U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Attention Deficit and Disruptive Behavior Disorders

MedGen UID:
68635
•Concept ID:
C0236964
•
Pathologic Function
Synonym: Attention Deficit and Disruptive Behavioral Disorders

Definition

Includes two similar disorders: oppositional defiant disorder and CONDUCT DISORDERS. Symptoms occurring in children with these disorders include: defiance of authority figures, angry outbursts, and other antisocial behaviors. [from MeSH]

Professional guidelines

PubMed

The World Federation of ADHD International Consensus Statement: 208 Evidence-based conclusions about the disorder.
Faraone SV, Banaschewski T, Coghill D, Zheng Y, Biederman J, Bellgrove MA, Newcorn JH, Gignac M, Al Saud NM, Manor I, Rohde LA, Yang L, Cortese S, Almagor D, Stein MA, Albatti TH, Aljoudi HF, Alqahtani MMJ, Asherson P, Atwoli L, Bölte S, Buitelaar JK, Crunelle CL, Daley D, Dalsgaard S, Döpfner M, Espinet S, Fitzgerald M, Franke B, Gerlach M, Haavik J, Hartman CA, Hartung CM, Hinshaw SP, Hoekstra PJ, Hollis C, Kollins SH, Sandra Kooij JJ, Kuntsi J, Larsson H, Li T, Liu J, Merzon E, Mattingly G, Mattos P, McCarthy S, Mikami AY, Molina BSG, Nigg JT, Purper-Ouakil D, Omigbodun OO, Polanczyk GV, Pollak Y, Poulton AS, Rajkumar RP, Reding A, Reif A, Rubia K, Rucklidge J, Romanos M, Ramos-Quiroga JA, Schellekens A, Scheres A, Schoeman R, Schweitzer JB, Shah H, Solanto MV, Sonuga-Barke E, Soutullo C, Steinhausen HC, Swanson JM, Thapar A, Tripp G, van de Glind G, van den Brink W, Van der Oord S, Venter A, Vitiello B, Walitza S, Wang Y
Neurosci Biobehav Rev 2021 Sep;128:789-818. Epub 2021 Feb 4 doi: 10.1016/j.neubiorev.2021.01.022. PMID: 33549739Free PMC Article
Clinical Practice Guideline for the Diagnosis, Evaluation, and Treatment of Attention-Deficit/Hyperactivity Disorder in Children and Adolescents.
Wolraich ML, Hagan JF Jr, Allan C, Chan E, Davison D, Earls M, Evans SW, Flinn SK, Froehlich T, Frost J, Holbrook JR, Lehmann CU, Lessin HR, Okechukwu K, Pierce KL, Winner JD, Zurhellen W; SUBCOMMITTEE ON CHILDREN AND ADOLESCENTS WITH ATTENTION-DEFICIT/HYPERACTIVE DISORDER
Pediatrics 2019 Oct;144(4) doi: 10.1542/peds.2019-2528. PMID: 31570648Free PMC Article
ADHD and behavioral disorders: Assessment, management, and an update from DSM-5.
Austerman J
Cleve Clin J Med 2015 Nov;82(11 Suppl 1):S2-7. doi: 10.3949/ccjm.82.s1.01. PMID: 26555810

Recent clinical studies

Etiology

Oppositional defiant disorder.
Hawes DJ, Gardner F, Dadds MR, Frick PJ, Kimonis ER, Burke JD, Fairchild G
Nat Rev Dis Primers 2023 Jun 22;9(1):31. doi: 10.1038/s41572-023-00441-6. PMID: 37349322
Disruptive Behavior Disorders in Children 0 to 6 Years Old.
Tandon M, Giedinghagen A
Child Adolesc Psychiatr Clin N Am 2017 Jul;26(3):491-502. Epub 2017 Mar 15 doi: 10.1016/j.chc.2017.02.005. PMID: 28577605
Disruptive behavior disorders: taking an RDoC(ish) approach.
Blair RJ, White SF, Meffert H, Hwang S
Curr Top Behav Neurosci 2014;16:319-36. doi: 10.1007/7854_2013_247. PMID: 24048954
Oppositional defiant disorder.
Hamilton SS, Armando J
Am Fam Physician 2008 Oct 1;78(7):861-6. PMID: 18841736
Disruptive behavioral disorders.
Barrickman L
Pediatr Clin North Am 2003 Oct;50(5):1005-17. doi: 10.1016/s0031-3955(03)00078-6. PMID: 14558679

