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Uterine mass

MedGen UID:: 810566
•Concept ID:: C0221782
•: Finding

Synonym:	Mass of uterus
SNOMED CT:	Mass of uterus (129801000119109); Uterine mass (129801000119109)

HPO:	HP:0034881

Definition

A swelling or enlargement localized to the uterus. The word mass is usually used at an early stage of the diagnostic workup before the precise nature of the swelling has been determined. [from HPO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVUterine mass

Abnormality of the genital system
- Abnormal reproductive system morphology
  - Abnormality of the female genitalia
    - Abnormal morphology of female internal genitalia
      - Congenital uterine anomaly
        Abnormal uterus morphology
        Uterine mass

Professional guidelines

PubMed

Leiomyoma or sarcoma? MRI performance in the differential diagnosis of sonographically suspicious uterine masses.

Valletta R, Corato V, Lombardo F, Avesani G, Negri G, Steinkasserer M, Tagliaferri T, Bonatti M
Eur J Radiol 2024 Jan;170:111217. Epub 2023 Nov 25 doi: 10.1016/j.ejrad.2023.111217. PMID: 38042020

Diagnostic accuracy of MRI in the differential diagnosis between uterine leiomyomas and sarcomas: A systematic review and meta-analysis.

Raffone A, Raimondo D, Neola D, Travaglino A, Giorgi M, Lazzeri L, De Laurentiis F, Carravetta C, Zupi E, Seracchioli R, Casadio P, Guida M
Int J Gynaecol Obstet 2024 Apr;165(1):22-33. Epub 2023 Sep 21 doi: 10.1002/ijgo.15136. PMID: 37732472

Accessory Cavitated Uterine Mass: An Emerging Differential Diagnosis of Dysmenorrhea in Adolescents.

Shah N, Joshi A, Bansode S, Bansode V
J Minim Invasive Gynecol 2021 Jun;28(6):1131-1132. Epub 2020 Dec 24 doi: 10.1016/j.jmig.2020.12.021. PMID: 33359290

See all (7)

Recent clinical studies

Etiology

Neutrophil-to-Lymphocyte Ratio (NLR) for Preoperative Differentiation between Uterine Leiomyosarcoma (LMS) and Uterine Leiomyoma: A Case-Controlled Study.

Srisutha P, Santibenchakul S, Ariyasriwatana C, Oranratanaphan S
Asian Pac J Cancer Prev 2023 Feb 1;24(2):701-707. doi: 10.31557/APJCP.2023.24.2.701. PMID: 36853322 Free PMC Article

Preoperative clinical characteristics between uterine sarcoma and leiomyoma in patients with uterine mass, a case-control study.

Chantasartrassamee P, Kongsawatvorakul C, Rermluk N, Charakorn C, Wattanayingcharoenchai R, Lertkhachonsuk AA
Eur J Obstet Gynecol Reprod Biol 2022 Mar;270:176-180. Epub 2022 Jan 17 doi: 10.1016/j.ejogrb.2022.01.013. PMID: 35074691

Molecular biomarkers predicting early development of endometrial carcinoma: A pilot study.

Lupini L, Scutiero G, Iannone P, Martinello R, Bassi C, Ravaioli N, Soave I, Bonaccorsi G, Lanza G, Gafà R, Loizzi V, Negrini M, Greco P
Eur J Cancer Care (Engl) 2019 Nov;28(6):e13137. Epub 2019 Aug 14 doi: 10.1111/ecc.13137. PMID: 31412428

Intracardiac Extension of Intravenous Leiomyomatosis.

Price JD, Anagnostopoulos C, Benvenisty A, Kothuru RK, Balaram SK
Ann Thorac Surg 2017 Feb;103(2):e145-e147. doi: 10.1016/j.athoracsur.2016.07.037. PMID: 28109375

Gestational Trophoblastic Disease Diagnosis Delayed by the Hook Effect.

Cormano J, Mackay G, Holschneider C
Obstet Gynecol 2015 Oct;126(4):811-814. doi: 10.1097/AOG.0000000000000860. PMID: 26132453

See all (67)

Diagnosis

Cornual invasive hydatidiform mole: a rare case report and literature review.

Qian J, Xu S, Chen L
BMC Womens Health 2023 Nov 2;23(1):566. doi: 10.1186/s12905-023-02727-z. PMID: 37919704 Free PMC Article

Accessory Cavitated Uterine Mass: An Emerging Differential Diagnosis of Dysmenorrhea in Adolescents.

Shah N, Joshi A, Bansode S, Bansode V
J Minim Invasive Gynecol 2021 Jun;28(6):1131-1132. Epub 2020 Dec 24 doi: 10.1016/j.jmig.2020.12.021. PMID: 33359290

Benign-looking primary fibrosarcoma of the uterus.

Braun M, Kuncman W, Szumera-Ciećkiewicz A, Koseła-Paterczyk H, Musiał J, Jesionek-Kupnicka D, Ryś J, Kordek R
Pol J Pathol 2019;70(2):148-152. doi: 10.5114/pjp.2019.87108. PMID: 31556568

Wilms Tumor of the Uterus.

Pinto A, Huang M, Castillo RP, Schlumbrecht MP
Int J Gynecol Pathol 2019 Jul;38(4):335-339. doi: 10.1097/PGP.0000000000000500. PMID: 29629978

Incidental uterine mass.

Venkatanarasimha N, Dubbins PA, Freeman SJ
Br J Radiol 2009 Dec;82(984):1043-5. doi: 10.1259/bjr/22167257. PMID: 19934071 Free PMC Article

See all (195)

Therapy

Submucous leiomyoma: an uncommon cause of heavy menstrual bleeding in early adolescence.

