U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Recurrent Childhood Pilocytic Astrocytoma

MedGen UID:
857340
Concept ID:
C3897746
Neoplastic Process

Definition

The reemergence of pilocytic astrocytoma in childhood after a period of remission. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRecurrent Childhood Pilocytic Astrocytoma

Professional guidelines

PubMed

Malta TM, Sabedot TS, Morosini NS, Datta I, Garofano L, Vallentgoed W, Varn FS, Aldape K, D'Angelo F, Bakas S, Barnholtz-Sloan JS, Gan HK, Hasanain M, Hau AC, Johnson KC, Cazacu S, deCarvalho AC, Khasraw M, Kocakavuk E, Kouwenhoven MCM, Migliozzi S, Niclou SP, Niers JM, Ormond DR, Paek SH, Reifenberger G, Sillevis Smitt PA, Smits M, Stead LF, van den Bent MJ, Van Meir EG, Walenkamp A, Weiss T, Weller M, Westerman BA, Ylstra B, Wesseling P, Lasorella A, French PJ, Poisson LM; Consortium The GLASS, Verhaak RGW, Iavarone A, Noushmehr H
Cancer Res 2024 Mar 4;84(5):741-756. doi: 10.1158/0008-5472.CAN-23-2093. PMID: 38117484Free PMC Article
Silva AHD, Constantinides M, Valetopoulou A, Sgardelis P, Mankad K, D'Arco F, Jankovic I, Thompson D
Childs Nerv Syst 2022 Mar;38(3):577-586. Epub 2021 Dec 2 doi: 10.1007/s00381-021-05412-4. PMID: 34855000
Finlay JL, Wisoff JH
Childs Nerv Syst 1999 Nov;15(11-12):786-8. doi: 10.1007/s003810050471. PMID: 10603023

Recent clinical studies

Etiology

Chandler K, Pisharody VA, Grigorian J, Mao S, Ma T, Jahangiri A, Chern J, Hoang K
Neurosurg Focus 2024 Aug 1;57(2):E13. doi: 10.3171/2024.5.FOCUS2486. PMID: 39088855
Shoji T, Kanamori M, Saito R, Watanabe Y, Watanabe M, Fujimura M, Ogawa Y, Sonoda Y, Kumabe T, Kure S, Tominaga T
Neurol Med Chir (Tokyo) 2020 Jun 15;60(6):277-285. Epub 2020 May 14 doi: 10.2176/nmc.oa.2019-0208. PMID: 32404575Free PMC Article
Villanueva KG, Rea ND, Krieger MD
Pediatr Neurosurg 2019;54(6):375-385. Epub 2019 Oct 8 doi: 10.1159/000503110. PMID: 31593969
Fangusaro J, Onar-Thomas A, Young Poussaint T, Wu S, Ligon AH, Lindeman N, Banerjee A, Packer RJ, Kilburn LB, Goldman S, Pollack IF, Qaddoumi I, Jakacki RI, Fisher PG, Dhall G, Baxter P, Kreissman SG, Stewart CF, Jones DTW, Pfister SM, Vezina G, Stern JS, Panigrahy A, Patay Z, Tamrazi B, Jones JY, Haque SS, Enterline DS, Cha S, Fisher MJ, Doyle LA, Smith M, Dunkel IJ, Fouladi M
Lancet Oncol 2019 Jul;20(7):1011-1022. Epub 2019 May 28 doi: 10.1016/S1470-2045(19)30277-3. PMID: 31151904Free PMC Article
Finlay JL, Wisoff JH
Childs Nerv Syst 1999 Nov;15(11-12):786-8. doi: 10.1007/s003810050471. PMID: 10603023

Diagnosis

Dias SF, Richards O, Elliot M, Chumas P
Adv Tech Stand Neurosurg 2024;50:147-183. doi: 10.1007/978-3-031-53578-9_5. PMID: 38592530
Brunhara BB, Becker AP, Neder L, Gonçalves PG, de Oliveira C, Clara CA, Reis RM, Bidinotto LT
Neuropathology 2021 Feb;41(1):21-28. Epub 2020 Nov 15 doi: 10.1111/neup.12698. PMID: 33191640
Cortez GM, Monteiro A, Ludwig B, Hanel R
BMJ Case Rep 2020 Oct 29;13(10) doi: 10.1136/bcr-2020-235662. PMID: 33122224Free PMC Article
Fangusaro J, Onar-Thomas A, Young Poussaint T, Wu S, Ligon AH, Lindeman N, Banerjee A, Packer RJ, Kilburn LB, Goldman S, Pollack IF, Qaddoumi I, Jakacki RI, Fisher PG, Dhall G, Baxter P, Kreissman SG, Stewart CF, Jones DTW, Pfister SM, Vezina G, Stern JS, Panigrahy A, Patay Z, Tamrazi B, Jones JY, Haque SS, Enterline DS, Cha S, Fisher MJ, Doyle LA, Smith M, Dunkel IJ, Fouladi M
Lancet Oncol 2019 Jul;20(7):1011-1022. Epub 2019 May 28 doi: 10.1016/S1470-2045(19)30277-3. PMID: 31151904Free PMC Article
Brown CE, Badie B, Barish ME, Weng L, Ostberg JR, Chang WC, Naranjo A, Starr R, Wagner J, Wright C, Zhai Y, Bading JR, Ressler JA, Portnow J, D'Apuzzo M, Forman SJ, Jensen MC
Clin Cancer Res 2015 Sep 15;21(18):4062-72. Epub 2015 Jun 9 doi: 10.1158/1078-0432.CCR-15-0428. PMID: 26059190Free PMC Article

