U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Placenta percreta

MedGen UID:
78619
•Concept ID:
C0266766
•
Pathologic Function
Synonyms: Percreta, Placenta; Placenta Percreta
SNOMED CT: Placenta percreta (25585008)
 
HPO: HP:0025653

Definition

Placenta percreta is a rare form of morbidly adherent placenta with penetration through the myometrium reaching serosa and even adjacent pelvic organs. [from HPO]

Professional guidelines

PubMed

Treatment and outcome of placenta percreta: Primary cesarean hysterectomy versus conservative management.
Licon E, Matsuzaki S, Opara KN, Machida H, Roman LD, Sasso EB, Matsuo K
Eur J Obstet Gynecol Reprod Biol 2020 Jan;244:201-203. Epub 2019 Sep 20 doi: 10.1016/j.ejogrb.2019.09.017. PMID: 31627939Free PMC Article
Placenta Accreta Spectrum.
Society of Gynecologic Oncology; American College of Obstetricians and Gynecologists and the Society for Maternal–Fetal Medicine, Cahill AG, Beigi R, Heine RP, Silver RM, Wax JR
Am J Obstet Gynecol 2018 Dec;219(6):B2-B16. doi: 10.1016/j.ajog.2018.09.042. PMID: 30471891
Management of placenta percreta with temporary balloon occlusion of the internal iliac arteries.
Rosner-Tenerowicz A, Pomorski M, Fuchs T, Śliwa J, Pilecka K, Zimmer A, Zimmer M
Eur J Obstet Gynecol Reprod Biol 2018 Jul;226:71-72. Epub 2018 May 14 doi: 10.1016/j.ejogrb.2018.05.014. PMID: 29798808

Recent clinical studies

Etiology

What we know about placenta accreta spectrum (PAS).
Liu X, Wang Y, Wu Y, Zeng J, Yuan X, Tong C, Qi H
Eur J Obstet Gynecol Reprod Biol 2021 Apr;259:81-89. Epub 2021 Feb 6 doi: 10.1016/j.ejogrb.2021.02.001. PMID: 33601317
Special Report of the Society for Maternal-Fetal Medicine Placenta Accreta Spectrum Ultrasound Marker Task Force: Consensus on definition of markers and approach to the ultrasound examination in pregnancies at risk for placenta accreta spectrum.
Shainker SA, Coleman B, Timor-Tritsch IE, Bhide A, Bromley B, Cahill AG, Gandhi M, Hecht JL, Johnson KM, Levine D, Mastrobattista J, Philips J, Platt LD, Shamshirsaz AA, Shipp TD, Silver RM, Simpson LL, Copel JA, Abuhamad A; Society for Maternal-Fetal Medicine. Electronic address: [email protected]
Am J Obstet Gynecol 2021 Jan;224(1):B2-B14. doi: 10.1016/j.ajog.2020.09.001. PMID: 33386103
Placenta Accreta Spectrum.
Society of Gynecologic Oncology; American College of Obstetricians and Gynecologists and the Society for Maternal–Fetal Medicine, Cahill AG, Beigi R, Heine RP, Silver RM, Wax JR
Am J Obstet Gynecol 2018 Dec;219(6):B2-B16. doi: 10.1016/j.ajog.2018.09.042. PMID: 30471891
Obstetric Care Consensus No. 7: Placenta Accreta Spectrum.
American College of Obstetricians and Gynecologists; Society for Maternal-Fetal Medicine
Obstet Gynecol 2018 Dec;132(6):e259-e275. doi: 10.1097/AOG.0000000000002983. PMID: 30461695
The antenatal diagnosis of placenta accreta.
Comstock CH, Bronsteen RA
BJOG 2014 Jan;121(2):171-81; discussion 181-2. doi: 10.1111/1471-0528.12557. PMID: 24373591

