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Non-cardiogenic pulmonary edema

MedGen UID:: 757628
•Concept ID:: C3241936
•: Pathologic Function

Synonyms:	Non-Cardiogenic Pulmonary Edema; Noncardiogenic Pulmonary Edema
SNOMED CT:	Non-cardiogenic pulmonary edema (95437004)

Definition

Pulmonary edema that is not a result of cardiac dysfunction. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVNon-cardiogenic pulmonary edema

Phenotypic abnormality
- Abnormality of the respiratory system
  - Abnormal respiratory system physiology
    - Abnormal respiratory system morphology
      - Abnormality of the lung
        Pulmonary edema
        Non-cardiogenic pulmonary edema

Professional guidelines

PubMed

The Role of Rescue Therapies in the Treatment of Severe ARDS.

Alessandri F, Pugliese F, Ranieri VM
Respir Care 2018 Jan;63(1):92-101. Epub 2017 Oct 24 doi: 10.4187/respcare.05752. PMID: 29066591

Acute lung injury and the acute respiratory distress syndrome: pathophysiology and treatment.

Matuschak GM, Lechner AJ
Mo Med 2010 Jul-Aug;107(4):252-8. PMID: 20806836 Free PMC Article

Do we have a "best practice" for treating high altitude pulmonary edema?

Luks AM
High Alt Med Biol 2008 Summer;9(2):111-4. doi: 10.1089/ham.2008.1017. PMID: 18578641

See all (5)

Recent clinical studies

Etiology

Acute respiratory distress syndrome heterogeneity and the septic ARDS subgroup.

Xu H, Sheng S, Luo W, Xu X, Zhang Z
Front Immunol 2023;14:1277161. Epub 2023 Nov 14 doi: 10.3389/fimmu.2023.1277161. PMID: 38035100 Free PMC Article

Phenotypes and personalized medicine in the acute respiratory distress syndrome.

Matthay MA, Arabi YM, Siegel ER, Ware LB, Bos LDJ, Sinha P, Beitler JR, Wick KD, Curley MAQ, Constantin JM, Levitt JE, Calfee CS
Intensive Care Med 2020 Dec;46(12):2136-2152. Epub 2020 Nov 18 doi: 10.1007/s00134-020-06296-9. PMID: 33206201 Free PMC Article

The unknown known: non-cardiogenic pulmonary edema in amlodipine poisoning, a cohort study.

Lindeman E, Ålebring J, Johansson A, Ahlner J, Kugelberg FC, Nordmark Grass J
Clin Toxicol (Phila) 2020 Nov;58(11):1042-1049. Epub 2020 Mar 2 doi: 10.1080/15563650.2020.1725034. PMID: 32114860

Rickettsial infections.

Olano JP
Ann N Y Acad Sci 2005 Dec;1063:187-96. doi: 10.1196/annals.1355.031. PMID: 16481513

Near-fatal amlodipine poisoning.

Saravu K, Balasubramanian R
J Assoc Physicians India 2004 Feb;52:156-7. PMID: 15656053

See all (37)

Diagnosis

LaGrandeur RG, Tran M, Merchant C, Uy C
J Neonatal Perinatal Med 2017;10(3):339-342. doi: 10.3233/NPM-16107. PMID: 28854506

The effects of opioids on the lung.

Radke JB, Owen KP, Sutter ME, Ford JB, Albertson TE
Clin Rev Allergy Immunol 2014 Feb;46(1):54-64. doi: 10.1007/s12016-013-8373-z. PMID: 23636734

Non-cardiogenic pulmonary edema complicating electroconvulsive therapy: short review of the pathophysiology and diagnostic approach.

Manne JR, Kasirye Y, Epperla N, Garcia-Montilla RJ
Clin Med Res 2012 Aug;10(3):131-6. Epub 2011 Oct 26 doi: 10.3121/cmr.2011.1030. PMID: 22031475 Free PMC Article

Near-fatal amlodipine poisoning.

Saravu K, Balasubramanian R
J Assoc Physicians India 2004 Feb;52:156-7. PMID: 15656053

Pulmonary alterations in cocaine users.

Terra Filho M, Yen CC, Santos Ude P, Muñoz DR
Sao Paulo Med J 2004 Jan 8;122(1):26-31. doi: 10.1590/s1516-31802004000100007. PMID: 15160524 Free PMC Article

See all (36)

Therapy

Acute Respiratory Distress Syndrome.

