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Sclerosis of foot bone

MedGen UID:
866585
•Concept ID:
C4020931
•
Disease or Syndrome
Synonyms: Increased bone density in foot bone; Sclerosis of bones of the feet
 
HPO: HP:0100925

Definition

An elevation in bone density in one or more foot bones. Sclerosis is normally detected on a radiograph as an area of increased opacity. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSclerosis of foot bone

Professional guidelines

PubMed

Treatment of advanced stage osteochondrosis dissecans in the adolescent elbow using a hyaloronic acid-based scaffold: a case series of 5 patients.
Farr S, Pallamar M, Eder T, Ganger R
Arch Orthop Trauma Surg 2021 Sep;141(9):1541-1549. Epub 2021 Feb 4 doi: 10.1007/s00402-021-03773-8. PMID: 33543384Free PMC Article
A review of nonoperative treatment of Jones' fracture.
Zogby RG, Baker BE
Am J Sports Med 1987 Jul-Aug;15(4):304-7. doi: 10.1177/036354658701500402. PMID: 3661809
TREATMENT OF UNDISPLACED CARPAL NAVICULAR FRACTURES WHEN DIAGNOSIS HAS BEEN DELAYED.
PRATT GF
Wis Med J 1963 Dec;62:498-500. PMID: 14084939

Recent clinical studies

Etiology

Efficacy of intrathecal mesenchymal stem cell-neural progenitor therapy in progressive MS: results from a phase II, randomized, placebo-controlled clinical trial.
Harris VK, Stark J, Williams A, Roche M, Malin M, Kumar A, Carlson AL, Kizilbash C, Wollowitz J, Andy C, Gerber LM, Sadiq SA
Stem Cell Res Ther 2024 May 23;15(1):151. doi: 10.1186/s13287-024-03765-6. PMID: 38783390Free PMC Article
Interventions for promoting physical activity in people with neuromuscular disease.
Jones K, Hawke F, Newman J, Miller JA, Burns J, Jakovljevic DG, Gorman G, Turnbull DM, Ramdharry G
Cochrane Database Syst Rev 2021 May 24;5(5):CD013544. doi: 10.1002/14651858.CD013544.pub2. PMID: 34027632Free PMC Article
Sever's Disease (Calcaneal Apophysitis).
Ramponi DR, Baker C
Adv Emerg Nurs J 2019 Jan/Mar;41(1):10-14. doi: 10.1097/TME.0000000000000219. PMID: 30702528
Atlas of radiographic features of osteoarthritis of the ankle and hindfoot.
Kraus VB, Kilfoil TM, Hash TW 2nd, McDaniel G, Renner JB, Carrino JA, Adams S
Osteoarthritis Cartilage 2015 Dec;23(12):2059-2085. Epub 2015 Aug 28 doi: 10.1016/j.joca.2015.08.008. PMID: 26318654Free PMC Article
Charcot neuro-osteoarthropathy-current standards.
Petrova NL, Edmonds ME
Diabetes Metab Res Rev 2008 May-Jun;24 Suppl 1:S58-61. doi: 10.1002/dmrr.846. PMID: 18442182

Diagnosis

Sever's Disease (Calcaneal Apophysitis).
Ramponi DR, Baker C
Adv Emerg Nurs J 2019 Jan/Mar;41(1):10-14. doi: 10.1097/TME.0000000000000219. PMID: 30702528
Köhler Disease: Avascular Necrosis in the Child.
Chan JY, Young JL
Foot Ankle Clin 2019 Mar;24(1):83-88. Epub 2018 Dec 10 doi: 10.1016/j.fcl.2018.09.005. PMID: 30685015
Osteoid osteoma: multimodality imaging with focus on hybrid imaging.
Bhure U, Roos JE, Strobel K
Eur J Nucl Med Mol Imaging 2019 Apr;46(4):1019-1036. Epub 2018 Oct 19 doi: 10.1007/s00259-018-4181-2. PMID: 30341641
Charcot neuro-osteoarthropathy-current standards.
Petrova NL, Edmonds ME
Diabetes Metab Res Rev 2008 May-Jun;24 Suppl 1:S58-61. doi: 10.1002/dmrr.846. PMID: 18442182
Case report 443. Florid cortical and periosteal reactions due to stress fractures of the right femur and left calcaneus in a "break dancer".
Ihmeidan IH, Tehranzadeh J, Oldham SA, Mnaymneh W, Mnaymneh LG
Skeletal Radiol 1987;16(7):581-3. doi: 10.1007/BF00351276. PMID: 3423828

