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Core binding factor acute myeloid leukemia

MedGen UID:
825586
Concept ID:
C3839741
Neoplastic Process
Synonyms: CBF-AML - core binding factor acute myeloid leukemia; Core Binding Factor Acute Myeloid Leukemia; core binding factor acute myeloid leukemia
SNOMED CT: Core binding factor acute myeloid leukemia (702446006); CBF-AML - core binding factor acute myeloid leukemia (702446006)
 
Monarch Initiative: MONDO:0850269

Definition

Form of acute myeloid leukaemia having a shortage of all types of mature blood cells with onset in childhood or young adulthood. [from SNOMEDCT_US]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCore binding factor acute myeloid leukemia

Professional guidelines

PubMed

Darwish C, Farina K, Tremblay D
Blood Rev 2023 Nov;62:101117. Epub 2023 Jul 25 doi: 10.1016/j.blre.2023.101117. PMID: 37524647
Litzow MR
Haematologica 2020 Jun;105(6):1475-1477. doi: 10.3324/haematol.2020.249110. PMID: 32482754Free PMC Article
Mrózek K, Marcucci G, Paschka P, Bloomfield CD
Curr Opin Oncol 2008 Nov;20(6):711-8. doi: 10.1097/CCO.0b013e32831369df. PMID: 18841055Free PMC Article

Recent clinical studies

Etiology

Darwish C, Farina K, Tremblay D
Blood Rev 2023 Nov;62:101117. Epub 2023 Jul 25 doi: 10.1016/j.blre.2023.101117. PMID: 37524647
Ishikawa Y, Kawashima N, Atsuta Y, Sugiura I, Sawa M, Dobashi N, Yokoyama H, Doki N, Tomita A, Kiguchi T, Koh S, Kanamori H, Iriyama N, Kohno A, Moriuchi Y, Asada N, Hirano D, Togitani K, Sakura T, Hagihara M, Tomikawa T, Yokoyama Y, Asou N, Ohtake S, Matsumura I, Miyazaki Y, Naoe T, Kiyoi H
Blood Adv 2020 Jan 14;4(1):66-75. doi: 10.1182/bloodadvances.2019000709. PMID: 31899799Free PMC Article
Duployez N, Marceau-Renaut A, Boissel N, Petit A, Bucci M, Geffroy S, Lapillonne H, Renneville A, Ragu C, Figeac M, Celli-Lebras K, Lacombe C, Micol JB, Abdel-Wahab O, Cornillet P, Ifrah N, Dombret H, Leverger G, Jourdan E, Preudhomme C
Blood 2016 May 19;127(20):2451-9. Epub 2016 Mar 15 doi: 10.1182/blood-2015-12-688705. PMID: 26980726Free PMC Article
Sinha C, Cunningham LC, Liu PP
Semin Hematol 2015 Jul;52(3):215-22. Epub 2015 Apr 7 doi: 10.1053/j.seminhematol.2015.04.002. PMID: 26111469Free PMC Article
Sangle NA, Perkins SL
Arch Pathol Lab Med 2011 Nov;135(11):1504-9. doi: 10.5858/arpa.2010-0482-RS. PMID: 22032582

Diagnosis

Darwish C, Farina K, Tremblay D
Blood Rev 2023 Nov;62:101117. Epub 2023 Jul 25 doi: 10.1016/j.blre.2023.101117. PMID: 37524647
Ishikawa Y, Kawashima N, Atsuta Y, Sugiura I, Sawa M, Dobashi N, Yokoyama H, Doki N, Tomita A, Kiguchi T, Koh S, Kanamori H, Iriyama N, Kohno A, Moriuchi Y, Asada N, Hirano D, Togitani K, Sakura T, Hagihara M, Tomikawa T, Yokoyama Y, Asou N, Ohtake S, Matsumura I, Miyazaki Y, Naoe T, Kiyoi H
Blood Adv 2020 Jan 14;4(1):66-75. doi: 10.1182/bloodadvances.2019000709. PMID: 31899799Free PMC Article
Sinha C, Cunningham LC, Liu PP
Semin Hematol 2015 Jul;52(3):215-22. Epub 2015 Apr 7 doi: 10.1053/j.seminhematol.2015.04.002. PMID: 26111469Free PMC Article
Sangle NA, Perkins SL
Arch Pathol Lab Med 2011 Nov;135(11):1504-9. doi: 10.5858/arpa.2010-0482-RS. PMID: 22032582
Lim KH, Pardanani A, Tefferi A
Acta Haematol 2008;119(4):194-8. Epub 2008 Jun 20 doi: 10.1159/000140630. PMID: 18566536

Therapy

Darwish C, Farina K, Tremblay D
Blood Rev 2023 Nov;62:101117. Epub 2023 Jul 25 doi: 10.1016/j.blre.2023.101117. PMID: 37524647
Duployez N, Marceau-Renaut A, Boissel N, Petit A, Bucci M, Geffroy S, Lapillonne H, Renneville A, Ragu C, Figeac M, Celli-Lebras K, Lacombe C, Micol JB, Abdel-Wahab O, Cornillet P, Ifrah N, Dombret H, Leverger G, Jourdan E, Preudhomme C
Blood 2016 May 19;127(20):2451-9. Epub 2016 Mar 15 doi: 10.1182/blood-2015-12-688705. PMID: 26980726Free PMC Article
Solh M, Yohe S, Weisdorf D, Ustun C
Am J Hematol 2014 Dec;89(12):1121-31. Epub 2014 Aug 27 doi: 10.1002/ajh.23821. PMID: 25088818
Paschka P, Döhner K
Hematology Am Soc Hematol Educ Program 2013;2013:209-19. doi: 10.1182/asheducation-2013.1.209. PMID: 24319183
Bhatt VR, Kantarjian H, Cortes JE, Ravandi F, Borthakur G
Clin Lymphoma Myeloma Leuk 2013 Apr;13(2):153-8. Epub 2012 Dec 21 doi: 10.1016/j.clml.2012.11.006. PMID: 23266036Free PMC Article

