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Delayed Nausea and Vomiting

MedGen UID:
823293
•Concept ID:
C3830545
•
Finding

Definition

Nausea and vomiting occurring more than 24 hours following chemotherapy. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDelayed Nausea and Vomiting

Professional guidelines

PubMed

Management of Chemotherapy-Induced Nausea and Vomiting in Pediatric Patients.
Navari RM
Paediatr Drugs 2017 Jun;19(3):213-222. doi: 10.1007/s40272-017-0228-2. PMID: 28447301
Antiemetic medication for prevention and treatment of chemotherapy-induced nausea and vomiting in childhood.
Phillips RS, Friend AJ, Gibson F, Houghton E, Gopaul S, Craig JV, Pizer B
Cochrane Database Syst Rev 2016 Feb 2;2(2):CD007786. doi: 10.1002/14651858.CD007786.pub3. PMID: 26836199Free PMC Article
Drug treatment of chemotherapy-induced delayed emesis.
Tavorath R, Hesketh PJ
Drugs 1996 Nov;52(5):639-48. doi: 10.2165/00003495-199652050-00002. PMID: 9118814

Recent clinical studies

Etiology

Effect of a Standardized Ginger Root Powder Regimen on Chemotherapy-Induced Nausea and Vomiting: A Multicenter, Double-Blind, Placebo-Controlled Randomized Trial.
Crichton M, Marshall S, Isenring E, Lohning A, McCarthy AL, Molassiotis A, Bird R, Shannon C, Koh A, McPherson I, Marx W
J Acad Nutr Diet 2024 Mar;124(3):313-330.e6. Epub 2023 Sep 10 doi: 10.1016/j.jand.2023.09.003. PMID: 37699474
Delayed nausea and vomiting from carboplatin doublet chemotherapy.
Waqar SN, Mann J, Baggstrom MQ, Waqar MA, Chitneni P, Williams K, Gao F, Morgensztern D, Govindan R
Acta Oncol 2016 Jun;55(6):700-4. Epub 2016 May 4 doi: 10.3109/0284186X.2016.1154603. PMID: 27145068Free PMC Article
Antiemetic medication for prevention and treatment of chemotherapy-induced nausea and vomiting in childhood.
Phillips RS, Friend AJ, Gibson F, Houghton E, Gopaul S, Craig JV, Pizer B
Cochrane Database Syst Rev 2016 Feb 2;2(2):CD007786. doi: 10.1002/14651858.CD007786.pub3. PMID: 26836199Free PMC Article
Controlling emesis: evolving challenges, novel strategies.
Nevidjon B, Chaudhary R
J Support Oncol 2010 Jul-Aug;8(4 Suppl 2):1-10. PMID: 20865953
Aprepitant for chemotherapy-induced nausea and vomiting.
Flemm LA
Clin J Oncol Nurs 2004 Jun;8(3):303-6. doi: 10.1188/04.CJON.303-306. PMID: 15208824

Diagnosis

Delayed nausea and vomiting from carboplatin doublet chemotherapy.
Waqar SN, Mann J, Baggstrom MQ, Waqar MA, Chitneni P, Williams K, Gao F, Morgensztern D, Govindan R
Acta Oncol 2016 Jun;55(6):700-4. Epub 2016 May 4 doi: 10.3109/0284186X.2016.1154603. PMID: 27145068Free PMC Article
Antiemetic medication for prevention and treatment of chemotherapy-induced nausea and vomiting in childhood.
Phillips RS, Friend AJ, Gibson F, Houghton E, Gopaul S, Craig JV, Pizer B
Cochrane Database Syst Rev 2016 Feb 2;2(2):CD007786. doi: 10.1002/14651858.CD007786.pub3. PMID: 26836199Free PMC Article
Controlling emesis: evolving challenges, novel strategies.
Nevidjon B, Chaudhary R
J Support Oncol 2010 Jul-Aug;8(4 Suppl 2):1-10. PMID: 20865953
Antiemetic medication for prevention and treatment of chemotherapy induced nausea and vomiting in childhood.
Phillips RS, Gopaul S, Gibson F, Houghton E, Craig JV, Light K, Pizer B
Cochrane Database Syst Rev 2010 Sep 8;(9):CD007786. doi: 10.1002/14651858.CD007786.pub2. PMID: 20824866
Serotonin receptor antagonists for highly emetogenic chemotherapy in adults.
Billio A, Morello E, Clarke MJ
Cochrane Database Syst Rev 2010 Jan 20;(1):CD006272. doi: 10.1002/14651858.CD006272.pub2. PMID: 20091591