Therapy

Efficacy of intrathecal mesenchymal stem cell-neural progenitor therapy in progressive MS: results from a phase II, randomized, placebo-controlled clinical trial.
Harris VK, Stark J, Williams A, Roche M, Malin M, Kumar A, Carlson AL, Kizilbash C, Wollowitz J, Andy C, Gerber LM, Sadiq SA
Stem Cell Res Ther 2024 May 23;15(1):151. doi: 10.1186/s13287-024-03765-6. PMID: 38783390Free PMC Article
Midterm outcomes of midfoot and hindfoot arthrodesis with strut allograft for Müller-Weiss disease.
Lee TY, Wu CC, Yang KC, Yeh KT, Chen IH, Wang CC
BMC Musculoskelet Disord 2022 Jul 27;23(1):715. doi: 10.1186/s12891-022-05629-7. PMID: 35897013Free PMC Article
Interventions for promoting physical activity in people with neuromuscular disease.
Jones K, Hawke F, Newman J, Miller JA, Burns J, Jakovljevic DG, Gorman G, Turnbull DM, Ramdharry G
Cochrane Database Syst Rev 2021 May 24;5(5):CD013544. doi: 10.1002/14651858.CD013544.pub2. PMID: 34027632Free PMC Article
Revision of the aseptic and septic total ankle replacement.
Espinosa N, Wirth SH
Clin Podiatr Med Surg 2013 Apr;30(2):171-85. doi: 10.1016/j.cpm.2012.10.004. PMID: 23465807
Charcot neuro-osteoarthropathy-current standards.
Petrova NL, Edmonds ME
Diabetes Metab Res Rev 2008 May-Jun;24 Suppl 1:S58-61. doi: 10.1002/dmrr.846. PMID: 18442182

Prognosis

Skeletal Tuberculosis in Pediatric Population for 15 Years; Twenty Cases from Southern Turkey.
Çay Ü, Alabaz D, Gündeşlioglu ÖÖ, Mirioglu A, Pehlivan UA
Niger J Clin Pract 2023 Nov 1;26(11):1602-1609. Epub 2023 Dec 4 doi: 10.4103/njcp.njcp_699_22. PMID: 38044761
The frequency of Achilles and plantar calcaneal spurs in gout patients.
Duran E, Bilgin E, Ertenli Aİ, Kalyoncu U
Turk J Med Sci 2021 Aug 30;51(4):1841-1848. doi: 10.3906/sag-2011-201. PMID: 33754652Free PMC Article
Tuberculosis of the calcaneus in children.
Agarwal A, Kant KS, Suri T, Gupta N, Verma I, Shaharyar A
J Orthop Surg (Hong Kong) 2015 Apr;23(1):84-9. doi: 10.1177/230949901502300120. PMID: 25920652
Osteoid osteoma with an atypical nidus: A case report.
Jamshidi K, Shafipour R, Qomashi I
Foot Ankle Surg 2012 Mar;18(1):e9-11. doi: 10.1016/j.fas.2011.09.003. PMID: 22326016
Melorheostosis.
Taylor PM
J Foot Surg 1976 Summer;15(2):55-8. PMID: 1030721

Clinical prediction guides

Interventions for promoting physical activity in people with neuromuscular disease.
Jones K, Hawke F, Newman J, Miller JA, Burns J, Jakovljevic DG, Gorman G, Turnbull DM, Ramdharry G
Cochrane Database Syst Rev 2021 May 24;5(5):CD013544. doi: 10.1002/14651858.CD013544.pub2. PMID: 34027632Free PMC Article
The frequency of Achilles and plantar calcaneal spurs in gout patients.
Duran E, Bilgin E, Ertenli Aİ, Kalyoncu U
Turk J Med Sci 2021 Aug 30;51(4):1841-1848. doi: 10.3906/sag-2011-201. PMID: 33754652Free PMC Article
Atlas of radiographic features of osteoarthritis of the ankle and hindfoot.
Kraus VB, Kilfoil TM, Hash TW 2nd, McDaniel G, Renner JB, Carrino JA, Adams S
Osteoarthritis Cartilage 2015 Dec;23(12):2059-2085. Epub 2015 Aug 28 doi: 10.1016/j.joca.2015.08.008. PMID: 26318654Free PMC Article
Charcot neuro-osteoarthropathy-current standards.
Petrova NL, Edmonds ME
Diabetes Metab Res Rev 2008 May-Jun;24 Suppl 1:S58-61. doi: 10.1002/dmrr.846. PMID: 18442182
Hallux limitus and hallux rigidus. Clinical examination, radiographic findings, and natural history.
Camasta CA
Clin Podiatr Med Surg 1996 Jul;13(3):423-48. PMID: 8829034

Recent systematic reviews

Interventions for promoting physical activity in people with neuromuscular disease.
Jones K, Hawke F, Newman J, Miller JA, Burns J, Jakovljevic DG, Gorman G, Turnbull DM, Ramdharry G
Cochrane Database Syst Rev 2021 May 24;5(5):CD013544. doi: 10.1002/14651858.CD013544.pub2. PMID: 34027632Free PMC Article

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