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Adult Fibrolamellar Carcinoma

MedGen UID:
859696
Concept ID:
C3900102
Neoplastic Process

Definition

Fibrolamellar variant of hepatocellular carcinoma that occurs during adulthood. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAdult Fibrolamellar Carcinoma

Professional guidelines

PubMed

Aziz H, Brown ZJ, Panid Madani S, Kamel IR, Pawlik TM
J Am Coll Surg 2023 Feb 1;236(2):399-410. Epub 2022 Nov 4 doi: 10.1097/XCS.0000000000000476. PMID: 36648268
Chaudhari VA, Khobragade K, Bhandare M, Shrikhande SV
Chin Clin Oncol 2018 Oct;7(5):51. doi: 10.21037/cco.2018.08.08. PMID: 30395718
Wennerberg AE, Nalesnik MA, Coleman WB
Am J Pathol 1993 Oct;143(4):1050-4. PMID: 7692729Free PMC Article

Recent clinical studies

Etiology

Glavas D, Bao QR, Scarpa M, Ruffolo C, Brown ZJ, Pawlik TM, Spolverato G
J Gastrointest Surg 2023 Apr;27(4):705-715. Epub 2023 Feb 16 doi: 10.1007/s11605-023-05621-z. PMID: 36797535Free PMC Article
Ranganathan S, Lopez-Terrada D, Alaggio R
Pediatr Dev Pathol 2020 Mar-Apr;23(2):79-95. Epub 2019 Sep 25 doi: 10.1177/1093526619875228. PMID: 31554479
Sia D, Villanueva A, Friedman SL, Llovet JM
Gastroenterology 2017 Mar;152(4):745-761. Epub 2016 Dec 30 doi: 10.1053/j.gastro.2016.11.048. PMID: 28043904
Starzl TE, Iwatsuki S, Shaw BW Jr, Nalesnik MA, Farhi DC, Van Thiel DH
Surg Gynecol Obstet 1986 Feb;162(2):145-8. PMID: 3003942Free PMC Article
Friedman AC, Lichtenstein JE, Goodman Z, Fishman EK, Siegelman SS, Dachman AH
Radiology 1985 Dec;157(3):583-7. doi: 10.1148/radiology.157.3.2997835. PMID: 2997835

Diagnosis

Ranganathan S, Lopez-Terrada D, Alaggio R
Pediatr Dev Pathol 2020 Mar-Apr;23(2):79-95. Epub 2019 Sep 25 doi: 10.1177/1093526619875228. PMID: 31554479
Matsukuma KE, Yeh MM
Ann Diagn Pathol 2019 Feb;38:126-137. Epub 2018 Oct 12 doi: 10.1016/j.anndiagpath.2018.10.005. PMID: 30597357
Luther J, Dienstag JL
Clin Gastroenterol Hepatol 2019 Jan;17(1):A27. Epub 2018 Mar 2 doi: 10.1016/j.cgh.2018.02.040. PMID: 29505903
Koudah S, El Mouhadi S, Arrivé L
Clin Res Hepatol Gastroenterol 2012 Feb;36(1):5-6. Epub 2011 Nov 8 doi: 10.1016/j.clinre.2011.09.008. PMID: 22070972
Ruffin MT 4th
Am J Gastroenterol 1990 May;85(5):577-81. PMID: 2159697

