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Cardiac Myxoma

MedGen UID:
82658
•Concept ID:
C0262929
•
Neoplastic Process
Synonyms: Endocardial Myxoma; Endocardium, Myxoma; Myxoma of Endocardium; Myxoma of the Endocardium

Definition

A myxoma arising from the endocardium. [from NCI]

Professional guidelines

PubMed

Current challenges in the diagnosis and treatment of cardiac myxoma.
Samanidis G, Khoury M, Balanika M, Perrea DN
Kardiol Pol 2020 Apr 24;78(4):269-277. Epub 2020 Mar 24 doi: 10.33963/KP.15254. PMID: 32207702
Current diagnosis and management of cardiac myxomas.
Jain S, Maleszewski JJ, Stephenson CR, Klarich KW
Expert Rev Cardiovasc Ther 2015 Apr;13(4):369-75. doi: 10.1586/14779072.2015.1024108. PMID: 25797902
Cardiac tumors--diagnosis and surgical treatment.
Hoffmeier A, Sindermann JR, Scheld HH, Martens S
Dtsch Arztebl Int 2014 Mar 21;111(12):205-11. doi: 10.3238/arztebl.2014.0205. PMID: 24717305Free PMC Article

Recent clinical studies

Etiology

Benign incidental cardiac findings in chest and cardiac CT imaging.
Zhao K, Zhang L, Wang L, Zeng J, Zhang Y, Xie X
Br J Radiol 2023 Feb;96(1142):20211302. Epub 2022 Aug 22 doi: 10.1259/bjr.20211302. PMID: 35969186Free PMC Article
Cardiac myxoma and neural crests: a tense relationship.
Presta I, Donato A, Chirchiglia D, Malara N, Donato G
Cardiovasc Pathol 2020 Jan-Feb;44:107163. Epub 2019 Oct 25 doi: 10.1016/j.carpath.2019.107163. PMID: 31760243
Stroke of a cardiac myxoma origin.
Yuan SM, Humuruola G
Rev Bras Cir Cardiovasc 2015 Mar-Apr;30(2):225-34. doi: 10.5935/1678-9741.20150022. PMID: 26107455Free PMC Article
Current diagnosis and management of cardiac myxomas.
Jain S, Maleszewski JJ, Stephenson CR, Klarich KW
Expert Rev Cardiovasc Ther 2015 Apr;13(4):369-75. doi: 10.1586/14779072.2015.1024108. PMID: 25797902
Infected cardiac myxoma.
Nagata T, Totsugawa T, Katayama K, Kuinose M, Yoshitaka H, Uesugi T
J Card Surg 2013 Nov;28(6):682-4. Epub 2013 Aug 11 doi: 10.1111/jocs.12184. PMID: 23931763

Diagnosis

Current challenges in the diagnosis and treatment of cardiac myxoma.
Samanidis G, Khoury M, Balanika M, Perrea DN
Kardiol Pol 2020 Apr 24;78(4):269-277. Epub 2020 Mar 24 doi: 10.33963/KP.15254. PMID: 32207702
Unusual aspects of cardiac myxoma.
Yuan SM, Yan SL, Wu N
Anatol J Cardiol 2017 Mar;17(3):241-247. doi: 10.14744/AnatolJCardiol.2017.7557. PMID: 28321109Free PMC Article
Current diagnosis and management of cardiac myxomas.
Jain S, Maleszewski JJ, Stephenson CR, Klarich KW
Expert Rev Cardiovasc Ther 2015 Apr;13(4):369-75. doi: 10.1586/14779072.2015.1024108. PMID: 25797902
Cutaneous pseudovasculitis.
Carlson JA, Chen KR
Am J Dermatopathol 2007 Feb;29(1):44-55. doi: 10.1097/01.dad.0000245195.35106.3c. PMID: 17284961
Cardiac myxoma.
Attar S, Lee YC, Singleton R, Scherlis L, David R, McLaughlin JS
Ann Thorac Surg 1980 May;29(5):397-405. doi: 10.1016/s0003-4975(10)61667-0. PMID: 7377880

Therapy

Predicting the risk of cardiac myxoma in Carney complex.
Pitsava G, Zhu C, Sundaram R, Mills JL, Stratakis CA
Genet Med 2021 Jan;23(1):80-85. Epub 2020 Sep 7 doi: 10.1038/s41436-020-00956-3. PMID: 32893266Free PMC Article
Intravenous thrombolysis for pure pontine infarcts caused by cardiac myxoma: a case report and literature review.
Dong M, Ge Y, Li J, Fu K, Zhang L, Teng W, Tian L
Int J Neurosci 2020 Jun;130(6):635-641. Epub 2019 Dec 18 doi: 10.1080/00207454.2019.1702537. PMID: 31818173
Mechanical thrombectomy in cardiac myxoma stroke: a case report and review of the literature.
Chung YS, Lee WJ, Hong J, Byun JS, Kim JK, Chae SA
Acta Neurochir (Wien) 2016 Jun;158(6):1083-8. Epub 2016 Apr 4 doi: 10.1007/s00701-016-2780-x. PMID: 27040551
Infected cardiac myxoma.
Nagata T, Totsugawa T, Katayama K, Kuinose M, Yoshitaka H, Uesugi T
J Card Surg 2013 Nov;28(6):682-4. Epub 2013 Aug 11 doi: 10.1111/jocs.12184. PMID: 23931763
Molecular features, markers, drug targets, and prospective targeted therapeutics in cardiac myxoma.
Barh D, Kumar A, Chatterjee S, Liloglou T
Curr Cancer Drug Targets 2009 Sep;9(6):705-16. doi: 10.2174/156800909789271549. PMID: 19754355