Prognosis

Darwish C, Farina K, Tremblay D
Blood Rev 2023 Nov;62:101117. Epub 2023 Jul 25 doi: 10.1016/j.blre.2023.101117. PMID: 37524647
Ishikawa Y, Kawashima N, Atsuta Y, Sugiura I, Sawa M, Dobashi N, Yokoyama H, Doki N, Tomita A, Kiguchi T, Koh S, Kanamori H, Iriyama N, Kohno A, Moriuchi Y, Asada N, Hirano D, Togitani K, Sakura T, Hagihara M, Tomikawa T, Yokoyama Y, Asou N, Ohtake S, Matsumura I, Miyazaki Y, Naoe T, Kiyoi H
Blood Adv 2020 Jan 14;4(1):66-75. doi: 10.1182/bloodadvances.2019000709. PMID: 31899799Free PMC Article
Duployez N, Marceau-Renaut A, Boissel N, Petit A, Bucci M, Geffroy S, Lapillonne H, Renneville A, Ragu C, Figeac M, Celli-Lebras K, Lacombe C, Micol JB, Abdel-Wahab O, Cornillet P, Ifrah N, Dombret H, Leverger G, Jourdan E, Preudhomme C
Blood 2016 May 19;127(20):2451-9. Epub 2016 Mar 15 doi: 10.1182/blood-2015-12-688705. PMID: 26980726Free PMC Article
Duployez N, Willekens C, Marceau-Renaut A, Boudry-Labis E, Preudhomme C
Expert Rev Hematol 2015 Feb;8(1):43-56. Epub 2014 Oct 28 doi: 10.1586/17474086.2014.976551. PMID: 25348871
Sangle NA, Perkins SL
Arch Pathol Lab Med 2011 Nov;135(11):1504-9. doi: 10.5858/arpa.2010-0482-RS. PMID: 22032582

Clinical prediction guides

Duan W, Liu X, Zhao X, Jia J, Wang J, Gong L, Jiang Q, Zhao T, Wang Y, Zhang X, Xu L, Shi H, Chang Y, Liu K, Huang X, Qin Y, Jiang H
Ann Hematol 2021 May;100(5):1203-1212. Epub 2021 Jan 20 doi: 10.1007/s00277-021-04432-z. PMID: 33474629
Ustun C, Morgan E, Moodie EEM, Pullarkat S, Yeung C, Broesby-Olsen S, Ohgami R, Kim Y, Sperr W, Vestergaard H, Chen D, Kluin PM, Dolan M, Mrózek K, Czuchlewski D, Horny HP, George TI, Kristensen TK, Ku NK, Yi CA, Møller MB, Marcucci G, Baughn L, Schiefer AI, Hilberink JR, Pullarkat V, Shanley R, Kohlschmidt J, Coulombe J, Salhotra A, Soma L, Cho C, Linden MA, Akin C, Gotlib J, Hoermann G, Hornick J, Nakamura R, Deeg J, Bloomfield CD, Weisdorf D, Litzow MR, Valent P, Huls G, Perales MA, Borthakur G
Cancer Med 2018 Sep;7(9):4447-4455. Epub 2018 Aug 16 doi: 10.1002/cam4.1733. PMID: 30117318Free PMC Article
Khan M, Cortes J, Qiao W, Alzubaidi MA, Pierce SA, Ravandi F, Kantarjian HM, Borthakur G
Clin Lymphoma Myeloma Leuk 2018 Jan;18(1):e19-e25. Epub 2017 Sep 25 doi: 10.1016/j.clml.2017.09.017. PMID: 29107583Free PMC Article
Chung C, Ma H
Pharmacotherapy 2017 Sep;37(9):1052-1072. Epub 2017 Jul 31 doi: 10.1002/phar.1977. PMID: 28654205
Duployez N, Marceau-Renaut A, Boissel N, Petit A, Bucci M, Geffroy S, Lapillonne H, Renneville A, Ragu C, Figeac M, Celli-Lebras K, Lacombe C, Micol JB, Abdel-Wahab O, Cornillet P, Ifrah N, Dombret H, Leverger G, Jourdan E, Preudhomme C
Blood 2016 May 19;127(20):2451-9. Epub 2016 Mar 15 doi: 10.1182/blood-2015-12-688705. PMID: 26980726Free PMC Article

Recent systematic reviews

Srinivasan S, Kumar S, Vijayasekharan K, Agrawal AK
Clin Lymphoma Myeloma Leuk 2022 Apr;22(4):e221-e232. Epub 2021 Oct 2 doi: 10.1016/j.clml.2021.09.020. PMID: 34750085
Ayatollahi H, Shajiei A, Sadeghian MH, Sheikhi M, Yazdandoust E, Ghazanfarpour M, Shams SF, Shakeri S
Hematol Oncol Stem Cell Ther 2017 Mar;10(1):1-7. Epub 2016 Sep 3 doi: 10.1016/j.hemonc.2016.08.005. PMID: 27613372
Chen W, Xie H, Wang H, Chen L, Sun Y, Chen Z, Li Q
PLoS One 2016;11(1):e0146614. Epub 2016 Jan 15 doi: 10.1371/journal.pone.0146614. PMID: 26771376Free PMC Article

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