U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Pineal gland astrocytoma

MedGen UID:
83711
•Concept ID:
C0280795
•
Neoplastic Process
Synonyms: astrocytoma (excluding glioblastoma) of pineal body; Astrocytoma of Pineal Gland; astrocytoma of pineal gland; Astrocytoma of the Pineal Gland; astrocytoma of the pineal gland; pineal astrocytic tumor; pineal astrocytic tumour; Pineal Astrocytoma; pineal astrocytoma; pineal body astrocytoma; pineal body astrocytoma (excluding glioblastoma); Pineal Gland Astrocytoma; pineal gland astrocytoma
 
Monarch Initiative: MONDO:0003171

Definition

A astrocytoma that involves the pineal body. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPineal gland astrocytoma

Professional guidelines

PubMed

Results of the treatment of pineal tumors in children: the Lyon experience.
Szathmari A, Beuriat PA, Vasiljevic A, Leblond P, Faure-Conter C, Claude L, Di Rocco F, Mottolese C
Childs Nerv Syst 2023 Sep;39(9):2317-2327. Epub 2022 Oct 15 doi: 10.1007/s00381-022-05649-7. PMID: 36242638
Pineal Region Glioblastomas: Clinical Characteristics, Treatment, and Survival Outcome.
Niu X, Wang C, Zhou X, Yang Y, Liu Y, Zhang Y, Mao Q
World Neurosurg 2021 Feb;146:e799-e810. Epub 2020 Nov 10 doi: 10.1016/j.wneu.2020.11.016. PMID: 33186787
Intracranial tumors in childhood--concepts of treatment and prognosis.
Schulte FJ
Neuropediatrics 1984 Feb;15(1):3-12. doi: 10.1055/s-2008-1052332. PMID: 6324015

Recent clinical studies

Etiology

Occipital interhemispheric transtentorial approach in pediatric patients for lesions of the superomedial cerebellum: operative findings and results.
Peters DR, VanHorn T, Karimian B, Wait SD
Childs Nerv Syst 2023 Feb;39(2):491-496. Epub 2022 Nov 16 doi: 10.1007/s00381-022-05761-8. PMID: 36380052
Central nervous system.
Adamson DC, Rasheed BA, McLendon RE, Bigner DD
Cancer Biomark 2010;9(1-6):193-210. doi: 10.3233/CBM-2011-0177. PMID: 22112477
Pineal tumors.
Dahiya S, Perry A
Adv Anat Pathol 2010 Nov;17(6):419-27. doi: 10.1097/PAP.0b013e3181f895a4. PMID: 20966647
Stereotactic radiosurgery for pineal region tumors.
Dempsey PK, Lunsford LD
Neurosurg Clin N Am 1992 Jan;3(1):245-53. PMID: 1633450
Surgical approach to pineal tumours.
Pluchino F, Broggi G, Fornari M, Franzini A, Solero CL, Allegranza A
Acta Neurochir (Wien) 1989;96(1-2):26-31. doi: 10.1007/BF01403491. PMID: 2929390

Diagnosis

Imagery of pineal tumors.
Deiana G, Mottolese C, Hermier M, Louis-Tisserand G, Berthezene Y
Neurochirurgie 2015 Apr-Jun;61(2-3):113-22. Epub 2015 Feb 9 doi: 10.1016/j.neuchi.2014.10.111. PMID: 25676911
Central nervous system.
Adamson DC, Rasheed BA, McLendon RE, Bigner DD
Cancer Biomark 2010;9(1-6):193-210. doi: 10.3233/CBM-2011-0177. PMID: 22112477
Pineal tumors.
Dahiya S, Perry A
Adv Anat Pathol 2010 Nov;17(6):419-27. doi: 10.1097/PAP.0b013e3181f895a4. PMID: 20966647
Pineal tumors.
Baumgartner JE, Edwards MS
Neurosurg Clin N Am 1992 Oct;3(4):853-62. PMID: 1392580
Pineal astrocytoma.
Benjamin JC, Furneaux CE, Scholtz CL
Surg Neurol 1985 Feb;23(2):139-42. doi: 10.1016/0090-3019(85)90331-3. PMID: 3966205

