U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Benign neoplasm of gum

MedGen UID:
83856
•Concept ID:
C0347201
•
Neoplastic Process
Synonyms: Benign Gingival Neoplasm; benign gingival neoplasm; Benign Gingival Tumor; benign gingival tumor; benign gingival tumour; Benign Gum Neoplasm; benign gum neoplasm; Benign Gum Tumor; benign gum tumor; benign gum tumour; Benign Neoplasm of Gingiva; benign neoplasm of gingiva; Benign Neoplasm of Gum; benign neoplasm of gum; Benign Neoplasm of the Gingiva; benign neoplasm of the gingiva; Benign Neoplasm of the Gum; benign neoplasm of the gum; Benign tumor of alveolar mucosa; Benign tumor of gingiva; Benign Tumor of Gingiva; benign tumor of gingiva; Benign tumor of gum; Benign Tumor of Gum; benign tumor of gum; Benign Tumor of the Gingiva; benign tumor of the gingiva; Benign Tumor of the Gum; benign tumor of the gum; benign tumour of gingiva; benign tumour of gum; benign tumour of the gingiva; benign tumour of the gum; gingiva benign neoplasm
SNOMED CT: Benign tumor of gingiva (92126004); Benign tumor of alveolar mucosa (92126004); Benign tumor of gum (92126004); Benign neoplasm of gum (92126004)
 
Monarch Initiative: MONDO:0021491

Definition

A neoplasm that arises from the upper or lower gingiva and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBenign neoplasm of gum

Professional guidelines

PubMed

Traversing the diverse avenues of exopolysaccharides-based nanocarriers in the management of cancer.
Paul P, Nair R, Mahajan S, Gupta U, Aalhate M, Maji I, Singh PK
Carbohydr Polym 2023 Jul 15;312:120821. Epub 2023 Mar 20 doi: 10.1016/j.carbpol.2023.120821. PMID: 37059549
Salivary Gland Hypofunction and/or Xerostomia Induced by Nonsurgical Cancer Therapies: ISOO/MASCC/ASCO Guideline.
Mercadante V, Jensen SB, Smith DK, Bohlke K, Bauman J, Brennan MT, Coppes RP, Jessen N, Malhotra NK, Murphy B, Rosenthal DI, Vissink A, Wu J, Saunders DP, Peterson DE
J Clin Oncol 2021 Sep 1;39(25):2825-2843. Epub 2021 Jul 20 doi: 10.1200/JCO.21.01208. PMID: 34283635
Stimuli-responsive natural gums-based drug delivery systems for cancer treatment.
Soleimani K, Derakhshankhah H, Jaymand M, Samadian H
Carbohydr Polym 2021 Feb 15;254:117422. Epub 2020 Nov 22 doi: 10.1016/j.carbpol.2020.117422. PMID: 33357903

Recent clinical studies

Etiology

Prophylaxis for mucositis induced by ambulatory chemotherapy: systematic review.
Manzi Nde M, Silveira RC, dos Reis PE
J Adv Nurs 2016 Apr;72(4):735-46. Epub 2015 Dec 2 doi: 10.1111/jan.12867. PMID: 26626711
Understanding bisphosphonates and osteonecrosis of the jaw: uses and risks.
Rosini S, Rosini S, Bertoldi I, Frediani B
Eur Rev Med Pharmacol Sci 2015 Sep;19(17):3309-17. PMID: 26400539
Systematic literature review: xerostomia in advanced cancer patients.
Hanchanale S, Adkinson L, Daniel S, Fleming M, Oxberry SG
Support Care Cancer 2015 Mar;23(3):881-8. Epub 2014 Oct 18 doi: 10.1007/s00520-014-2477-8. PMID: 25322971
Reducing risk in smokers.
Westmaas JL, Brandon TH
Curr Opin Pulm Med 2004 Jul;10(4):284-8. doi: 10.1097/01.mcp.0000128431.72268.4d. PMID: 15220753
Update on contraception.
Wilkinson CL, Stirland AM, Massil H
Int J STD AIDS 1997 Apr;8(4):216-22; quiz 223. doi: 10.1258/0956462971919949. PMID: 9147153

