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Bartholin gland carcinoma

MedGen UID:
83888
•Concept ID:
C0349561
•
Neoplastic Process
Synonyms: Bartholin gland cancer; Bartholin Gland Carcinoma; bartholin gland carcinoma; Bartholin gland carcinoma (disease); Bartholin's Gland Cancer; Bartholin's gland cancer; Bartholin's Gland Carcinoma; Bartholin's gland carcinoma; Carcinoma of Bartholin gland; Carcinoma of Bartholin's gland; Carcinoma of Bartholin's Gland; carcinoma of Bartholin's gland; carcinoma of major vestibular gland; Carcinoma of the Bartholin's Gland; carcinoma of the Bartholin's gland; major vestibular gland carcinoma
SNOMED CT: Bartholin's gland carcinoma (399533005); Bartholin gland carcinoma (399533005); Carcinoma of Bartholin gland (276876007); Carcinoma of Bartholin's gland (276876007)
 
HPO: HP:0030419
Monarch Initiative: MONDO:0002829

Definition

A cancer arising in a cell of the Bartholin gland, a racemose gland located slightly posterior to the opening of the vagina. [from HPO]

Professional guidelines

PubMed

Case series on the management and outcomes of Bartholin gland carcinoma.
Abdul-Aziz S, Jayraj AS, Adusumalli M, Rajan Babu A
Eur J Obstet Gynecol Reprod Biol 2024 Aug;299:26-31. Epub 2024 May 23 doi: 10.1016/j.ejogrb.2024.05.028. PMID: 38824810
Management of primary and recurrent Bartholin's gland carcinoma: A systematic review on behalf of MITO Rare Cancer Group.
Turetta C, Mazzeo R, Capalbo G, Miano S, Fruscio R, Di Donato V, Falcone F, Mangili G, Pignata S, Palaia I
Tumori 2024 Apr;110(2):96-108. Epub 2023 Nov 13 doi: 10.1177/03008916231208308. PMID: 37953636
Postmenopausal bartholin gland enlargement: a hospital-based cancer risk assessment.
Visco AG, Del Priore G
Obstet Gynecol 1996 Feb;87(2):286-90. doi: 10.1016/0029-7844(95)00404-1. PMID: 8559540

Recent clinical studies

Etiology

Case series on the management and outcomes of Bartholin gland carcinoma.
Abdul-Aziz S, Jayraj AS, Adusumalli M, Rajan Babu A
Eur J Obstet Gynecol Reprod Biol 2024 Aug;299:26-31. Epub 2024 May 23 doi: 10.1016/j.ejogrb.2024.05.028. PMID: 38824810
Management of primary and recurrent Bartholin's gland carcinoma: A systematic review on behalf of MITO Rare Cancer Group.
Turetta C, Mazzeo R, Capalbo G, Miano S, Fruscio R, Di Donato V, Falcone F, Mangili G, Pignata S, Palaia I
Tumori 2024 Apr;110(2):96-108. Epub 2023 Nov 13 doi: 10.1177/03008916231208308. PMID: 37953636
Bartholin Gland Carcinoma: Clinicopathologic Features, Including p16 Expression and Clinical Outcome.
Nazeran T, Cheng AS, Karnezis AN, Tinker AV, Gilks CB
Int J Gynecol Pathol 2019 Mar;38(2):189-195. doi: 10.1097/PGP.0000000000000489. PMID: 29406447
Carcinoma of the Bartholin Gland: A Review of 33 Cases.
Bhalwal AB, Nick AM, Dos Reis R, Chen CL, Munsell MF, Ramalingam P, Salcedo MP, Ramirez PT, Sood AK, Schmeler KM
Int J Gynecol Cancer 2016 May;26(4):785-9. doi: 10.1097/IGC.0000000000000656. PMID: 26844611Free PMC Article
Primary Bartholin gland carcinoma: a report of seven cases.
Obermair A, Koller S, Crandon AJ, Perrin L, Nicklin JL
Aust N Z J Obstet Gynaecol 2001 Feb;41(1):78-81. doi: 10.1111/j.1479-828x.2001.tb01299.x. PMID: 11284653