Diagnosis

Placenta Accreta Spectrum.
Society of Gynecologic Oncology; American College of Obstetricians and Gynecologists and the Society for Maternal–Fetal Medicine, Cahill AG, Beigi R, Heine RP, Silver RM, Wax JR
Am J Obstet Gynecol 2018 Dec;219(6):B2-B16. doi: 10.1016/j.ajog.2018.09.042. PMID: 30471891
Obstetric Care Consensus No. 7: Placenta Accreta Spectrum.
American College of Obstetricians and Gynecologists; Society for Maternal-Fetal Medicine
Obstet Gynecol 2018 Dec;132(6):e259-e275. doi: 10.1097/AOG.0000000000002983. PMID: 30461695
Outcome of Cesarean scar pregnancy managed expectantly: systematic review and meta-analysis.
Calì G, Timor-Tritsch IE, Palacios-Jaraquemada J, Monteaugudo A, Buca D, Forlani F, Familiari A, Scambia G, Acharya G, D'Antonio F
Ultrasound Obstet Gynecol 2018 Feb;51(2):169-175. doi: 10.1002/uog.17568. PMID: 28661021
Placenta accreta spectrum: pathophysiology and evidence-based anatomy for prenatal ultrasound imaging.
Jauniaux E, Collins S, Burton GJ
Am J Obstet Gynecol 2018 Jan;218(1):75-87. Epub 2017 Jun 24 doi: 10.1016/j.ajog.2017.05.067. PMID: 28599899
The antenatal diagnosis of placenta accreta.
Comstock CH, Bronsteen RA
BJOG 2014 Jan;121(2):171-81; discussion 181-2. doi: 10.1111/1471-0528.12557. PMID: 24373591

Therapy

Special Report of the Society for Maternal-Fetal Medicine Placenta Accreta Spectrum Ultrasound Marker Task Force: Consensus on definition of markers and approach to the ultrasound examination in pregnancies at risk for placenta accreta spectrum.
Shainker SA, Coleman B, Timor-Tritsch IE, Bhide A, Bromley B, Cahill AG, Gandhi M, Hecht JL, Johnson KM, Levine D, Mastrobattista J, Philips J, Platt LD, Shamshirsaz AA, Shipp TD, Silver RM, Simpson LL, Copel JA, Abuhamad A; Society for Maternal-Fetal Medicine. Electronic address: [email protected]
Am J Obstet Gynecol 2021 Jan;224(1):B2-B14. doi: 10.1016/j.ajog.2020.09.001. PMID: 33386103
Minimizing surgical blood loss at cesarean hysterectomy for placenta previa with evidence of placenta increta or placenta percreta: the state of play in 2020.
Kingdom JC, Hobson SR, Murji A, Allen L, Windrim RC, Lockhart E, Collins SL, Soleymani Majd H, Alazzam M, Naaisa F, Shamshirsaz AA, Belfort MA, Fox KA
Am J Obstet Gynecol 2020 Sep;223(3):322-329. Epub 2020 Jan 30 doi: 10.1016/j.ajog.2020.01.044. PMID: 32007492Free PMC Article
Outcome of Cesarean scar pregnancy managed expectantly: systematic review and meta-analysis.
Calì G, Timor-Tritsch IE, Palacios-Jaraquemada J, Monteaugudo A, Buca D, Forlani F, Familiari A, Scambia G, Acharya G, D'Antonio F
Ultrasound Obstet Gynecol 2018 Feb;51(2):169-175. doi: 10.1002/uog.17568. PMID: 28661021
Caesarean scar pregnancy: a precursor of placenta percreta/accreta.
Sinha P, Mishra M
J Obstet Gynaecol 2012 Oct;32(7):621-3. doi: 10.3109/01443615.2012.698665. PMID: 22943704
Placenta percreta revisited.
Khadra M, Obhrai M, Keriakos R, Johanson R
J Obstet Gynaecol 2002 Nov;22(6):689. doi: 10.1080/014436102762062385. PMID: 12554271

Prognosis

Minimizing surgical blood loss at cesarean hysterectomy for placenta previa with evidence of placenta increta or placenta percreta: the state of play in 2020.
Kingdom JC, Hobson SR, Murji A, Allen L, Windrim RC, Lockhart E, Collins SL, Soleymani Majd H, Alazzam M, Naaisa F, Shamshirsaz AA, Belfort MA, Fox KA
Am J Obstet Gynecol 2020 Sep;223(3):322-329. Epub 2020 Jan 30 doi: 10.1016/j.ajog.2020.01.044. PMID: 32007492Free PMC Article
Placenta Accreta Spectrum.
Society of Gynecologic Oncology; American College of Obstetricians and Gynecologists and the Society for Maternal–Fetal Medicine, Cahill AG, Beigi R, Heine RP, Silver RM, Wax JR
Am J Obstet Gynecol 2018 Dec;219(6):B2-B16. doi: 10.1016/j.ajog.2018.09.042. PMID: 30471891
Obstetric Care Consensus No. 7: Placenta Accreta Spectrum.
American College of Obstetricians and Gynecologists; Society for Maternal-Fetal Medicine
Obstet Gynecol 2018 Dec;132(6):e259-e275. doi: 10.1097/AOG.0000000000002983. PMID: 30461695
Perioperative management of a placenta percreta: a case review.
McGarry JR
J Perioper Pract 2015 Sep;25(9):173-5. doi: 10.1177/175045891502500905. PMID: 26677520
The antenatal diagnosis of placenta accreta.
Comstock CH, Bronsteen RA
BJOG 2014 Jan;121(2):171-81; discussion 181-2. doi: 10.1111/1471-0528.12557. PMID: 24373591