Diagnosis

Oppositional defiant disorder.
Hawes DJ, Gardner F, Dadds MR, Frick PJ, Kimonis ER, Burke JD, Fairchild G
Nat Rev Dis Primers 2023 Jun 22;9(1):31. doi: 10.1038/s41572-023-00441-6. PMID: 37349322
Disruptive Behavior Disorders in Children 0 to 6 Years Old.
Tandon M, Giedinghagen A
Child Adolesc Psychiatr Clin N Am 2017 Jul;26(3):491-502. Epub 2017 Mar 15 doi: 10.1016/j.chc.2017.02.005. PMID: 28577605
Oppositional defiant disorder.
Fraser A, Wray J
Aust Fam Physician 2008 Jun;37(6):402-5. PMID: 18523691
Disruptive behavioral disorders.
Barrickman L
Pediatr Clin North Am 2003 Oct;50(5):1005-17. doi: 10.1016/s0031-3955(03)00078-6. PMID: 14558679
Neuropsychiatric disorders.
Gillberg C
Curr Opin Neurol 1998 Apr;11(2):109-14. doi: 10.1097/00019052-199804000-00005. PMID: 9551289

Therapy

Using antipsychotics for behavioral problems in children.
Shafiq S, Pringsheim T
Expert Opin Pharmacother 2018 Sep;19(13):1475-1488. Epub 2018 Aug 13 doi: 10.1080/14656566.2018.1509069. PMID: 30102079
Atypical antipsychotics for disruptive behaviour disorders in children and youths.
Loy JH, Merry SN, Hetrick SE, Stasiak K
Cochrane Database Syst Rev 2017 Aug 9;8(8):CD008559. doi: 10.1002/14651858.CD008559.pub3. PMID: 28791693Free PMC Article
The Diagnosis and Treatment of Behavioral Disorders in Dementia.
Kratz T
Dtsch Arztebl Int 2017 Jun 30;114(26):447-454. doi: 10.3238/arztebl.2017.0447. PMID: 28705297Free PMC Article
Management of disruptive behavior disorders.
French WP, Kisicki MD
Pediatr Ann 2011 Nov;40(11):563-8. doi: 10.3928/00904481-20111007-07. PMID: 22066508
Fad therapies.
Braganza SF, Ozuah PO
Pediatr Rev 2005 Oct;26(10):371-6. doi: 10.1542/pir.26-10-371. PMID: 16199591

Prognosis

Incidence and comorbidities of disruptive behavior disorders diagnosed in Finnish specialist psychiatric services.
Uotila J, Gyllenberg D, Korhonen L, Hinkka-Yli-Salomäki S, Heinonen E, Chudal R, Gissler M, Sourander A
Soc Psychiatry Psychiatr Epidemiol 2021 Nov;56(11):2063-2072. Epub 2021 Jan 4 doi: 10.1007/s00127-020-02015-3. PMID: 33398496
Viewing preschool disruptive behavior disorders and attention-deficit/hyperactivity disorder through a developmental lens: what we know and what we need to know.
Chacko A, Wakschlag L, Hill C, Danis B, Espy KA
Child Adolesc Psychiatr Clin N Am 2009 Jul;18(3):627-43. doi: 10.1016/j.chc.2009.02.003. PMID: 19486842Free PMC Article
Development and etiology of disruptive and delinquent behavior.
Loeber R, Burke JD, Pardini DA
Annu Rev Clin Psychol 2009;5:291-310. doi: 10.1146/annurev.clinpsy.032408.153631. PMID: 19154139
Attention-deficit/hyperactivity disorder and its comorbidities in women and girls: an evolving picture.
Quinn PO
Curr Psychiatry Rep 2008 Oct;10(5):419-23. doi: 10.1007/s11920-008-0067-5. PMID: 18803916
Risperidone in the management of disruptive behavior disorders.
Pandina GJ, Aman MG, Findling RL
J Child Adolesc Psychopharmacol 2006 Aug;16(4):379-92. doi: 10.1089/cap.2006.16.379. PMID: 16958564