Diagnosis

EVALUATION OF EFFICIENCY OF CHEWING IN PATIENTS WITH ONCOPATHOLOGY OF THE ORAL CAVITY.
Kushta AO
Wiad Lek 2022;75(12):3000-3003. doi: 10.36740/WLek202212118. PMID: 36723317
Gum polysaccharide/nanometal hybrid biocomposites in cancer diagnosis and therapy.
Makvandi P, Baghbantaraghdari Z, Zhou W, Zhang Y, Manchanda R, Agarwal T, Wu A, Maiti TK, Varma RS, Smith BR
Biotechnol Adv 2021 May-Jun;48:107711. Epub 2021 Feb 14 doi: 10.1016/j.biotechadv.2021.107711. PMID: 33592279
Preparation, characterization and therapeutic properties of gum arabic-stabilized gallic acid nanoparticles.
Hassani A, Azarian MMS, Ibrahim WN, Hussain SA
Sci Rep 2020 Oct 20;10(1):17808. doi: 10.1038/s41598-020-71175-8. PMID: 33082415Free PMC Article
Gum hypertrophy.
Gundabolu K, Kong G, Verma A
CMAJ 2009 Feb 17;180(4):471. doi: 10.1503/cmaj.080424. PMID: 19221364Free PMC Article
Reducing risk in smokers.
Westmaas JL, Brandon TH
Curr Opin Pulm Med 2004 Jul;10(4):284-8. doi: 10.1097/01.mcp.0000128431.72268.4d. PMID: 15220753

Therapy

Functional Components of Carob Fruit: Linking the Chemical and Biological Space.
Goulas V, Stylos E, Chatziathanasiadou MV, Mavromoustakos T, Tzakos AG
Int J Mol Sci 2016 Nov 10;17(11) doi: 10.3390/ijms17111875. PMID: 27834921Free PMC Article
Guggulsterone for Chemoprevention of Cancer.
Shishodia S, Azu N, Rosenzweig JA, Jackson DA
Curr Pharm Des 2016;22(3):294-306. doi: 10.2174/1381612822666151112153117. PMID: 26561056
Understanding bisphosphonates and osteonecrosis of the jaw: uses and risks.
Rosini S, Rosini S, Bertoldi I, Frediani B
Eur Rev Med Pharmacol Sci 2015 Sep;19(17):3309-17. PMID: 26400539
Cancer chemopreventive and therapeutic potential of guggulsterone.
Almazari I, Surh YJ
Top Curr Chem 2013;329:35-60. doi: 10.1007/128_2012_344. PMID: 22851157
Update on contraception.
Wilkinson CL, Stirland AM, Massil H
Int J STD AIDS 1997 Apr;8(4):216-22; quiz 223. doi: 10.1258/0956462971919949. PMID: 9147153

Prognosis

Salivary Gland Hypofunction and/or Xerostomia Induced by Nonsurgical Cancer Therapies: ISOO/MASCC/ASCO Guideline.
Mercadante V, Jensen SB, Smith DK, Bohlke K, Bauman J, Brennan MT, Coppes RP, Jessen N, Malhotra NK, Murphy B, Rosenthal DI, Vissink A, Wu J, Saunders DP, Peterson DE
J Clin Oncol 2021 Sep 1;39(25):2825-2843. Epub 2021 Jul 20 doi: 10.1200/JCO.21.01208. PMID: 34283635
Effects of racial residential segregation on oral squamous cell carcinoma prognosis and survival.
Harris JA, Hunter WP, Ji YD, Hanna GJ
Oral Oncol 2021 Aug;119:105364. Epub 2021 Jun 3 doi: 10.1016/j.oraloncology.2021.105364. PMID: 34091188
Functional Components of Carob Fruit: Linking the Chemical and Biological Space.
Goulas V, Stylos E, Chatziathanasiadou MV, Mavromoustakos T, Tzakos AG
Int J Mol Sci 2016 Nov 10;17(11) doi: 10.3390/ijms17111875. PMID: 27834921Free PMC Article
Renal and extrarenal effects of gum arabic ( Acacia senegal )--what can be learned from animal experiments?
Nasir O
Kidney Blood Press Res 2013;37(4-5):269-79. Epub 2013 Aug 11 doi: 10.1159/000350152. PMID: 24022265
Contemporary smoking cessation.
Westmaas JL, Nath V, Brandon TH
Cancer Control 2000 Jan-Feb;7(1):56-62. doi: 10.1177/107327480000700105. PMID: 10740661