Therapy

Pineal Region Gliomas: A Single-Center Experience with 25 Cases.
Li D, Wen R, Gao Y, Xu Y, Xiong B, Gong F, Wang W
World Neurosurg 2020 Jan;133:e6-e17. Epub 2019 Jul 5 doi: 10.1016/j.wneu.2019.06.189. PMID: 31284062
Pediatric intracranial primary anaplastic ganglioglioma.
Lüdemann W, Banan R, Hartmann C, Bertalanffy H, Di Rocco C
Childs Nerv Syst 2017 Feb;33(2):227-231. Epub 2016 Dec 5 doi: 10.1007/s00381-016-3302-0. PMID: 27921213
Pineal calcification is associated with pediatric primary brain tumor.
Tuntapakul S, Kitkhuandee A, Kanpittaya J, Johns J, Johns NP
Asia Pac J Clin Oncol 2016 Dec;12(4):e405-e410. Epub 2016 Jul 27 doi: 10.1111/ajco.12519. PMID: 27461152
Risperidone: a useful adjunct for behavioural disturbance in primary cerebral tumours.
Lee MA, Leng ME, Tiernan EJ
Palliat Med 2001 May;15(3):255-6. doi: 10.1191/026921601678576248. PMID: 11407197
Delayed cerebral radiation necrosis.
Morris JG, Grattan-Smith P, Panegyres PK, O'Neill P, Soo YS, Langlands AO
Q J Med 1994 Feb;87(2):119-29. PMID: 8153288

Prognosis

Central nervous system.
Adamson DC, Rasheed BA, McLendon RE, Bigner DD
Cancer Biomark 2010;9(1-6):193-210. doi: 10.3233/CBM-2011-0177. PMID: 22112477
Stereotactic radiosurgery for pineal region tumors.
Dempsey PK, Lunsford LD
Neurosurg Clin N Am 1992 Jan;3(1):245-53. PMID: 1633450
Pineal tumors.
Baumgartner JE, Edwards MS
Neurosurg Clin N Am 1992 Oct;3(4):853-62. PMID: 1392580
Surgical approach to pineal tumours.
Pluchino F, Broggi G, Fornari M, Franzini A, Solero CL, Allegranza A
Acta Neurochir (Wien) 1989;96(1-2):26-31. doi: 10.1007/BF01403491. PMID: 2929390
Intracranial tumors in childhood--concepts of treatment and prognosis.
Schulte FJ
Neuropediatrics 1984 Feb;15(1):3-12. doi: 10.1055/s-2008-1052332. PMID: 6324015

Clinical prediction guides

Concomitant, Single Burr Hole Endoscopic Third Ventriculostomy and Tumor Biopsy for Pineal Lesions: Feasibility, Safety, and Benefits.
Leone A, Colamaria A, Fochi NP, Di Napoli V, Blagia M, Sacco M, Winkler G, Spetzger U, Almerayed W, Carbone F
World Neurosurg 2023 May;173:5-11. Epub 2023 Feb 9 doi: 10.1016/j.wneu.2023.01.082. PMID: 36764448
Signaling the Unfolded Protein Response in primary brain cancers.
Le Reste PJ, Avril T, Quillien V, Morandi X, Chevet E
Brain Res 2016 Jul 1;1642:59-69. Epub 2016 Mar 23 doi: 10.1016/j.brainres.2016.03.015. PMID: 27016056
Pathology of pineal region tumors.
Hirato J, Nakazato Y
J Neurooncol 2001 Sep;54(3):239-49. doi: 10.1023/a:1012721723387. PMID: 11767290
Ex vivo pediatric brain tumors express Fas (CD95) and FasL (CD95L) and are resistant to apoptosis induction.
Riffkin CD, Gray AZ, Hawkins CJ, Chow CW, Ashley DM
Neuro Oncol 2001 Oct;3(4):229-40. doi: 10.1093/neuonc/3.4.229. PMID: 11584892Free PMC Article
Surgical approach to pineal tumours.
Pluchino F, Broggi G, Fornari M, Franzini A, Solero CL, Allegranza A
Acta Neurochir (Wien) 1989;96(1-2):26-31. doi: 10.1007/BF01403491. PMID: 2929390

Recent systematic reviews

Primary Gamma Knife Radiosurgery for pineal region tumors: A systematic review and pooled analysis of available literature with histological stratification.
Gagliardi F, De Domenico P, Garbin E, Snider S, Mortini P
J Pineal Res 2023 Dec;75(4):e12910. Epub 2023 Sep 13 doi: 10.1111/jpi.12910. PMID: 37705383

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...