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Chronic discoid lupus erythematosus

MedGen UID:
7402
Concept ID:
C0024138
Disease or Syndrome
Synonyms: Discoid Lupus Erythematosus; Lupus Erythematosus, Chronic Cutaneous; Lupus Erythematosus, Cutaneous, Chronic; Lupus Erythematosus, Discoid
SNOMED CT: CDLE - Chronic discoid lupus erythematosus (238927000); Chronic discoid lupus erythematosus (238927000)

Definition

A chronic, autoimmune skin condition that manifests with a red, scaling rash, most often found on the face, ears, and scalp; these lesions often lead to permanent scarring and dyspigmentation. Patients may have lesions with or without other symptoms or antibodies suggestive of systemic lupus erythematosus (SLE). [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVChronic discoid lupus erythematosus
Follow this link to review classifications for Chronic discoid lupus erythematosus in Orphanet.

Professional guidelines

PubMed

TYE MJ, SCHIFF BL, COLLINS SF, BALER GR, APPEL B
N Engl J Med 1954 Jul 8;251(2):52-5. doi: 10.1056/NEJM195407082510202. PMID: 13176652
MARCUS MD, CONRAD AH Jr, WEISS RS
J Invest Dermatol 1953 Aug;21(2):75-7. PMID: 13084968
GOLDMAN L
J Invest Dermatol 1948 Aug;11(2):95. doi: 10.1038/jid.1948.74. PMID: 18877035

Recent clinical studies

Etiology

Gupta U, Barman KD, Saify K
J Dermatol 2005 Dec;32(12):1010-3. doi: 10.1111/j.1346-8138.2005.tb00892.x. PMID: 16471468
Halder RM, Bridgeman-Shah S
Cancer 1995 Jan 15;75(2 Suppl):667-73. doi: 10.1002/1097-0142(19950115)75:2+<667::aid-cncr2820751409>3.0.co;2-i. PMID: 7804993
Thethi CS
Indiana Med 1986 Feb;79(2):150-1. PMID: 3950376
Lindskov R, Reymann F
Dermatologica 1986;172(4):214-7. doi: 10.1159/000249338. PMID: 3519302
DOEGLAS HM
Dermatologica 1963;127:211-5. doi: 10.1159/000254848. PMID: 14051552

Diagnosis

Sehgal VN, Reddy BS, Koranne RV, Sharma AK, Jain RK
J Dermatol 1983 Feb;10(1):81-4. doi: 10.1111/j.1346-8138.1983.tb01108.x. PMID: 6345624
Winkelmann RK
JAMA 1968 Sep 2;205(10):675-8. PMID: 5695138
ROTHFIELD N, MARCH CH, MIESCHER P, MCEWEN C
N Engl J Med 1963 Nov 28;269:1155-61. doi: 10.1056/NEJM196311282692201. PMID: 14061123
SHANON J, RAUBITSCHEK F
Arch Dermatol 1960 Aug;82:268-71. doi: 10.1001/archderm.1960.01580020110029. PMID: 14445488
BENNETT JH, REES RB
Arch Dermatol 1959 Sep;80:339-43. PMID: 13798945

Therapy

McCarthy JT
Arch Dermatol 1971 Jul;104(1):109-10. doi: 10.1001/archderm.104.1.109. PMID: 4256261
Winkelmann RK
JAMA 1968 Sep 2;205(10):675-8. PMID: 5695138
Bjornberg A, Hellgren L
Indian J Dermatol 1966 Oct;12(1):17-8. PMID: 5341750
TYE MJ, SCHIFF BL, COLLINS SF, BALER GR, APPEL B
N Engl J Med 1954 Jul 8;251(2):52-5. doi: 10.1056/NEJM195407082510202. PMID: 13176652
MARCUS MD, CONRAD AH Jr, WEISS RS
J Invest Dermatol 1953 Aug;21(2):75-7. PMID: 13084968

Prognosis

Gupta U, Barman KD, Saify K
J Dermatol 2005 Dec;32(12):1010-3. doi: 10.1111/j.1346-8138.2005.tb00892.x. PMID: 16471468
Thethi CS
Indiana Med 1986 Feb;79(2):150-1. PMID: 3950376
Lindskov R, Reymann F
Dermatologica 1986;172(4):214-7. doi: 10.1159/000249338. PMID: 3519302
Findlay GH, Lups JG
S Afr Med J 1967 Jul 29;41(28):694-8. PMID: 6037854
DOEGLAS HM
Dermatologica 1963;127:211-5. doi: 10.1159/000254848. PMID: 14051552

Clinical prediction guides

Weiss A, Kwon EJ, Kreidel M, Mann R, Cohen JA, Hui Y, Jacobson MI
Am J Dermatopathol 2020 Feb;42(2):129-132. doi: 10.1097/DAD.0000000000001510. PMID: 31464721
Erceg A, De Jong EM, Van Lingen RG, De Boo TM, Van De Kerkhof PC, Seyger MM
J Dermatolog Treat 2009;20(1):32-5. doi: 10.1080/09546630802155040. PMID: 18608708
Kulthanan K, Roongphiboolsopit P, Chanjanakijskul S, Kullavanijaya P
Int J Dermatol 1996 Oct;35(10):711-4. doi: 10.1111/j.1365-4362.1996.tb00643.x. PMID: 8891819
Callen JP
Arch Dermatol 1982 Jun;118(6):412-6. doi: 10.1001/archderm.118.6.412. PMID: 7092253
MUKHERJEE AM, LAHIRI KD, BASU N
Bull Calcutta Sch Trop Med 1963 Apr;11:50-2. PMID: 14299485

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