Clinical prediction guides

Placenta Accreta Spectrum.
Society of Gynecologic Oncology; American College of Obstetricians and Gynecologists and the Society for Maternal–Fetal Medicine, Cahill AG, Beigi R, Heine RP, Silver RM, Wax JR
Am J Obstet Gynecol 2018 Dec;219(6):B2-B16. doi: 10.1016/j.ajog.2018.09.042. PMID: 30471891
Obstetric Care Consensus No. 7: Placenta Accreta Spectrum.
American College of Obstetricians and Gynecologists; Society for Maternal-Fetal Medicine
Obstet Gynecol 2018 Dec;132(6):e259-e275. doi: 10.1097/AOG.0000000000002983. PMID: 30461695
Outcome of Cesarean scar pregnancy managed expectantly: systematic review and meta-analysis.
Calì G, Timor-Tritsch IE, Palacios-Jaraquemada J, Monteaugudo A, Buca D, Forlani F, Familiari A, Scambia G, Acharya G, D'Antonio F
Ultrasound Obstet Gynecol 2018 Feb;51(2):169-175. doi: 10.1002/uog.17568. PMID: 28661021
Placenta accreta spectrum: pathophysiology and evidence-based anatomy for prenatal ultrasound imaging.
Jauniaux E, Collins S, Burton GJ
Am J Obstet Gynecol 2018 Jan;218(1):75-87. Epub 2017 Jun 24 doi: 10.1016/j.ajog.2017.05.067. PMID: 28599899
The antenatal diagnosis of placenta accreta.
Comstock CH, Bronsteen RA
BJOG 2014 Jan;121(2):171-81; discussion 181-2. doi: 10.1111/1471-0528.12557. PMID: 24373591

Recent systematic reviews

Urological complications in women undergoing Cesarean section for placenta accreta spectrum disorders: systematic review and meta-analysis.
Lucidi A, Jauniaux E, Hussein AM, Coutinho CM, Tinari S, Khalil A, Shamshirsaz A, Palacios-Jaraquemada JM, D'Antonio F
Ultrasound Obstet Gynecol 2023 Nov;62(5):633-643. doi: 10.1002/uog.26299. PMID: 37401769
Diagnostic accuracy of ultrasound in the diagnosis of Placenta accreta spectrum: systematic review and meta-analysis.
Maged AM, El-Mazny A, Kamal N, Mahmoud SI, Fouad M, El-Nassery N, Kotb A, Ragab WS, Ogila AI, Metwally AA, Lasheen Y, Fahmy RM, Katta M, Shaeer EK, Salah N
BMC Pregnancy Childbirth 2023 May 15;23(1):354. doi: 10.1186/s12884-023-05675-6. PMID: 37189095Free PMC Article
Searching for placenta percreta: a prospective cohort and systematic review of case reports.
Jauniaux E, Hecht JL, Elbarmelgy RA, Elbarmelgy RM, Thabet MM, Hussein AM
Am J Obstet Gynecol 2022 Jun;226(6):837.e1-837.e13. Epub 2021 Dec 29 doi: 10.1016/j.ajog.2021.12.030. PMID: 34973177
Conservative management of placenta percreta.
Matsuzaki S, Yoshino K, Endo M, Kakigano A, Takiuchi T, Kimura T
Int J Gynaecol Obstet 2018 Mar;140(3):299-306. Epub 2018 Jan 3 doi: 10.1002/ijgo.12411. PMID: 29194646
Outcome of Cesarean scar pregnancy managed expectantly: systematic review and meta-analysis.
Calì G, Timor-Tritsch IE, Palacios-Jaraquemada J, Monteaugudo A, Buca D, Forlani F, Familiari A, Scambia G, Acharya G, D'Antonio F
Ultrasound Obstet Gynecol 2018 Feb;51(2):169-175. doi: 10.1002/uog.17568. PMID: 28661021

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...