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Remote Placental Infarction

MedGen UID:
857315
•Concept ID:
C3897721
•
Disease or Syndrome
Synonym: Remote Placental Infarct

Definition

A focus of necrotic placental parenchyma with marked hyalinization and fibrosis with complete absence of the necrotic chorionic villi, which is frequently more than 7 days of duration. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRemote Placental Infarction

Recent clinical studies

Etiology

Placental recent/on-going foetal vascular malperfusion with endothelial fragmentation is diagnostically equivalent to established distal villous lesions of foetal vascular malperfusion.
Stanek J
Pol J Pathol 2022;73(3):198-207. doi: 10.5114/pjp.2022.124487. PMID: 36734434

Diagnosis

Placental recent/on-going foetal vascular malperfusion with endothelial fragmentation is diagnostically equivalent to established distal villous lesions of foetal vascular malperfusion.
Stanek J
Pol J Pathol 2022;73(3):198-207. doi: 10.5114/pjp.2022.124487. PMID: 36734434
Lethal hypoplasia and developmental anomalies of the lungs in a newborn with intrauterine adrenal hemorrhage and cerebral infarcts: a proposed pulmonary disruption sequence.
Lertsburapa T, Vargas D, Lambert-Messerlian G, Tantravahi U, Gündoğan F, DeLaMonte S, Coyle MG, De Paepe ME
Pediatr Dev Pathol 2014 Sep-Oct;17(5):374-81. Epub 2014 Jun 27 doi: 10.2350/14-05-1485-CR.1. PMID: 24971487
Successful pregnancy in a patient with portal hypertension secondary to portal vein thrombosis due to essential thrombocythaemia: a rare case.
Buyukbayrak EE, Ergen B, Karageyim Karsidag AY, Kars B, Turan C, Birtas Atesoglu E
J Matern Fetal Neonatal Med 2010 Feb;23(2):187-9. doi: 10.3109/14767050903067329. PMID: 20074024

Therapy

Epicardial placement of human placental membrane protects from heart injury in a swine model of myocardial infarction.
Skaria RS, Lopez-Pier MA, Kathuria BS, Leber CJ, Langlais PR, Aras SG, Khalpey ZI, Hitscherich PG, Chnari E, Long M, Churko JM, Runyan RB, Konhilas JP
Physiol Rep 2023 Oct;11(20):e15838. doi: 10.14814/phy2.15838. PMID: 37849042Free PMC Article

Prognosis

Placental recent/on-going foetal vascular malperfusion with endothelial fragmentation is diagnostically equivalent to established distal villous lesions of foetal vascular malperfusion.
Stanek J
Pol J Pathol 2022;73(3):198-207. doi: 10.5114/pjp.2022.124487. PMID: 36734434

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