Clinical prediction guides

Associations between eosinophils and cancer risk in the UK Biobank.
Wang JH, Rabkin CS, Engels EA, Song M
Int J Cancer 2024 Aug 1;155(3):486-492. Epub 2024 May 2 doi: 10.1002/ijc.34986. PMID: 38695391Free PMC Article
Efficacy and Safety of Synbiotics in Patients Undergoing Autologous Hematopoietic Stem Cell Transplantation: A Randomized, Double-blinded, Placebo-controlled Pilot Study.
Mizutani Y, Kawamoto S, Takahashi M, Doi H, Wakida K, Tabuchi S, Tanda M, Soga A, Chijiki R, Takakura H, Kawaguchi K, Higashime A, Watanabe M, Ichikawa H, Matsumoto S, Sakai R, Goto H, Kurata K, Kakiuchi S, Miyata Y, Uryu K, Inui Y, Kitao A, Yakushijin K, Matsuoka H, Minami H
Intern Med 2023 Oct 15;62(20):2949-2958. Epub 2023 Feb 15 doi: 10.2169/internalmedicine.1314-22. PMID: 36792187Free PMC Article
Guar bean in urinary cytology: a morphologic pitfall.
Nomani L, Abro S, Quek ML, Barkan GA
J Am Soc Cytopathol 2021 Jan-Feb;10(1):41-46. Epub 2020 Sep 14 doi: 10.1016/j.jasc.2020.09.001. PMID: 33129759
Pretreatment oral hygiene habits and survival of head and neck squamous cell carcinoma (HNSCC) patients.
Friemel J, Foraita R, Günther K, Heibeck M, Günther F, Pflueger M, Pohlabeln H, Behrens T, Bullerdiek J, Nimzyk R, Ahrens W
BMC Oral Health 2016 Mar 11;16:33. doi: 10.1186/s12903-016-0185-0. PMID: 26969620Free PMC Article
Impact of smoking and smokeless tobacco on the risk of cancer of the head and neck.
Stockwell HG, Lyman GH
Head Neck Surg 1986 Nov-Dec;9(2):104-10. doi: 10.1002/hed.2890090206. PMID: 3623935

Recent systematic reviews

Effect of chewing gum on the management of chemotherapy-induced oral mucositis in children: Systematic review of experimental studies.
Semerci R, Kocaaslan EN
Eur J Cancer Care (Engl) 2022 Nov;31(6):e13727. Epub 2022 Oct 14 doi: 10.1111/ecc.13727. PMID: 36239087
Prophylaxis for mucositis induced by ambulatory chemotherapy: systematic review.
Manzi Nde M, Silveira RC, dos Reis PE
J Adv Nurs 2016 Apr;72(4):735-46. Epub 2015 Dec 2 doi: 10.1111/jan.12867. PMID: 26626711
Systematic literature review: xerostomia in advanced cancer patients.
Hanchanale S, Adkinson L, Daniel S, Fleming M, Oxberry SG
Support Care Cancer 2015 Mar;23(3):881-8. Epub 2014 Oct 18 doi: 10.1007/s00520-014-2477-8. PMID: 25322971
Systematic review of miscellaneous agents for the management of oral mucositis in cancer patients.
Jensen SB, Jarvis V, Zadik Y, Barasch A, Ariyawardana A, Hovan A, Yarom N, Lalla RV, Bowen J, Elad S; Mucositis Study Group of the Multinational Association of Supportive Care in Cancer/International Society of Oral Oncology (MASCC/ISOO)
Support Care Cancer 2013 Nov;21(11):3223-32. Epub 2013 Jul 31 doi: 10.1007/s00520-013-1884-6. PMID: 23900593
Prevention of oral mucositis in children receiving cancer therapy: a systematic review and evidence-based analysis.
Qutob AF, Gue S, Revesz T, Logan RM, Keefe D
Oral Oncol 2013 Feb;49(2):102-7. Epub 2012 Sep 7 doi: 10.1016/j.oraloncology.2012.08.008. PMID: 22959949

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...