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Memory dysfunction

MedGen UID:: 854406
•Concept ID:: C3887551
•: Mental or Behavioral Dysfunction

Synonym:	Memory Dysfunction
SNOMED CT:	Memory dysfunction (386807006)

Definition

Interference or disruption of memory processes. Memory dysfunction refers to the inability to store and retrieve information. This term encompasses a large number of problems and issues associated with intellectual functioning. 2005 [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVMemory dysfunction

Pathological Conditions, Signs and Symptoms
- Pathological process
  - Disease
    - Mental disorder
      - Memory dysfunction
        Memory impairment
        Long term memory impairment
        Anterograde amnesia
        Retrograde amnesia
        Progressive forgetfulness
        Short term memory impairment
        Deficit in phonologic short-term memory
        Transient global amnesia

Professional guidelines

PubMed

Pathophysiology and Treatment of Memory Dysfunction After Traumatic Brain Injury.

Paterno R, Folweiler KA, Cohen AS
Curr Neurol Neurosci Rep 2017 Jul;17(7):52. doi: 10.1007/s11910-017-0762-x. PMID: 28500417 Free PMC Article

Erythropoietin: a candidate treatment for mood symptoms and memory dysfunction in depression.

Miskowiak KW, Vinberg M, Harmer CJ, Ehrenreich H, Kessing LV
Psychopharmacology (Berl) 2012 Feb;219(3):687-98. Epub 2011 Sep 23 doi: 10.1007/s00213-011-2511-1. PMID: 21947319

Treatment strategies of age-related memory dysfunction by modulation of neuronal plasticity.

Blank T, Nijholt I, Spiess J
Mini Rev Med Chem 2007 Jan;7(1):55-64. doi: 10.2174/138955707779317803. PMID: 17266638

See all (36)

Recent clinical studies

Etiology

Sleep disturbance and memory dysfunction in early multiple sclerosis.

Sumowski JF, Horng S, Brandstadter R, Krieger S, Leavitt VM, Katz Sand I, Fabian M, Klineova S, Graney R, Riley CS, Lublin FD, Miller AE, Varga AW
Ann Clin Transl Neurol 2021 Jun;8(6):1172-1182. Epub 2021 May 5 doi: 10.1002/acn3.51262. PMID: 33951348 Free PMC Article

Post-Stroke Working Memory Dysfunction: A Meta-Analysis and Systematic Review.

Lugtmeijer S, Lammers NA, de Haan EHF, de Leeuw FE, Kessels RPC
Neuropsychol Rev 2021 Mar;31(1):202-219. Epub 2020 Nov 24 doi: 10.1007/s11065-020-09462-4. PMID: 33230717 Free PMC Article

Memory Impairments and Psychosis Prediction: A Scoping Review and Theoretical Overview.

Seabury RD, Cannon TD
Neuropsychol Rev 2020 Dec;30(4):521-545. Epub 2020 Nov 23 doi: 10.1007/s11065-020-09464-2. PMID: 33226539

Neural oscillations and brain stimulation in Alzheimer's disease.

Jafari Z, Kolb BE, Mohajerani MH
Prog Neurobiol 2020 Nov;194:101878. Epub 2020 Jun 29 doi: 10.1016/j.pneurobio.2020.101878. PMID: 32615147

The psychosis spectrum in Parkinson disease.

Ffytche DH, Creese B, Politis M, Chaudhuri KR, Weintraub D, Ballard C, Aarsland D
Nat Rev Neurol 2017 Feb;13(2):81-95. Epub 2017 Jan 20 doi: 10.1038/nrneurol.2016.200. PMID: 28106066 Free PMC Article

See all (482)

Diagnosis

Memory Dysfunction.

Fernandez-Romero R, Spica DM
Continuum (Minneap Minn) 2021 Dec 1;27(6):1562-1585. doi: 10.1212/CON.0000000000001020. PMID: 34881726

Neural oscillations and brain stimulation in Alzheimer's disease.