Therapy

Effect of a Standardized Ginger Root Powder Regimen on Chemotherapy-Induced Nausea and Vomiting: A Multicenter, Double-Blind, Placebo-Controlled Randomized Trial.
Crichton M, Marshall S, Isenring E, Lohning A, McCarthy AL, Molassiotis A, Bird R, Shannon C, Koh A, McPherson I, Marx W
J Acad Nutr Diet 2024 Mar;124(3):313-330.e6. Epub 2023 Sep 10 doi: 10.1016/j.jand.2023.09.003. PMID: 37699474
Management of Chemotherapy-Induced Nausea and Vomiting in Pediatric Patients.
Navari RM
Paediatr Drugs 2017 Jun;19(3):213-222. doi: 10.1007/s40272-017-0228-2. PMID: 28447301
Delayed nausea and vomiting from carboplatin doublet chemotherapy.
Waqar SN, Mann J, Baggstrom MQ, Waqar MA, Chitneni P, Williams K, Gao F, Morgensztern D, Govindan R
Acta Oncol 2016 Jun;55(6):700-4. Epub 2016 May 4 doi: 10.3109/0284186X.2016.1154603. PMID: 27145068Free PMC Article
Medicinal plants as antiemetics in the treatment of cancer: a review.
Haniadka R, Popouri S, Palatty PL, Arora R, Baliga MS
Integr Cancer Ther 2012 Mar;11(1):18-28. Epub 2011 Aug 5 doi: 10.1177/1534735411413266. PMID: 21821652
Controlling emesis: evolving challenges, novel strategies.
Nevidjon B, Chaudhary R
J Support Oncol 2010 Jul-Aug;8(4 Suppl 2):1-10. PMID: 20865953

Prognosis

Rolapitant for the prevention of delayed nausea and vomiting over initial and repeat courses of emetogenic chemotherapy.
Rapoport B, van Eeden R, Smit T
Expert Rev Clin Pharmacol 2017 Jan;10(1):17-29. Epub 2016 Dec 15 doi: 10.1080/17512433.2017.1266251. PMID: 27894202
New treatments on the horizon for chemoradiotherapy-induced nausea and vomiting.
Ruhlmann CH, Herrstedt J
Expert Opin Pharmacother 2016 Aug;17(12):1623-9. Epub 2016 Jun 27 doi: 10.1080/14656566.2016.1202923. PMID: 27322893
Incidence of delayed nausea and vomiting in patients with colorectal cancer receiving irinotecan-based chemotherapy.
Hesketh PJ, Bosnjak SM, Nikolic V, Rapoport B
Support Care Cancer 2011 Dec;19(12):2063-6. doi: 10.1007/s00520-011-1286-6. PMID: 21976035
Aprepitant: drug-drug interactions in perspective.
Aapro MS, Walko CM
Ann Oncol 2010 Dec;21(12):2316-2323. Epub 2010 May 20 doi: 10.1093/annonc/mdq149. PMID: 20488873
Aprepitant for chemotherapy-induced nausea and vomiting.
Flemm LA
Clin J Oncol Nurs 2004 Jun;8(3):303-6. doi: 10.1188/04.CJON.303-306. PMID: 15208824