Prognosis

Cardiac myxoma: a contemporary multimodality imaging review.
Colin GC, Gerber BL, Amzulescu M, Bogaert J
Int J Cardiovasc Imaging 2018 Nov;34(11):1789-1808. Epub 2018 Jul 4 doi: 10.1007/s10554-018-1396-z. PMID: 29974293
Unusual aspects of cardiac myxoma.
Yuan SM, Yan SL, Wu N
Anatol J Cardiol 2017 Mar;17(3):241-247. doi: 10.14744/AnatolJCardiol.2017.7557. PMID: 28321109Free PMC Article
Infected Cardiac Myxoma: an Updated Review.
Yuan SM
Braz J Cardiovasc Surg 2015 Sep-Oct;30(5):571-8. doi: 10.5935/1678-9741.20140112. PMID: 26735605Free PMC Article
Current diagnosis and management of cardiac myxomas.
Jain S, Maleszewski JJ, Stephenson CR, Klarich KW
Expert Rev Cardiovasc Ther 2015 Apr;13(4):369-75. doi: 10.1586/14779072.2015.1024108. PMID: 25797902
Cardiac myxoma and surgical history.
Read RC
Ann Thorac Surg 1980 May;29(5):395-6. doi: 10.1016/s0003-4975(10)61666-9. PMID: 7377879

Clinical prediction guides

Clinical characteristics and surgical outcomes of cardiac myxoma: A meta-analysis of worldwide experience.
Oktaviono YH, Saputra PBT, Arnindita JN, Afgriyuspita LS, Kurniawan RB, Pasahari D, Milla C, Wungu CDK, Susilo H, Multazam CECZ, Alkaff FF
Eur J Surg Oncol 2024 Feb;50(2):107940. Epub 2023 Dec 30 doi: 10.1016/j.ejso.2023.107940. PMID: 38219702
Benign incidental cardiac findings in chest and cardiac CT imaging.
Zhao K, Zhang L, Wang L, Zeng J, Zhang Y, Xie X
Br J Radiol 2023 Feb;96(1142):20211302. Epub 2022 Aug 22 doi: 10.1259/bjr.20211302. PMID: 35969186Free PMC Article
Current challenges in the diagnosis and treatment of cardiac myxoma.
Samanidis G, Khoury M, Balanika M, Perrea DN
Kardiol Pol 2020 Apr 24;78(4):269-277. Epub 2020 Mar 24 doi: 10.33963/KP.15254. PMID: 32207702
Cardiac myxoma: a contemporary multimodality imaging review.
Colin GC, Gerber BL, Amzulescu M, Bogaert J
Int J Cardiovasc Imaging 2018 Nov;34(11):1789-1808. Epub 2018 Jul 4 doi: 10.1007/s10554-018-1396-z. PMID: 29974293
Mitral valve myxoma: clinical features, current diagnostic approaches, and surgical management.
Yuan SM
Cardiol J 2012;19(1):105-9. doi: 10.5603/cj.2012.0019. PMID: 22298179

Recent systematic reviews

Clinical characteristics and surgical outcomes of cardiac myxoma: A meta-analysis of worldwide experience.
Oktaviono YH, Saputra PBT, Arnindita JN, Afgriyuspita LS, Kurniawan RB, Pasahari D, Milla C, Wungu CDK, Susilo H, Multazam CECZ, Alkaff FF
Eur J Surg Oncol 2024 Feb;50(2):107940. Epub 2023 Dec 30 doi: 10.1016/j.ejso.2023.107940. PMID: 38219702
The benign nature and rare occurrence of cardiac myxoma as a possible consequence of the limited cardiac proliferative/ regenerative potential: a systematic review.
Shafi O, Siddiqui G, Jaffry HA
BMC Cancer 2023 Dec 18;23(1):1245. doi: 10.1186/s12885-023-11723-3. PMID: 38110859Free PMC Article
Risk factors of embolism for the cardiac myxoma patients: a systematic review and metanalysis.
Liu Y, Wang J, Guo L, Ping L
BMC Cardiovasc Disord 2020 Jul 25;20(1):348. doi: 10.1186/s12872-020-01631-w. PMID: 32711463Free PMC Article
Cardiac and vascular causes of persistent fever: A systematic review.
Yuan SM
Rev Cardiovasc Med 2019 Dec 30;20(4):255-261. doi: 10.31083/j.rcm.2019.04.565. PMID: 31912716
Infected Cardiac Myxoma: an Updated Review.
Yuan SM
Braz J Cardiovasc Surg 2015 Sep-Oct;30(5):571-8. doi: 10.5935/1678-9741.20140112. PMID: 26735605Free PMC Article

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