Therapy

Brown CE, Rodriguez A, Palmer J, Ostberg JR, Naranjo A, Wagner JR, Aguilar B, Starr R, Weng L, Synold TW, Tran V, Wang S, Reik A, D'Apuzzo M, Ressler JA, Zhou Y, Mendel M, Gregory PD, Holmes MC, Tang WW, Forman SJ, Jensen MC, Badie B
Neuro Oncol 2022 Aug 1;24(8):1318-1330. doi: 10.1093/neuonc/noac024. PMID: 35100373Free PMC Article
Vitanza NA, Johnson AJ, Wilson AL, Brown C, Yokoyama JK, Künkele A, Chang CA, Rawlings-Rhea S, Huang W, Seidel K, Albert CM, Pinto N, Gust J, Finn LS, Ojemann JG, Wright J, Orentas RJ, Baldwin M, Gardner RA, Jensen MC, Park JR
Nat Med 2021 Sep;27(9):1544-1552. Epub 2021 Jul 12 doi: 10.1038/s41591-021-01404-8. PMID: 34253928
Fangusaro J, Onar-Thomas A, Young Poussaint T, Wu S, Ligon AH, Lindeman N, Banerjee A, Packer RJ, Kilburn LB, Goldman S, Pollack IF, Qaddoumi I, Jakacki RI, Fisher PG, Dhall G, Baxter P, Kreissman SG, Stewart CF, Jones DTW, Pfister SM, Vezina G, Stern JS, Panigrahy A, Patay Z, Tamrazi B, Jones JY, Haque SS, Enterline DS, Cha S, Fisher MJ, Doyle LA, Smith M, Dunkel IJ, Fouladi M
Lancet Oncol 2019 Jul;20(7):1011-1022. Epub 2019 May 28 doi: 10.1016/S1470-2045(19)30277-3. PMID: 31151904Free PMC Article
Brown CE, Alizadeh D, Starr R, Weng L, Wagner JR, Naranjo A, Ostberg JR, Blanchard MS, Kilpatrick J, Simpson J, Kurien A, Priceman SJ, Wang X, Harshbarger TL, D'Apuzzo M, Ressler JA, Jensen MC, Barish ME, Chen M, Portnow J, Forman SJ, Badie B
N Engl J Med 2016 Dec 29;375(26):2561-9. doi: 10.1056/NEJMoa1610497. PMID: 28029927Free PMC Article
Brown CE, Badie B, Barish ME, Weng L, Ostberg JR, Chang WC, Naranjo A, Starr R, Wagner J, Wright C, Zhai Y, Bading JR, Ressler JA, Portnow J, D'Apuzzo M, Forman SJ, Jensen MC
Clin Cancer Res 2015 Sep 15;21(18):4062-72. Epub 2015 Jun 9 doi: 10.1158/1078-0432.CCR-15-0428. PMID: 26059190Free PMC Article