Jafari Z, Kolb BE, Mohajerani MH
Prog Neurobiol 2020 Nov;194:101878. Epub 2020 Jun 29 doi: 10.1016/j.pneurobio.2020.101878. PMID: 32615147

Memory Dysfunction.

Gliebus GP
Continuum (Minneap Minn) 2018 Jun;24(3, BEHAVIORAL NEUROLOGY AND PSYCHIATRY):727-744. doi: 10.1212/CON.0000000000000619. PMID: 29851875

Memory dysfunction.

Matthews BR
Continuum (Minneap Minn) 2015 Jun;21(3 Behavioral Neurology and Neuropsychiatry):613-26. doi: 10.1212/01.CON.0000466656.59413.29. PMID: 26039844 Free PMC Article

Sleep and epilepsy.

Bazil CW
Semin Neurol 2002 Sep;22(3):321-7. doi: 10.1055/s-2002-36651. PMID: 12528057

See all (366)

Therapy

Potential mechanisms of metformin-induced memory impairment.

Alhowail A
Eur Rev Med Pharmacol Sci 2021 Jul;25(14):4757-4761. doi: 10.26355/eurrev_202107_26387. PMID: 34337723

Baicalin mitigates cognitive impairment and protects neurons from microglia-mediated neuroinflammation via suppressing NLRP3 inflammasomes and TLR4/NF-κB signaling pathway.

Jin X, Liu MY, Zhang DF, Zhong X, Du K, Qian P, Yao WF, Gao H, Wei MJ
CNS Neurosci Ther 2019 May;25(5):575-590. Epub 2019 Jan 24 doi: 10.1111/cns.13086. PMID: 30676698 Free PMC Article

Transcranial magnetic stimulation of the precuneus enhances memory and neural activity in prodromal Alzheimer's disease.

Koch G, Bonnì S, Pellicciari MC, Casula EP, Mancini M, Esposito R, Ponzo V, Picazio S, Di Lorenzo F, Serra L, Motta C, Maiella M, Marra C, Cercignani M, Martorana A, Caltagirone C, Bozzali M
Neuroimage 2018 Apr 1;169:302-311. Epub 2017 Dec 19 doi: 10.1016/j.neuroimage.2017.12.048. PMID: 29277405

Phosphodiesterase inhibition in cognitive decline.

García-Barroso C, Ugarte A, Martínez M, Rico AJ, Lanciego JL, Franco R, Oyarzabal J, Cuadrado-Tejedor M, García-Osta A
J Alzheimers Dis 2014;42 Suppl 4:S561-73. doi: 10.3233/JAD-141341. PMID: 25125473

Sleep and epilepsy.

Bazil CW
Semin Neurol 2002 Sep;22(3):321-7. doi: 10.1055/s-2002-36651. PMID: 12528057

See all (230)

Prognosis

A Recent Update on Pathophysiology and Therapeutic Interventions of Alzheimer's Disease.

Kashif M, Sivaprakasam P, Vijendra P, Waseem M, Pandurangan AK
Curr Pharm Des 2023;29(43):3428-3441. doi: 10.2174/0113816128264355231121064704. PMID: 38038007

Memory Impairments and Psychosis Prediction: A Scoping Review and Theoretical Overview.

Seabury RD, Cannon TD
Neuropsychol Rev 2020 Dec;30(4):521-545. Epub 2020 Nov 23 doi: 10.1007/s11065-020-09464-2. PMID: 33226539

Neural oscillations and brain stimulation in Alzheimer's disease.

Jafari Z, Kolb BE, Mohajerani MH
Prog Neurobiol 2020 Nov;194:101878. Epub 2020 Jun 29 doi: 10.1016/j.pneurobio.2020.101878. PMID: 32615147

Memory impairment and awareness of memory deficits in early-stage Alzheimer's disease.

Mimura M
Tohoku J Exp Med 2008 Jun;215(2):133-40. doi: 10.1620/tjem.215.133. PMID: 18577842

Pharmacology of antidepressants.