David DA, Rodrigues ÂR, Amaral J, Geraldes F
BMJ Case Rep 2024 Mar 27;17(3) doi: 10.1136/bcr-2023-258426. PMID: 38538101 Free PMC Article

Imaging features of accessory cavitated uterine mass (ACUM): a peculiar yet correctable cause of dysmenorrhea.

Gupta S, Manchanda S, Vyas S, Malhotra N, Mathur SR, Kulshrestha V
Abdom Radiol (NY) 2023 Mar;48(3):1100-1106. Epub 2023 Jan 4 doi: 10.1007/s00261-022-03790-0. PMID: 36598568

Uterine metastasis of lung adenocarcinoma under molecular target therapy with epidermal growth factor receptor tyrosine kinase inhibitors: A case report and review of the literature.

Shibata M, Shizu M, Watanabe K, Takeda A
J Obstet Gynaecol Res 2018 Feb;44(2):352-358. Epub 2017 Nov 2 doi: 10.1111/jog.13493. PMID: 29094453

Unusual Causes of Venous Thrombosis: Bladder Distension and Uterine Mass.

Caparelli ML, Perlman S, Lalezari S
Ann Vasc Surg 2018 Jan;46:370.e9-370.e12. Epub 2017 Sep 13 doi: 10.1016/j.avsg.2017.08.046. PMID: 28916305

Iatrogenic implantation of placental tissue after first trimester dilatation and curettage presenting as a uterine mass: A report of two cases.

Topfedaisi Özkan N, Erkan Sarı M, Görkem Ü, Bayramoğlu H, Akbay S, Mutlu Meydanlı M, Güngör T
J Obstet Gynaecol 2017 Aug;37(6):801-803. Epub 2017 Mar 21 doi: 10.1080/01443615.2017.1286301. PMID: 28325128

See all (43)

Prognosis

β-hCG secreting uterine PEComa.

Murphy P, Machlab K, Almohsen S, Fratesi J, Watson G
BMJ Case Rep 2024 Jan 12;17(1) doi: 10.1136/bcr-2023-256641. PMID: 38216169 Free PMC Article

When the uterine mass is not a leiomyoma.

Pereira S, Sousa R, Constantino L, Abrantes C
BMJ Case Rep 2021 Aug 17;14(8) doi: 10.1136/bcr-2021-243845. PMID: 34404659 Free PMC Article

Molecular biomarkers predicting early development of endometrial carcinoma: A pilot study.

Uterine Mass and Menorrhagia: A Rare Presentation of Acute Myeloid Leukemia with Arduous Clinical Course.

Mishra K, Muralidaran C, Jandial A, Mittal BR, Varma S
Balkan Med J 2018 May 29;35(3):282-284. Epub 2017 Dec 8 doi: 10.4274/balkanmedj.2017.0941. PMID: 29219111 Free PMC Article

Recurrent perivascular epithelioid cell tumor of the uterus (PEComa): an immunohistochemical study and review of the literature.

Greene LA, Mount SL, Schned AR, Cooper K
Gynecol Oncol 2003 Sep;90(3):677-81. doi: 10.1016/s0090-8258(03)00325-1. PMID: 13678746

See all (65)

Clinical prediction guides

β-hCG secreting uterine PEComa.

Murphy P, Machlab K, Almohsen S, Fratesi J, Watson G
BMJ Case Rep 2024 Jan 12;17(1) doi: 10.1136/bcr-2023-256641. PMID: 38216169 Free PMC Article

Molecular biomarkers predicting early development of endometrial carcinoma: A pilot study.

Ultrasonographic Findings of Uterine Carcinosarcoma.

Zhao F, Xu Y, Zhang H, Ren Y
Gynecol Obstet Invest 2019;84(3):277-282. Epub 2018 Nov 30 doi: 10.1159/000481885. PMID: 30504724

Treatment of low-grade endometrial stromal sarcoma in a nulligravid woman.

Michael Straughn J Jr, Boitano T, Smith HJ, Dilley SE, Liang MI, Novak L
Gynecol Oncol 2018 Oct;151(1):6-9. Epub 2018 Jun 8 doi: 10.1016/j.ygyno.2018.05.027. PMID: 29887484

Uterine metastasis of lung adenocarcinoma under molecular target therapy with epidermal growth factor receptor tyrosine kinase inhibitors: A case report and review of the literature.

Shibata M, Shizu M, Watanabe K, Takeda A
J Obstet Gynaecol Res 2018 Feb;44(2):352-358. Epub 2017 Nov 2 doi: 10.1111/jog.13493. PMID: 29094453

See all (46)

Recent systematic reviews

Smooth Muscle Tumor of Uncertain Malignant Potential (STUMP): A Systematic Review of the Literature in the Last 20 Years.

Bucuri CE, Ciortea R, Malutan AM, Oprea V, Toma M, Roman MP, Ormindean CM, Nati I, Suciu V, Mihu D
Curr Oncol 2024 Sep 5;31(9):5242-5254. doi: 10.3390/curroncol31090388. PMID: 39330016 Free PMC Article

Diagnostic Accuracy of Ultrasound in the Diagnosis of Uterine Leiomyomas and Sarcomas.

Raffone A, Raimondo D, Neola D, Travaglino A, Raspollini A, Giorgi M, Santoro A, De Meis L, Zannoni GF, Seracchioli R, Casadio P, Guida M
J Minim Invasive Gynecol 2024 Jan;31(1):28-36.e1. Epub 2023 Sep 29 doi: 10.1016/j.jmig.2023.09.013. PMID: 37778636

Diagnostic accuracy of MRI in the differential diagnosis between uterine leiomyomas and sarcomas: A systematic review and meta-analysis.

See all (3)

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Uterine mass

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Clinical resources

Practice guidelines

Consumer resources

Reviews

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