, Sayagues JM, Sánchez ML, Hernandez-Campo P, Hernandez Rivas JM, Salvador C, Fernandez-Mosteirín N, Giralt M, Perdiguer L, Orfao A
Leukemia 2008 Jun;22(6):1175-83. Epub 2008 Mar 13 doi: 10.1038/leu.2008.49. PMID: 18337765
Clinical manifestation of myeloperoxidase deficiency.
Lanza F
J Mol Med (Berl) 1998 Sep;76(10):676-81. doi: 10.1007/s001090050267. PMID: 9766845
The myelodysplastic syndromes.
Masey JA
Br J Biomed Sci 1997 Mar;54(1):65-70. PMID: 9167309

Therapy

PROGNOSIS OF THE COURSE OF CHORNOBYL-ORIGINATED ACUTE LYMPHOBLASTIC LEUKEMIA IN CHILDREN IN UKRAINE DEPENDING ON THE REASON OF STANDARD CHEMOTHERAPY INTERRUPTION.
Bebeshko VG, Bruslova KM, Tsvetkova NM, Lyashenko LO, Pushkariova TI, Gonchar LO, Tryhlib IV, Yatsemirskyi SM, Samson YM, Boyarskyi VG, Grischenko KV, Polyanska VM, Dmytrenko IV
Probl Radiac Med Radiobiol 2019 Dec;24:335-349. doi: 10.33145/2304-8336-2019-24-335-349. PMID: 31841478
Glial injury in neurotoxicity after pediatric CD19-directed chimeric antigen receptor T cell therapy.
Gust J, Finney OC, Li D, Brakke HM, Hicks RM, Futrell RB, Gamble DN, Rawlings-Rhea SD, Khalatbari HK, Ishak GE, Duncan VE, Hevner RF, Jensen MC, Park JR, Gardner RA
Ann Neurol 2019 Jul;86(1):42-54. Epub 2019 May 27 doi: 10.1002/ana.25502. PMID: 31074527Free PMC Article
Abnormalities of erythropoiesis during HIV-1 disease: a longitudinal analysis.
Costantini A, Giuliodoro S, Butini L, Silvestri G, Leoni P, Montroni M
J Acquir Immune Defic Syndr 2009 Sep 1;52(1):70-4. doi: 10.1097/QAI.0b013e3181af65c5. PMID: 19574926
Perturbation of autocrine/paracrine loops of burst-forming units of erythroid-derived cells in rHuEPO-hyporesponsive hemodialysis patients.
Nakao K, Wada J, Ota K, Ichikawa H, Akagi S, Okamoto A, Hida K, Nagake Y, Makino H
Am J Kidney Dis 2003 Mar;41(3):624-36. doi: 10.1053/ajkd.2003.50124. PMID: 12612986
The hematopoietic effects of lithium.
Boggs DR, Joyce RA
Semin Hematol 1983 Apr;20(2):129-38. PMID: 6348956

Prognosis

PROGNOSIS OF THE COURSE OF CHORNOBYL-ORIGINATED ACUTE LYMPHOBLASTIC LEUKEMIA IN CHILDREN IN UKRAINE DEPENDING ON THE REASON OF STANDARD CHEMOTHERAPY INTERRUPTION.
Bebeshko VG, Bruslova KM, Tsvetkova NM, Lyashenko LO, Pushkariova TI, Gonchar LO, Tryhlib IV, Yatsemirskyi SM, Samson YM, Boyarskyi VG, Grischenko KV, Polyanska VM, Dmytrenko IV
Probl Radiac Med Radiobiol 2019 Dec;24:335-349. doi: 10.33145/2304-8336-2019-24-335-349. PMID: 31841478
The impact of several phenotypic features at diagnosis on survival of patients with myelodysplastic syndromes.
Reis-Alves SC, Traina F, Saad ST, Metze K, Lorand-Metze I
Neoplasma 2010;57(6):530-6. doi: 10.4149/neo_2010_06_530. PMID: 20845991
The immunophenotype of different immature, myeloid and B-cell lineage-committed CD34+ hematopoietic cells allows discrimination between normal/reactive and myelodysplastic syndrome precursors.
Matarraz S, López A, Barrena S, Fernandez C, Jensen E, Flores J, Bárcena P, Rasillo A, Sayagues JM, Sánchez ML, Hernandez-Campo P, Hernandez Rivas JM, Salvador C, Fernandez-Mosteirín N, Giralt M, Perdiguer L, Orfao A
Leukemia 2008 Jun;22(6):1175-83. Epub 2008 Mar 13 doi: 10.1038/leu.2008.49. PMID: 18337765
Spontaneous improvement of hematologic abnormalities in patients having juvenile myelomonocytic leukemia with specific RAS mutations.
Matsuda K, Shimada A, Yoshida N, Ogawa A, Watanabe A, Yajima S, Iizuka S, Koike K, Yanai F, Kawasaki K, Yanagimachi M, Kikuchi A, Ohtsuka Y, Hidaka E, Yamauchi K, Tanaka M, Yanagisawa R, Nakazawa Y, Shiohara M, Manabe A, Kojima S, Koike K
Blood 2007 Jun 15;109(12):5477-80. Epub 2007 Mar 1 doi: 10.1182/blood-2006-09-046649. PMID: 17332249
Expression and functional role of urokinase-type plasminogen activator receptor in normal and acute leukaemic cells.
Lanza F, Castoldi GL, Castagnari B, Todd RF 3rd, Moretti S, Spisani S, Latorraca A, Focarile E, Roberti MG, Traniello S
Br J Haematol 1998 Oct;103(1):110-23. doi: 10.1046/j.1365-2141.1998.00932.x. PMID: 9792297

Clinical prediction guides

Glial injury in neurotoxicity after pediatric CD19-directed chimeric antigen receptor T cell therapy.
Gust J, Finney OC, Li D, Brakke HM, Hicks RM, Futrell RB, Gamble DN, Rawlings-Rhea SD, Khalatbari HK, Ishak GE, Duncan VE, Hevner RF, Jensen MC, Park JR, Gardner RA
Ann Neurol 2019 Jul;86(1):42-54. Epub 2019 May 27 doi: 10.1002/ana.25502. PMID: 31074527Free PMC Article
Acute myeloid leukemia (AML-M2) with translocation (8;21) (q22;q22) and abnormal eosinophilic precursors in the bone marrow--a case report.
Gupta O, Aggarwal R, Prasad R
Indian J Pediatr 2012 Feb;79(2):256-9. Epub 2011 Jun 1 doi: 10.1007/s12098-011-0481-2. PMID: 21630067
Clinical manifestation of myeloperoxidase deficiency.
Lanza F
J Mol Med (Berl) 1998 Sep;76(10):676-81. doi: 10.1007/s001090050267. PMID: 9766845
Granulopoietic precursors in chronic neutropenia.
Niskanen E, Phillips SL, Hess CE
Scand J Haematol 1984 Nov;33(5):405-9. doi: 10.1111/j.1600-0609.1984.tb00717.x. PMID: 6515324
The hematopoietic effects of lithium.
Boggs DR, Joyce RA
Semin Hematol 1983 Apr;20(2):129-38. PMID: 6348956

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