U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Malformations of Cortical Development, Group III

MedGen UID:
827133
•Concept ID:
C3850039
•
Congenital Abnormality
Synonyms: Cortical Malformations, Group III; Malformations Due to Abnormal Postmigrational Development; Malformations Secondary to Abnormal Postmigrational Development

Definition

Cortical malformations secondary to abnormal cortical maturation after CELL MIGRATION in NEUROGENESIS. This group includes injury to the cortex during later stages of cortical development such as POLYMICROGYRIA and focal cortical dysplasias. [from MeSH]

Professional guidelines

PubMed

Multiorgan manifestations of COL4A1 and COL4A2 variants and proposal for a clinical management protocol.
Gasparini S, Balestrini S, Saccaro LF, Bacci G, Panichella G, Montomoli M, Cantalupo G, Bigoni S, Mancano G, Pellacani S, Leuzzi V, Volpi N, Mari F, Melani F, Cavallin M, Pisano T, Porcedda G, Vaglio A, Mei D, Barba C, Parrini E, Guerrini R
Am J Med Genet C Semin Med Genet 2024 Dec;196(4):e32099. Epub 2024 Jul 17 doi: 10.1002/ajmg.c.32099. PMID: 39016117
Prenatal diagnosis of familial porencephaly associated with fetal stroke.
Shields AD, Knutzen D, Khan M, Sobh O, Jacobs K
Ultrasound Obstet Gynecol 2023 Jul;62(1):153-154. doi: 10.1002/uog.26168. PMID: 36722041
Agenesis of the septum pellucidum: Prenatal diagnosis and outcome.
Borkowski-Tillman T, Garcia-Rodriguez R, Viñals F, Branco M, Kradjen-Haratz K, Ben-Sira L, Lerman-Sagie T, Malinger G
Prenat Diagn 2020 May;40(6):674-680. Epub 2020 Mar 31 doi: 10.1002/pd.5663. PMID: 32037567

Recent clinical studies

Etiology

Sturge-Weber Syndrome Is Associated with Cortical Dysplasia ILAE Type IIIc and Excessive Hypertrophic Pyramidal Neurons in Brain Resections for Intractable Epilepsy.
Wang DD, Blümcke I, Coras R, Zhou WJ, Lu DH, Gui QP, Hu JX, Zuo HC, Chen SY, Piao YS
Brain Pathol 2015 May;25(3):248-55. Epub 2014 Oct 30 doi: 10.1111/bpa.12172. PMID: 25040707Free PMC Article
ILAE focal cortical dysplasia type IIIc in the ictal onset zone in epileptic patients with solitary meningioangiomatosis.
Mukae N, Suzuki SO, Morioka T, Murakami N, Hashiguchi K, Shigeto H, Sakata A, Iihara K
Epileptic Disord 2014 Dec;16(4):533-9. doi: 10.1684/epd.2014.0695. PMID: 25366924
Clinicopathological associations in temporal lobe epilepsy patients utilising the current ILAE focal cortical dysplasia classification.
Johnson AM, Sugo E, Barreto D, Cunningham AM, Hiew CC, Lawson JA, Somerville ER, Connolly AM, Bye AM
Epilepsy Res 2014 Oct;108(8):1345-51. Epub 2014 Jul 7 doi: 10.1016/j.eplepsyres.2014.06.013. PMID: 25048307

Diagnosis

ILAE focal cortical dysplasia type IIIc in the ictal onset zone in epileptic patients with solitary meningioangiomatosis.
Mukae N, Suzuki SO, Morioka T, Murakami N, Hashiguchi K, Shigeto H, Sakata A, Iihara K
Epileptic Disord 2014 Dec;16(4):533-9. doi: 10.1684/epd.2014.0695. PMID: 25366924
Clinicopathological associations in temporal lobe epilepsy patients utilising the current ILAE focal cortical dysplasia classification.
Johnson AM, Sugo E, Barreto D, Cunningham AM, Hiew CC, Lawson JA, Somerville ER, Connolly AM, Bye AM
Epilepsy Res 2014 Oct;108(8):1345-51. Epub 2014 Jul 7 doi: 10.1016/j.eplepsyres.2014.06.013. PMID: 25048307

Therapy

Sturge-Weber Syndrome Is Associated with Cortical Dysplasia ILAE Type IIIc and Excessive Hypertrophic Pyramidal Neurons in Brain Resections for Intractable Epilepsy.
Wang DD, Blümcke I, Coras R, Zhou WJ, Lu DH, Gui QP, Hu JX, Zuo HC, Chen SY, Piao YS
Brain Pathol 2015 May;25(3):248-55. Epub 2014 Oct 30 doi: 10.1111/bpa.12172. PMID: 25040707Free PMC Article

Prognosis

Sturge-Weber Syndrome Is Associated with Cortical Dysplasia ILAE Type IIIc and Excessive Hypertrophic Pyramidal Neurons in Brain Resections for Intractable Epilepsy.
Wang DD, Blümcke I, Coras R, Zhou WJ, Lu DH, Gui QP, Hu JX, Zuo HC, Chen SY, Piao YS
Brain Pathol 2015 May;25(3):248-55. Epub 2014 Oct 30 doi: 10.1111/bpa.12172. PMID: 25040707Free PMC Article

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...