Clinical prediction guides

Effect of a Standardized Ginger Root Powder Regimen on Chemotherapy-Induced Nausea and Vomiting: A Multicenter, Double-Blind, Placebo-Controlled Randomized Trial.
Crichton M, Marshall S, Isenring E, Lohning A, McCarthy AL, Molassiotis A, Bird R, Shannon C, Koh A, McPherson I, Marx W
J Acad Nutr Diet 2024 Mar;124(3):313-330.e6. Epub 2023 Sep 10 doi: 10.1016/j.jand.2023.09.003. PMID: 37699474
Delayed nausea and vomiting from carboplatin doublet chemotherapy.
Waqar SN, Mann J, Baggstrom MQ, Waqar MA, Chitneni P, Williams K, Gao F, Morgensztern D, Govindan R
Acta Oncol 2016 Jun;55(6):700-4. Epub 2016 May 4 doi: 10.3109/0284186X.2016.1154603. PMID: 27145068Free PMC Article
Olanzapine for preventing nausea and vomiting induced by moderately and highly emetogenic chemotherapy.
Wang SY, Yang ZJ, Zhang L
Asian Pac J Cancer Prev 2014;15(22):9587-92. doi: 10.7314/apjcp.2014.15.22.9587. PMID: 25520071
Palonosetron: an evidence-based choice in prevention of nausea and vomiting induced by moderately emetogenic chemotherapy.
Celio L, Agustoni F, Testa I, Dotti K, de Braud F
Tumori 2012 May-Jun;98(3):279-86. doi: 10.1177/030089161209800301. PMID: 22825501
Medicinal plants as antiemetics in the treatment of cancer: a review.
Haniadka R, Popouri S, Palatty PL, Arora R, Baliga MS
Integr Cancer Ther 2012 Mar;11(1):18-28. Epub 2011 Aug 5 doi: 10.1177/1534735411413266. PMID: 21821652

Recent systematic reviews

Prevalence and predictors of long-delayed (> 120 h) chemotherapy-induced nausea and vomiting (CINV)-a systematic review and individual patient data meta-analysis.
Chow R, Yin LB, Baqri W, Huang R, Boldt G, Younus J, Lock M, Prsic E, Zimmermann C, Herrstedt J
Support Care Cancer 2023 Aug 3;31(8):505. doi: 10.1007/s00520-023-07978-y. PMID: 37535218
2016 Updated MASCC/ESMO Consensus Recommendations: Prevention of Nausea and Vomiting Following High Emetic Risk Chemotherapy.
Herrstedt J, Roila F, Warr D, Celio L, Navari RM, Hesketh PJ, Chan A, Aapro MS
Support Care Cancer 2017 Jan;25(1):277-288. Epub 2016 Jul 22 doi: 10.1007/s00520-016-3313-0. PMID: 27443154
Antiemetic medication for prevention and treatment of chemotherapy-induced nausea and vomiting in childhood.
Phillips RS, Friend AJ, Gibson F, Houghton E, Gopaul S, Craig JV, Pizer B
Cochrane Database Syst Rev 2016 Feb 2;2(2):CD007786. doi: 10.1002/14651858.CD007786.pub3. PMID: 26836199Free PMC Article
Prophylaxis of radiation-induced nausea and vomiting using 5-hydroxytryptamine-3 serotonin receptor antagonists: a systematic review of randomized trials.
Salvo N, Doble B, Khan L, Amirthevasar G, Dennis K, Pasetka M, Deangelis C, Tsao M, Chow E
Int J Radiat Oncol Biol Phys 2012 Jan 1;82(1):408-17. Epub 2010 Nov 13 doi: 10.1016/j.ijrobp.2010.08.060. PMID: 21075553
Antiemetic medication for prevention and treatment of chemotherapy induced nausea and vomiting in childhood.
Phillips RS, Gopaul S, Gibson F, Houghton E, Craig JV, Light K, Pizer B
Cochrane Database Syst Rev 2010 Sep 8;(9):CD007786. doi: 10.1002/14651858.CD007786.pub2. PMID: 20824866

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