Richelson E
Psychopathology 1987;20 Suppl 1:1-12. doi: 10.1159/000284517. PMID: 2892225

See all (231)

Clinical prediction guides

Memory Impairments and Psychosis Prediction: A Scoping Review and Theoretical Overview.

Seabury RD, Cannon TD
Neuropsychol Rev 2020 Dec;30(4):521-545. Epub 2020 Nov 23 doi: 10.1007/s11065-020-09464-2. PMID: 33226539

Neural oscillations and brain stimulation in Alzheimer's disease.

Jafari Z, Kolb BE, Mohajerani MH
Prog Neurobiol 2020 Nov;194:101878. Epub 2020 Jun 29 doi: 10.1016/j.pneurobio.2020.101878. PMID: 32615147

Development of the clinical assessment scale in autoimmune encephalitis.

Lim JA, Lee ST, Moon J, Jun JS, Kim TJ, Shin YW, Abdullah S, Byun JI, Sunwoo JS, Kim KT, Yang TW, Lee WJ, Moon HJ, Kim DW, Lim BC, Cho YW, Yang TH, Kim HJ, Kim YS, Koo YS, Park B, Jung KH, Kim M, Park KI, Jung KY, Chu K, Lee SK
Ann Neurol 2019 Mar;85(3):352-358. Epub 2019 Feb 10 doi: 10.1002/ana.25421. PMID: 30675918

Transcranial magnetic stimulation of the precuneus enhances memory and neural activity in prodromal Alzheimer's disease.

The behavioural/dysexecutive variant of Alzheimer's disease: clinical, neuroimaging and pathological features.

Ossenkoppele R, Pijnenburg YA, Perry DC, Cohn-Sheehy BI, Scheltens NM, Vogel JW, Kramer JH, van der Vlies AE, La Joie R, Rosen HJ, van der Flier WM, Grinberg LT, Rozemuller AJ, Huang EJ, van Berckel BN, Miller BL, Barkhof F, Jagust WJ, Scheltens P, Seeley WW, Rabinovici GD
Brain 2015 Sep;138(Pt 9):2732-49. Epub 2015 Jul 2 doi: 10.1093/brain/awv191. PMID: 26141491 Free PMC Article

See all (424)

Recent systematic reviews

Transcranial magnetic stimulation neurophysiology in patients with non-Alzheimer's neurodegenerative diseases: A systematic review and meta-analysis.

Mimura Y, Tobari Y, Nakahara K, Nakajima S, Yoshida K, Mimura M, Noda Y
Neurosci Biobehav Rev 2023 Dec;155:105451. Epub 2023 Nov 4 doi: 10.1016/j.neubiorev.2023.105451. PMID: 37926239

An investigation of working memory deficits in depression using the n-back task: A systematic review and meta-analysis.

Nikolin S, Tan YY, Schwaab A, Moffa A, Loo CK, Martin D
J Affect Disord 2021 Apr 1;284:1-8. Epub 2021 Feb 5 doi: 10.1016/j.jad.2021.01.084. PMID: 33581489

Mechanisms of cognitive impairment in temporal lobe epilepsy: A systematic review of resting-state functional connectivity studies.

Ives-Deliperi V, Butler JT
Epilepsy Behav 2021 Feb;115:107686. Epub 2020 Dec 24 doi: 10.1016/j.yebeh.2020.107686. PMID: 33360743

Post-Stroke Working Memory Dysfunction: A Meta-Analysis and Systematic Review.

Lugtmeijer S, Lammers NA, de Haan EHF, de Leeuw FE, Kessels RPC
Neuropsychol Rev 2021 Mar;31(1):202-219. Epub 2020 Nov 24 doi: 10.1007/s11065-020-09462-4. PMID: 33230717 Free PMC Article

Poststroke memory function in nondemented patients: a systematic review on frequency and neuroimaging correlates.

Snaphaan L, de Leeuw FE
Stroke 2007 Jan;38(1):198-203. Epub 2006 Dec 7 doi: 10.1161/01.STR.0000251842.34322.8f. PMID: 17158333

See all (12)

MedGen

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Memory dysfunction

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Practice guidelines

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