Prognosis

Chandler K, Pisharody VA, Grigorian J, Mao S, Ma T, Jahangiri A, Chern J, Hoang K
Neurosurg Focus 2024 Aug 1;57(2):E13. doi: 10.3171/2024.5.FOCUS2486. PMID: 39088855
Lucas CG, Sloan EA, Gupta R, Wu J, Pratt D, Vasudevan HN, Ravindranathan A, Barreto J, Williams EA, Shai A, Whipple NS, Bruggers CS, Maher O, Nabors B, Rodriguez M, Samuel D, Brown M, Carmichael J, Lu R, Mirchia K, Sullivan DV, Pekmezci M, Tihan T, Bollen AW, Perry A, Banerjee A, Mueller S, Gupta N, Hervey-Jumper SL, Oberheim Bush NA, Daras M, Taylor JW, Butowski NA, de Groot J, Clarke JL, Raleigh DR, Costello JF, Phillips JJ, Reddy AT, Chang SM, Berger MS, Solomon DA
Acta Neuropathol 2022 Oct;144(4):747-765. Epub 2022 Aug 9 doi: 10.1007/s00401-022-02478-5. PMID: 35945463Free PMC Article
Brunhara BB, Becker AP, Neder L, Gonçalves PG, de Oliveira C, Clara CA, Reis RM, Bidinotto LT
Neuropathology 2021 Feb;41(1):21-28. Epub 2020 Nov 15 doi: 10.1111/neup.12698. PMID: 33191640
Fangusaro J, Onar-Thomas A, Young Poussaint T, Wu S, Ligon AH, Lindeman N, Banerjee A, Packer RJ, Kilburn LB, Goldman S, Pollack IF, Qaddoumi I, Jakacki RI, Fisher PG, Dhall G, Baxter P, Kreissman SG, Stewart CF, Jones DTW, Pfister SM, Vezina G, Stern JS, Panigrahy A, Patay Z, Tamrazi B, Jones JY, Haque SS, Enterline DS, Cha S, Fisher MJ, Doyle LA, Smith M, Dunkel IJ, Fouladi M
Lancet Oncol 2019 Jul;20(7):1011-1022. Epub 2019 May 28 doi: 10.1016/S1470-2045(19)30277-3. PMID: 31151904Free PMC Article
Finlay JL, Wisoff JH
Childs Nerv Syst 1999 Nov;15(11-12):786-8. doi: 10.1007/s003810050471. PMID: 10603023

Clinical prediction guides

Fangusaro J, Onar-Thomas A, Young Poussaint T, Wu S, Ligon AH, Lindeman N, Banerjee A, Packer RJ, Kilburn LB, Goldman S, Pollack IF, Qaddoumi I, Jakacki RI, Fisher PG, Dhall G, Baxter P, Kreissman SG, Stewart CF, Jones DTW, Pfister SM, Vezina G, Stern JS, Panigrahy A, Patay Z, Tamrazi B, Jones JY, Haque SS, Enterline DS, Cha S, Fisher MJ, Doyle LA, Smith M, Dunkel IJ, Fouladi M
Lancet Oncol 2019 Jul;20(7):1011-1022. Epub 2019 May 28 doi: 10.1016/S1470-2045(19)30277-3. PMID: 31151904Free PMC Article
Brown CE, Alizadeh D, Starr R, Weng L, Wagner JR, Naranjo A, Ostberg JR, Blanchard MS, Kilpatrick J, Simpson J, Kurien A, Priceman SJ, Wang X, Harshbarger TL, D'Apuzzo M, Ressler JA, Jensen MC, Barish ME, Chen M, Portnow J, Forman SJ, Badie B
N Engl J Med 2016 Dec 29;375(26):2561-9. doi: 10.1056/NEJMoa1610497. PMID: 28029927Free PMC Article
Brown CE, Badie B, Barish ME, Weng L, Ostberg JR, Chang WC, Naranjo A, Starr R, Wagner J, Wright C, Zhai Y, Bading JR, Ressler JA, Portnow J, D'Apuzzo M, Forman SJ, Jensen MC
Clin Cancer Res 2015 Sep 15;21(18):4062-72. Epub 2015 Jun 9 doi: 10.1158/1078-0432.CCR-15-0428. PMID: 26059190Free PMC Article
Jones DT, Hutter B, Jäger N, Korshunov A, Kool M, Warnatz HJ, Zichner T, Lambert SR, Ryzhova M, Quang DA, Fontebasso AM, Stütz AM, Hutter S, Zuckermann M, Sturm D, Gronych J, Lasitschka B, Schmidt S, Seker-Cin H, Witt H, Sultan M, Ralser M, Northcott PA, Hovestadt V, Bender S, Pfaff E, Stark S, Faury D, Schwartzentruber J, Majewski J, Weber UD, Zapatka M, Raeder B, Schlesner M, Worth CL, Bartholomae CC, von Kalle C, Imbusch CD, Radomski S, Lawerenz C, van Sluis P, Koster J, Volckmann R, Versteeg R, Lehrach H, Monoranu C, Winkler B, Unterberg A, Herold-Mende C, Milde T, Kulozik AE, Ebinger M, Schuhmann MU, Cho YJ, Pomeroy SL, von Deimling A, Witt O, Taylor MD, Wolf S, Karajannis MA, Eberhart CG, Scheurlen W, Hasselblatt M, Ligon KL, Kieran MW, Korbel JO, Yaspo ML, Brors B, Felsberg J, Reifenberger G, Collins VP, Jabado N, Eils R, Lichter P, Pfister SM; International Cancer Genome Consortium PedBrain Tumor Project
Nat Genet 2013 Aug;45(8):927-32. Epub 2013 Jun 30 doi: 10.1038/ng.2682. PMID: 23817572Free PMC Article
Finlay JL, Wisoff JH
Childs Nerv Syst 1999 Nov;15(11-12):786-8. doi: 10.1007/s003810050471. PMID: 10603023

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...