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Inhalant abuse

MedGen UID:
7083
•Concept ID:
C0021449
•
Mental or Behavioral Dysfunction
Synonyms: Abuse, Inhalant; Abuses, Inhalant; Inhalant Abuse; Inhalant Abuses
SNOMED CT: Inhalant abuse (70340006)

Definition

Illicit use of chemicals and products whose vapors can be inhaled to produce a rapid mind-altering effect. Inhalants include aerosols, gases, and volatile solvents that are often inhaled repeatedly to achieve the short-lived intoxicating effect. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVInhalant abuse

Professional guidelines

PubMed

The Clinical Assessment and Treatment of Inhalant Abuse.
Radparvar S
Perm J 2023 Jun 15;27(2):99-109. Epub 2023 Apr 20 doi: 10.7812/TPP/22.164. PMID: 37078126Free PMC Article
Huffing: prehospital identification & treatment of inhalant abuse.
Criss L
JEMS 2009 May;34(5):42-3, 45, 47 passim. doi: 10.1016/S0197-2510(09)70126-3. PMID: 19433235
Inhalant abuse treatment and prevention.
Public Health Rep 2003 May-Jun;118(3):276. PMID: 12820632Free PMC Article

Recent clinical studies

Etiology

Discriminative Stimulus Effects of Abused Inhalants.
Shelton KL
Curr Top Behav Neurosci 2018;39:113-139. doi: 10.1007/7854_2016_22. PMID: 27714629
Inhalant abuse: youth at risk.
Ahern NR, Falsafi N
J Psychosoc Nurs Ment Health Serv 2013 Aug;51(8):19-24. Epub 2013 Jun 21 doi: 10.3928/02793695-20130612-02. PMID: 23786241
Volatile substance misuse in Mexico: correlates and trends.
Villatoro JA, Cruz SL, Ortiz A, Medina-Mora ME
Subst Use Misuse 2011;46 Suppl 1:40-5. doi: 10.3109/10826084.2011.580205. PMID: 21609144
Nothing to sniff at: inhalant abuse & youth.
McGuinness TM
J Psychosoc Nurs Ment Health Serv 2006 Aug;44(8):15-8. doi: 10.3928/02793695-20060801-03. PMID: 16937770
An overview of inhalant abuse in selected countries of Asia and the Pacific Region.
Kin F, Navaratnam V
NIDA Res Monogr 1995;148:29-49. PMID: 8929883

Diagnosis

Puffy hands and periosteal hyperostosis from inhalant abuse.
Xie C, Fang M
BMJ Case Rep 2020 Jan 26;13(1) doi: 10.1136/bcr-2019-233954. PMID: 31988052Free PMC Article
Inhalant Abuse and Dextromethorphan.
Storck M, Black L, Liddell M
Child Adolesc Psychiatr Clin N Am 2016 Jul;25(3):497-508. doi: 10.1016/j.chc.2016.03.007. PMID: 27338970
Toluene abuse and white matter: a model of toxic leukoencephalopathy.
Filley CM
Psychiatr Clin North Am 2013 Jun;36(2):293-302. Epub 2013 Apr 15 doi: 10.1016/j.psc.2013.02.008. PMID: 23688693
Inhalant abuse.
Muller AA, Muller GF
J Emerg Nurs 2006 Oct;32(5):447-8. Epub 2006 Aug 7 doi: 10.1016/j.jen.2006.05.018. PMID: 16997041
Inhalant abuse.
Espeland K
Lippincotts Prim Care Pract 2000 May-Jun;4(3):336-40. PMID: 11271129

Therapy

Glue sniffing.
Jayanth SH, Hugar BS, Praveen S, Girish Chandra YP
Med Leg J 2017 Mar;85(1):38-42. Epub 2016 Sep 30 doi: 10.1177/0025817216671106. PMID: 27694447
Inhalant Abuse and Dextromethorphan.
Storck M, Black L, Liddell M
Child Adolesc Psychiatr Clin N Am 2016 Jul;25(3):497-508. doi: 10.1016/j.chc.2016.03.007. PMID: 27338970
Inhalant abuse.
Isaacs D, Pigott N
J Paediatr Child Health 2014 Feb;50(2):166. doi: 10.1111/jpc.12524. PMID: 24528449
Inhalant abuse.
Muller AA, Muller GF
J Emerg Nurs 2006 Oct;32(5):447-8. Epub 2006 Aug 7 doi: 10.1016/j.jen.2006.05.018. PMID: 16997041
Inhalant abuse.
Espeland K
Lippincotts Prim Care Pract 2000 May-Jun;4(3):336-40. PMID: 11271129

