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Hypoplastic vertebral pedicle

MedGen UID:
868149
•Concept ID:
C4022540
•
Anatomical Abnormality
HPO: HP:0030278

Definition

Underdeveloped vertebral pedicle. [from HPO]

Professional guidelines

PubMed

Preoperative diagnosis and management of the hypoplastic vessel syndrome.
Ameli FM, Hoy F
J Cardiovasc Surg (Torino) 1983 Nov-Dec;24(6):654-7. PMID: 6654979

Recent clinical studies

Etiology

Cerebrovascular Variants and the Role of the Selfish Brain in Young-Onset Hypertension.
Manghat NE, Robinson E, Mitrousi K, Rodrigues JCL, Hinton T, Paton JFR, Wise RG, Nightingale AK, Hart EC
Hypertension 2022 Jun;79(6):1265-1274. Epub 2022 Mar 16 doi: 10.1161/HYPERTENSIONAHA.121.18612. PMID: 35291807Free PMC Article
The position of the vertebral artery V1 segment relative to the C7 vertebra.
Ushiku C, Soshi S, Inoue T, Shinohara A, Shinohara K, Ohkawa A, Marumo K
J Orthop Sci 2021 Mar;26(2):203-206. Epub 2020 Apr 30 doi: 10.1016/j.jos.2020.03.020. PMID: 32360078
Vertebral abnormality without spine-curvature deformity on prenatal ultrasonography: sonographic findings and postnatal radiographic correlations.
Song MJ, Kim YH
J Med Ultrason (2001) 2018 Jan;45(1):89-95. Epub 2017 Apr 25 doi: 10.1007/s10396-017-0790-9. PMID: 28444475
CT volumetry of lumbar vertebral bodies in patients with hypoplasia L5 and bilateral spondylolysis and in normal controls.
Wilms GE, Willems E, Demaerel P, De Keyzer F
Neuroradiology 2012 Aug;54(8):839-43. Epub 2012 Apr 13 doi: 10.1007/s00234-012-1035-7. PMID: 22527686
Spondylolysis and isthmic spondylolisthesis: impact of vertebral hypoplasia on the use of the Meyerding classification.
Niggemann P, Kuchta J, Grosskurth D, Beyer HK, Hoeffer J, Delank KS
Br J Radiol 2012 Apr;85(1012):358-62. Epub 2011 Jul 12 doi: 10.1259/bjr/60355971. PMID: 21750127Free PMC Article

Diagnosis

Cerebrovascular Variants and the Role of the Selfish Brain in Young-Onset Hypertension.
Manghat NE, Robinson E, Mitrousi K, Rodrigues JCL, Hinton T, Paton JFR, Wise RG, Nightingale AK, Hart EC
Hypertension 2022 Jun;79(6):1265-1274. Epub 2022 Mar 16 doi: 10.1161/HYPERTENSIONAHA.121.18612. PMID: 35291807Free PMC Article
Vertebral abnormality without spine-curvature deformity on prenatal ultrasonography: sonographic findings and postnatal radiographic correlations.
Song MJ, Kim YH
J Med Ultrason (2001) 2018 Jan;45(1):89-95. Epub 2017 Apr 25 doi: 10.1007/s10396-017-0790-9. PMID: 28444475
Infantile developmental thoracolumbar kyphosis with segmental subluxation of the spine: report of five patients and review of the literature.
Ganesan S, Karampalis C, Garrido E, Tsirikos AI
Bone Joint J 2015 Jul;97-B(7):982-7. doi: 10.1302/0301-620X.97B7.35665. PMID: 26130356
Monochorionic monoamniotic twins: neonatal outcome.
Cordero L, Franco A, Joy SD
J Perinatol 2006 Mar;26(3):170-5. doi: 10.1038/sj.jp.7211457. PMID: 16467856
Preoperative diagnosis and management of the hypoplastic vessel syndrome.
Ameli FM, Hoy F
J Cardiovasc Surg (Torino) 1983 Nov-Dec;24(6):654-7. PMID: 6654979