Williams GW, Berg NK, Reskallah A, Yuan X, Eltzschig HK
Anesthesiology 2021 Feb 1;134(2):270-282. doi: 10.1097/ALN.0000000000003571. PMID: 33016981 Free PMC Article

Hydrochlorothiazide-induced systemic capillary leak.

Vadas P
Am J Emerg Med 2020 Jun;38(6):1299.e1-1299.e2. Epub 2020 Feb 19 doi: 10.1016/j.ajem.2020.02.029. PMID: 32139213

Isolated non-cardiogenic pulmonary edema - A rare complication of MDMA toxicity.

Haaland A, Warman E, Pushkar I, Likourezos A, Friedman MS
Am J Emerg Med 2017 Sep;35(9):1385.e3-1385.e6. Epub 2017 Jun 27 doi: 10.1016/j.ajem.2017.06.040. PMID: 28733094

Clinical images in medical toxicology: heroin overdose with non-cardiogenic pulmonary edema.

Mell HK, Sztajnkrycer MD
Clin Toxicol (Phila) 2006;44(4):399. doi: 10.1080/15563650600671803. PMID: 16809144

Near-fatal amlodipine poisoning.

Saravu K, Balasubramanian R
J Assoc Physicians India 2004 Feb;52:156-7. PMID: 15656053

See all (69)

Prognosis

Acute respiratory distress syndrome heterogeneity and the septic ARDS subgroup.

Xu H, Sheng S, Luo W, Xu X, Zhang Z
Front Immunol 2023;14:1277161. Epub 2023 Nov 14 doi: 10.3389/fimmu.2023.1277161. PMID: 38035100 Free PMC Article

Hydrochlorothiazide-induced systemic capillary leak.

Vadas P
Am J Emerg Med 2020 Jun;38(6):1299.e1-1299.e2. Epub 2020 Feb 19 doi: 10.1016/j.ajem.2020.02.029. PMID: 32139213

What's Next After ARDS: Long-Term Outcomes.

Chiumello D, Coppola S, Froio S, Gotti M
Respir Care 2016 May;61(5):689-99. doi: 10.4187/respcare.04644. PMID: 27121623

Acute lung injury and the acute respiratory distress syndrome: pathophysiology and treatment.

Matuschak GM, Lechner AJ
Mo Med 2010 Jul-Aug;107(4):252-8. PMID: 20806836 Free PMC Article

Near-fatal amlodipine poisoning.

Saravu K, Balasubramanian R
J Assoc Physicians India 2004 Feb;52:156-7. PMID: 15656053

See all (25)

Clinical prediction guides

Unique mutations in mitochondrial DNA and associated pathways involved in high altitude pulmonary edema susceptibility in Indian lowlanders.

Sharma S, Sandhir R, Ganju L, Kumar B, Singh Y
J Biomol Struct Dyn 2023 Jul;41(11):5183-5198. Epub 2022 Jun 6 doi: 10.1080/07391102.2022.2081610. PMID: 35666092

Dengue Hemorrhagic Fever: A State-of-the-Art Review Focused in Pulmonary Involvement.

de Almeida RR, Paim B, de Oliveira SA, Souza AS Jr, Gomes ACP, Escuissato DL, Zanetti G, Marchiori E
Lung 2017 Aug;195(4):389-395. Epub 2017 Jun 13 doi: 10.1007/s00408-017-0021-6. PMID: 28612239 Free PMC Article

Acute lung injury and the acute respiratory distress syndrome: pathophysiology and treatment.

Matuschak GM, Lechner AJ
Mo Med 2010 Jul-Aug;107(4):252-8. PMID: 20806836 Free PMC Article

Hydrochlorothiazide-induced acute non-cardiogenic pulmonary edema.

Gamboa PM, Achotegui V, Irigoyen J, Pérez-Asenjo J, Merino J, Sanz ML
J Investig Allergol Clin Immunol 2005;15(4):299-301. PMID: 16433213

Non-cardiac pulmonary edema following intravenous contrast injection.

Delacour JL, Floriot C, Wagschal G, Daoudal P, Chambers R, Xuan PB
Intensive Care Med 1988;15(1):49-50. doi: 10.1007/BF00255637. PMID: 3230202

See all (15)