Clinical prediction guides

Psychiatric comorbidities of children with elimination disorders.
Gizli Çoban Ö, Önder A, Sürer Adanır A
Arch Pediatr 2021 Jan;28(1):59-63. Epub 2020 Nov 19 doi: 10.1016/j.arcped.2020.10.002. PMID: 33223199
Disentangling Heterogeneity of Childhood Disruptive Behavior Problems Into Dimensions and Subgroups.
Bolhuis K, Lubke GH, van der Ende J, Bartels M, van Beijsterveldt CEM, Lichtenstein P, Larsson H, Jaddoe VWV, Kushner SA, Verhulst FC, Boomsma DI, Tiemeier H
J Am Acad Child Adolesc Psychiatry 2017 Aug;56(8):678-686. Epub 2017 Jun 29 doi: 10.1016/j.jaac.2017.05.019. PMID: 28735697
Symptom dimensions of disruptive behavior disorders in adolescent drivers.
Garner AA, Gentry A, Welburn SC, Fine PR, Franklin CA, Stavrinos D
J Atten Disord 2014 Aug;18(6):496-503. Epub 2012 Apr 27 doi: 10.1177/1087054711431699. PMID: 22544387
Development and etiology of disruptive and delinquent behavior.
Loeber R, Burke JD, Pardini DA
Annu Rev Clin Psychol 2009;5:291-310. doi: 10.1146/annurev.clinpsy.032408.153631. PMID: 19154139
Oppositional defiant disorder: information for school nurses.
Barcalow K
J Sch Nurs 2006 Feb;22(1):9-16. doi: 10.1177/10598405060220010301. PMID: 16435925

Recent systematic reviews

A Systematic Review of Multiple Family Factors Associated with Oppositional Defiant Disorder.
Lin X, He T, Heath M, Chi P, Hinshaw S
Int J Environ Res Public Health 2022 Aug 31;19(17) doi: 10.3390/ijerph191710866. PMID: 36078582Free PMC Article
Atypical antipsychotics for disruptive behaviour disorders in children and youths.
Loy JH, Merry SN, Hetrick SE, Stasiak K
Cochrane Database Syst Rev 2017 Aug 9;8(8):CD008559. doi: 10.1002/14651858.CD008559.pub3. PMID: 28791693Free PMC Article
The pharmacological management of oppositional behaviour, conduct problems, and aggression in children and adolescents with attention-deficit hyperactivity disorder, oppositional defiant disorder, and conduct disorder: a systematic review and meta-analysis. Part 1: psychostimulants, alpha-2 agonists, and atomoxetine.
Pringsheim T, Hirsch L, Gardner D, Gorman DA
Can J Psychiatry 2015 Feb;60(2):42-51. doi: 10.1177/070674371506000202. PMID: 25886655Free PMC Article
Disruptive behaviour disorders: a systematic review of environmental antenatal and early years risk factors.
Latimer K, Wilson P, Kemp J, Thompson L, Sim F, Gillberg C, Puckering C, Minnis H
Child Care Health Dev 2012 Sep;38(5):611-28. Epub 2012 Feb 28 doi: 10.1111/j.1365-2214.2012.01366.x. PMID: 22372737
Systematic review of pharmacotherapy of disruptive behavior disorders in children and adolescents.
Ipser J, Stein DJ
Psychopharmacology (Berl) 2007 Mar;191(1):127-40. Epub 2006 Sep 16 doi: 10.1007/s00213-006-0537-6. PMID: 16983542

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...