Therapy

Spondylolysis and isthmic spondylolisthesis: impact of vertebral hypoplasia on the use of the Meyerding classification.
Niggemann P, Kuchta J, Grosskurth D, Beyer HK, Hoeffer J, Delank KS
Br J Radiol 2012 Apr;85(1012):358-62. Epub 2011 Jul 12 doi: 10.1259/bjr/60355971. PMID: 21750127Free PMC Article
Use of axial and subaxial translaminar screw fixation in the management of upper cervical spinal instability in a series of 7 children.
Chamoun RB, Relyea KM, Johnson KK, Whitehead WE, Curry DJ, Luerssen TG, Drake JM, Jea A
Neurosurgery 2009 Apr;64(4):734-9; discussion 739. doi: 10.1227/01.NEU.0000338950.46195.9C. PMID: 19349831

Prognosis

Cerebrovascular Variants and the Role of the Selfish Brain in Young-Onset Hypertension.
Manghat NE, Robinson E, Mitrousi K, Rodrigues JCL, Hinton T, Paton JFR, Wise RG, Nightingale AK, Hart EC
Hypertension 2022 Jun;79(6):1265-1274. Epub 2022 Mar 16 doi: 10.1161/HYPERTENSIONAHA.121.18612. PMID: 35291807Free PMC Article
The position of the vertebral artery V1 segment relative to the C7 vertebra.
Ushiku C, Soshi S, Inoue T, Shinohara A, Shinohara K, Ohkawa A, Marumo K
J Orthop Sci 2021 Mar;26(2):203-206. Epub 2020 Apr 30 doi: 10.1016/j.jos.2020.03.020. PMID: 32360078
Spondylolysis and isthmic spondylolisthesis: impact of vertebral hypoplasia on the use of the Meyerding classification.
Niggemann P, Kuchta J, Grosskurth D, Beyer HK, Hoeffer J, Delank KS
Br J Radiol 2012 Apr;85(1012):358-62. Epub 2011 Jul 12 doi: 10.1259/bjr/60355971. PMID: 21750127Free PMC Article
Monochorionic monoamniotic twins: neonatal outcome.
Cordero L, Franco A, Joy SD
J Perinatol 2006 Mar;26(3):170-5. doi: 10.1038/sj.jp.7211457. PMID: 16467856
Acquired degenerative changes of the intervertebral segments at and suprajacent to the lumbosacral junction. A radioanatomic analysis of the nondiskal structures of the spinal column and perispinal soft tissues.
Jinkins JR
Radiol Clin North Am 2001 Jan;39(1):73-99. doi: 10.1016/s0033-8389(05)70264-5. PMID: 11221507

Clinical prediction guides

Characteristics of Scoliosis in Mice Induced by Chondrocyte-specific Inactivation of L-type Amino Acid Transporter 1.
Handa M, Demura S, Yokogawa N, Hinoi E, Hiraiwa M, Kato S, Shinmura K, Annen R, Kobayashi M, Yamada Y, Nagatani S, Kurokawa Y, Tsuchiya H
Spine (Phila Pa 1976) 2024 Feb 15;49(4):285-293. Epub 2023 Oct 5 doi: 10.1097/BRS.0000000000004842. PMID: 37796156
Cerebrovascular Variants and the Role of the Selfish Brain in Young-Onset Hypertension.
Manghat NE, Robinson E, Mitrousi K, Rodrigues JCL, Hinton T, Paton JFR, Wise RG, Nightingale AK, Hart EC
Hypertension 2022 Jun;79(6):1265-1274. Epub 2022 Mar 16 doi: 10.1161/HYPERTENSIONAHA.121.18612. PMID: 35291807Free PMC Article
Infantile developmental thoracolumbar kyphosis with segmental subluxation of the spine: report of five patients and review of the literature.
Ganesan S, Karampalis C, Garrido E, Tsirikos AI
Bone Joint J 2015 Jul;97-B(7):982-7. doi: 10.1302/0301-620X.97B7.35665. PMID: 26130356
Variations in the intracranial vertebrobasilar system.
Songur A, Gonul Y, Ozen OA, Kucuker H, Uzun I, Bas O, Toktas M
Surg Radiol Anat 2008 May;30(3):257-64. Epub 2008 Feb 6 doi: 10.1007/s00276-008-0309-6. PMID: 18253692
Monochorionic monoamniotic twins: neonatal outcome.
Cordero L, Franco A, Joy SD
J Perinatol 2006 Mar;26(3):170-5. doi: 10.1038/sj.jp.7211457. PMID: 16467856

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