Diagnosis

Case series on the management and outcomes of Bartholin gland carcinoma.
Abdul-Aziz S, Jayraj AS, Adusumalli M, Rajan Babu A
Eur J Obstet Gynecol Reprod Biol 2024 Aug;299:26-31. Epub 2024 May 23 doi: 10.1016/j.ejogrb.2024.05.028. PMID: 38824810
Pitfalls in Pathology-Nodular Hyperplasia of Bartholin's Gland.
Bilek M, Barrett T, Casey S, Heller DS
Int J Surg Pathol 2022 Apr;30(2):167-169. Epub 2021 Jun 18 doi: 10.1177/10668969211027268. PMID: 34142902
Difficulties of clinical and histopathological diagnosis in advanced vulvar clear cell carcinoma.
Herghelegiu CG, Neacşu A, Oprescu ND, Cărbunaru AE, Brăila AD, Curea FG, Marcu ML, Ioan RG, Bohîlţea RE
Rom J Morphol Embryol 2018;59(4):1233-1237. PMID: 30845306
Carcinoma of the Bartholin Gland: A Review of 33 Cases.
Bhalwal AB, Nick AM, Dos Reis R, Chen CL, Munsell MF, Ramalingam P, Salcedo MP, Ramirez PT, Sood AK, Schmeler KM
Int J Gynecol Cancer 2016 May;26(4):785-9. doi: 10.1097/IGC.0000000000000656. PMID: 26844611Free PMC Article
Bartholin gland carcinoma.
Copeland LJ, Sneige N, Gershenson DM, McGuffee VB, Abdul-Karim F, Rutledge FN
Obstet Gynecol 1986 Jun;67(6):794-801. doi: 10.1097/00006250-198606000-00009. PMID: 3010205

Therapy

Carcinoma of the Bartholin Gland: A Review of 33 Cases.
Bhalwal AB, Nick AM, Dos Reis R, Chen CL, Munsell MF, Ramalingam P, Salcedo MP, Ramirez PT, Sood AK, Schmeler KM
Int J Gynecol Cancer 2016 May;26(4):785-9. doi: 10.1097/IGC.0000000000000656. PMID: 26844611Free PMC Article
Heparin-associated thrombocytopenia: a complication of low-dose heparin prophylaxis.
Cottingham JK, Wheelock JB
Mil Med 1989 May;154(5):242-4. PMID: 2499837

Prognosis

Brain Metastasis From Bartholin Gland Carcinoma.
Jamshidi AM, Eichberg DG, Gultekin S, Komotar RJ
World Neurosurg 2020 Nov;143:280-284. Epub 2020 Jul 28 doi: 10.1016/j.wneu.2020.07.122. PMID: 32736128
Difficulties of clinical and histopathological diagnosis in advanced vulvar clear cell carcinoma.
Herghelegiu CG, Neacşu A, Oprescu ND, Cărbunaru AE, Brăila AD, Curea FG, Marcu ML, Ioan RG, Bohîlţea RE
Rom J Morphol Embryol 2018;59(4):1233-1237. PMID: 30845306
Bartholin gland cancer.
Di Donato V, Casorelli A, Bardhi E, Vena F, Marchetti C, Muzii L, Benedetti Panici P
Crit Rev Oncol Hematol 2017 Sep;117:1-11. Epub 2017 Jun 13 doi: 10.1016/j.critrevonc.2017.06.005. PMID: 28807231
Carcinoma of the Bartholin Gland: A Review of 33 Cases.
Bhalwal AB, Nick AM, Dos Reis R, Chen CL, Munsell MF, Ramalingam P, Salcedo MP, Ramirez PT, Sood AK, Schmeler KM
Int J Gynecol Cancer 2016 May;26(4):785-9. doi: 10.1097/IGC.0000000000000656. PMID: 26844611Free PMC Article
Primary carcinoma of the Bartholin gland: a report of 14 cases and review of the literature.
Leuchter RS, Hacker NF, Voet RL, Berek JS, Townsend DE, Lagasse LD
Obstet Gynecol 1982 Sep;60(3):361-8. PMID: 7121917

Clinical prediction guides

Bartholin Gland Carcinoma: Clinicopathologic Features, Including p16 Expression and Clinical Outcome.
Nazeran T, Cheng AS, Karnezis AN, Tinker AV, Gilks CB
Int J Gynecol Pathol 2019 Mar;38(2):189-195. doi: 10.1097/PGP.0000000000000489. PMID: 29406447

Recent systematic reviews

Management of primary and recurrent Bartholin's gland carcinoma: A systematic review on behalf of MITO Rare Cancer Group.
Turetta C, Mazzeo R, Capalbo G, Miano S, Fruscio R, Di Donato V, Falcone F, Mangili G, Pignata S, Palaia I
Tumori 2024 Apr;110(2):96-108. Epub 2023 Nov 13 doi: 10.1177/03008916231208308. PMID: 37953636

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