Prognosis

Butane-related deaths in post-mortem investigations: A systematic review.
Iacoponi N, Del Duca F, Marcacci I, Occhipinti C, Napoletano G, Spadazzi F, La Russa R, Maiese A
Leg Med (Tokyo) 2024 Jul;69:102442. Epub 2024 Mar 30 doi: 10.1016/j.legalmed.2024.102442. PMID: 38579662
Prognosis in substance abuse-related acute toxic leukoencephalopathy: A scoping review.
Macchi ZA, Carlisle TC, Filley CM
J Neurol Sci 2022 Nov 15;442:120420. Epub 2022 Sep 13 doi: 10.1016/j.jns.2022.120420. PMID: 36156344Free PMC Article
Cardiac arrest by inhalation of deodorant spray.
Kramp KH, Salih M, Thomeer E, Gardien M
BMJ Case Rep 2018 Nov 15;2018 doi: 10.1136/bcr-2018-224345. PMID: 30442658Free PMC Article
Toluene abuse and white matter: a model of toxic leukoencephalopathy.
Filley CM
Psychiatr Clin North Am 2013 Jun;36(2):293-302. Epub 2013 Apr 15 doi: 10.1016/j.psc.2013.02.008. PMID: 23688693
Inhalant abuse.
Huxsahl JE
Minn Med 1999 Sep;82(9):46-8. PMID: 10510616

Clinical prediction guides

Assessment of Annual Cost of Substance Use Disorder in US Hospitals.
Peterson C, Li M, Xu L, Mikosz CA, Luo F
JAMA Netw Open 2021 Mar 1;4(3):e210242. doi: 10.1001/jamanetworkopen.2021.0242. PMID: 33666661Free PMC Article
Adolescent inhalant abuse leads to other drug use and impaired growth; implications for diagnosis.
Crossin R, Cairney S, Lawrence AJ, Duncan JR
Aust N Z J Public Health 2017 Feb;41(1):99-104. Epub 2016 Oct 23 doi: 10.1111/1753-6405.12595. PMID: 27774705
Hydrocarbon toxicity: A review.
Tormoehlen LM, Tekulve KJ, Nañagas KA
Clin Toxicol (Phila) 2014 Jun;52(5):479-89. doi: 10.3109/15563650.2014.923904. PMID: 24911841
Determinants of inhalant (whitener) use among street children in a South Indian city.
Praveen D, Maulik PK, Raghavendra B, Khan M, Guggilla RK, Bhatia P
Subst Use Misuse 2012 Aug;47(10):1143-50. Epub 2012 May 18 doi: 10.3109/10826084.2011.644844. PMID: 22607260
Inhalant abuse in pregnancy.
Jones HE, Balster RL
Obstet Gynecol Clin North Am 1998 Mar;25(1):153-67. doi: 10.1016/s0889-8545(05)70363-6. PMID: 9547765

Recent systematic reviews

Butane-related deaths in post-mortem investigations: A systematic review.
Iacoponi N, Del Duca F, Marcacci I, Occhipinti C, Napoletano G, Spadazzi F, La Russa R, Maiese A
Leg Med (Tokyo) 2024 Jul;69:102442. Epub 2024 Mar 30 doi: 10.1016/j.legalmed.2024.102442. PMID: 38579662
Growth changes after inhalant abuse and toluene exposure: A systematic review and meta-analysis of human and animal studies.
Crossin R, Lawrence AJ, Andrews ZB, Churilov L, Duncan JR
Hum Exp Toxicol 2019 Feb;38(2):157-172. Epub 2018 Jul 31 doi: 10.1177/0960327118792064. PMID: 30062923
Psychosocial therapeutic interventions for volatile substance use: a systematic review.
MacLean S, Cameron J, Harney A, Lee NK
Addiction 2012 Feb;107(2):278-88. doi: 10.1111/j.1360-0443.2011.03650.x. PMID: 22248138
Treatment for inhalant dependence and abuse.
Konghom S, Verachai V, Srisurapanont M, Suwanmajo S, Ranuwattananon A, Kimsongneun N, Uttawichai K
Cochrane Database Syst Rev 2010 Dec 8;(12):CD007537. doi: 10.1002/14651858.CD007537.pub2. PMID: 21154379

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