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Alkylating Agent-Related Acute Myeloid Leukemia

MedGen UID:
730170
•Concept ID:
C1321723
•
Neoplastic Process
Synonym: Alkylating Agent Related Acute Myeloid Leukemia

Definition

Acute myeloid leukemia occurring as late complication of prior therapy with alkylating agents. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAlkylating Agent-Related Acute Myeloid Leukemia

Professional guidelines

PubMed

Risk of acute myelogenous leukaemia and myelodysplasia following cancer treatment.
van Leeuwen FE
Baillieres Clin Haematol 1996 Mar;9(1):57-85. doi: 10.1016/s0950-3536(96)80037-0. PMID: 8730551

Recent clinical studies

Etiology

Dominant and opportunistic leukemic clones: proposal for a pathogenesis-oriented classification in acute myeloid leukemia.
Cucuianu A
Med Hypotheses 2005;65(1):107-13. doi: 10.1016/j.mehy.2004.12.028. PMID: 15893127
Biology and therapy of secondary leukaemias.
Dann EJ, Rowe JM
Best Pract Res Clin Haematol 2001 Mar;14(1):119-37. doi: 10.1053/beha.2000.0119. PMID: 11355927
Risk of acute myelogenous leukaemia and myelodysplasia following cancer treatment.
van Leeuwen FE
Baillieres Clin Haematol 1996 Mar;9(1):57-85. doi: 10.1016/s0950-3536(96)80037-0. PMID: 8730551

Diagnosis

Dominant and opportunistic leukemic clones: proposal for a pathogenesis-oriented classification in acute myeloid leukemia.
Cucuianu A
Med Hypotheses 2005;65(1):107-13. doi: 10.1016/j.mehy.2004.12.028. PMID: 15893127
Biology and therapy of secondary leukaemias.
Dann EJ, Rowe JM
Best Pract Res Clin Haematol 2001 Mar;14(1):119-37. doi: 10.1053/beha.2000.0119. PMID: 11355927

Therapy

Therapy-related myelodysplastic syndrome after eradication of acute promyelocytic leukemia: cytogenetic and molecular features.
Au WY, Lam CC, Ma ES, Man C, Wan T, Kwong YL
Hum Pathol 2001 Jan;32(1):126-9. doi: 10.1053/hupa.2001.21128. PMID: 11172306
Risk of acute myelogenous leukaemia and myelodysplasia following cancer treatment.
van Leeuwen FE
Baillieres Clin Haematol 1996 Mar;9(1):57-85. doi: 10.1016/s0950-3536(96)80037-0. PMID: 8730551

Prognosis

Dominant and opportunistic leukemic clones: proposal for a pathogenesis-oriented classification in acute myeloid leukemia.
Cucuianu A
Med Hypotheses 2005;65(1):107-13. doi: 10.1016/j.mehy.2004.12.028. PMID: 15893127
Biology and therapy of secondary leukaemias.
Dann EJ, Rowe JM
Best Pract Res Clin Haematol 2001 Mar;14(1):119-37. doi: 10.1053/beha.2000.0119. PMID: 11355927
Risk of acute myelogenous leukaemia and myelodysplasia following cancer treatment.
van Leeuwen FE
Baillieres Clin Haematol 1996 Mar;9(1):57-85. doi: 10.1016/s0950-3536(96)80037-0. PMID: 8730551

Clinical prediction guides

Biology and therapy of secondary leukaemias.
Dann EJ, Rowe JM
Best Pract Res Clin Haematol 2001 Mar;14(1):119-37. doi: 10.1053/beha.2000.0119. PMID: 11355927
Risk of acute myelogenous leukaemia and myelodysplasia following cancer treatment.
van Leeuwen FE
Baillieres Clin Haematol 1996 Mar;9(1):57-85. doi: 10.1016/s0950-3536(96)80037-0. PMID: 8730551

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