Therapy

Dinh TA, Utria AF, Barry KC, Ma R, Abou-Alfa GK, Gordan JD, Jaffee EM, Scott JD, Zucman-Rossi J, O'Neill AF, Furth ME, Sethupathy P
Nat Rev Gastroenterol Hepatol 2022 May;19(5):328-342. Epub 2022 Feb 21 doi: 10.1038/s41575-022-00580-3. PMID: 35190728Free PMC Article
Shah PA, Cho J, Albitar HAH, Pajot G, Liu M, Ravi K
Am J Med 2020 Dec;133(12):e745-e746. Epub 2020 Jul 31 doi: 10.1016/j.amjmed.2020.06.022. PMID: 32739410
Lalazar G, Simon SM
Semin Liver Dis 2018 Feb;38(1):51-59. Epub 2018 Feb 22 doi: 10.1055/s-0037-1621710. PMID: 29471565Free PMC Article
Mafeld S, French J, Tiniakos D, Haugk B, Manas D, Littler P
Cardiovasc Intervent Radiol 2018 May;41(5):816-820. Epub 2018 Feb 21 doi: 10.1007/s00270-018-1903-6. PMID: 29468286Free PMC Article
Starzl TE, Iwatsuki S, Shaw BW Jr, Nalesnik MA, Farhi DC, Van Thiel DH
Surg Gynecol Obstet 1986 Feb;162(2):145-8. PMID: 3003942Free PMC Article

Prognosis

Ranganathan S, Lopez-Terrada D, Alaggio R
Pediatr Dev Pathol 2020 Mar-Apr;23(2):79-95. Epub 2019 Sep 25 doi: 10.1177/1093526619875228. PMID: 31554479
Sia D, Villanueva A, Friedman SL, Llovet JM
Gastroenterology 2017 Mar;152(4):745-761. Epub 2016 Dec 30 doi: 10.1053/j.gastro.2016.11.048. PMID: 28043904
Koudah S, El Mouhadi S, Arrivé L
Clin Res Hepatol Gastroenterol 2012 Feb;36(1):5-6. Epub 2011 Nov 8 doi: 10.1016/j.clinre.2011.09.008. PMID: 22070972
Ruffin MT 4th
Am J Gastroenterol 1990 May;85(5):577-81. PMID: 2159697
Nagorney DM, Adson MA, Weiland LH, Knight CD Jr, Smalley SR, Zinsmeister AR
Am J Surg 1985 Jan;149(1):113-9. doi: 10.1016/s0002-9610(85)80019-2. PMID: 2981486

Clinical prediction guides

Berkovitz A, Migler RD, Qureshi A, Rosemore C, Torbenson MS, Vaughan R, Marcotte E, Simon SM
Hepatol Commun 2022 Dec;6(12):3539-3549. Epub 2022 Oct 17 doi: 10.1002/hep4.2105. PMID: 36245434Free PMC Article
Schultz SP, Holtestaul T, Marenco CW, Bader JO, Horton JD, Nelson DW
J Surg Res 2022 Aug;276:261-271. Epub 2022 Apr 7 doi: 10.1016/j.jss.2022.03.006. PMID: 35398630
Ramai D, Ofosu A, Lai JK, Gao ZH, Adler DG
Dig Dis Sci 2021 Jan;66(1):308-314. Epub 2020 Feb 12 doi: 10.1007/s10620-020-06135-3. PMID: 32052215
Chaudhari VA, Khobragade K, Bhandare M, Shrikhande SV
Chin Clin Oncol 2018 Oct;7(5):51. doi: 10.21037/cco.2018.08.08. PMID: 30395718
Riehle KJ, Yeh MM, Yu JJ, Kenerson HL, Harris WP, Park JO, Yeung RS
Mod Pathol 2015 Jan;28(1):103-10. Epub 2014 Jun 13 doi: 10.1038/modpathol.2014.78. PMID: 24925055

Recent systematic reviews

Glavas D, Bao QR, Scarpa M, Ruffolo C, Brown ZJ, Pawlik TM, Spolverato G
J Gastrointest Surg 2023 Apr;27(4):705-715. Epub 2023 Feb 16 doi: 10.1007/s11605-023-05621-z. PMID: 36797535Free PMC Article
Aziz H, Brown ZJ, Panid Madani S, Kamel IR, Pawlik TM
J Am Coll Surg 2023 Feb 1;236(2):399-410. Epub 2022 Nov 4 doi: 10.1097/XCS.0000000000000476. PMID: 36648268

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