Full Report

Format

Full Report
Summary (Text)
Summary (XML)

Send to:

Choose Destination

File
Clipboard
Collections

Chronic schizophrenia

MedGen UID:: 66383
•Concept ID:: C0221765
•: Mental or Behavioral Dysfunction

Synonym:	Chronic Schizophrenia
SNOMED CT:	Chronic schizophrenia (83746006)

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVChronic schizophrenia

Abnormality of the nervous system
- Abnormal nervous system physiology
  - Abnormality of mental function
    - Atypical behavior
      - Diagnostic behavioral phenotype
        Schizophrenia
        Chronic schizophrenia
        Chronic residual schizophrenia
        Latent Chronic Schizophrenia

Professional guidelines

PubMed

Associations of the Gut Microbiome With Treatment Resistance in Schizophrenia.

Vasileva SS, Yang Y, Baker A, Siskind D, Gratten J, Eyles D
JAMA Psychiatry 2024 Mar 1;81(3):292-302. doi: 10.1001/jamapsychiatry.2023.5371. PMID: 38294805 Free PMC Article

Treatment of chronic schizophrenia with tri-iodothyronine.

Simpson GM, Amuso D
Can Psychiatr Assoc J 1966 Aug;11(4):303-5. doi: 10.1177/070674376601100406. PMID: 5967398

A clinical trial of 'stelazine' in the treatment of chronic schizophrenia.

BATT JC
Postgrad Med J 1959 Oct;35(408):571-4. doi: 10.1136/pgmj.35.408.571. PMID: 13797534 Free PMC Article

See all (181)

Recent clinical studies

Etiology

On the relation of gyrification and cortical thickness alterations to the suicidal risk and mental pain in chronic schizophrenia outpatients.

Bohaterewicz B, Sobczak AM, Krześniak A, Mętel D, Adamczyk P
Psychiatry Res Neuroimaging 2021 Oct 30;316:111343. Epub 2021 Jul 30 doi: 10.1016/j.pscychresns.2021.111343. PMID: 34399285

Age, mortality and chronic schizophrenia.

Black DW, Winokur G
Schizophr Res 1988 Jul-Aug;1(4):267-72. doi: 10.1016/0920-9964(88)90002-3. PMID: 3154513

Depression in chronic schizophrenia.

Roy A, Thompson R, Kennedy S
Br J Psychiatry 1983 May;142:465-70. doi: 10.1192/bjp.142.5.465. PMID: 6871560

Anhedonia and schizophrenia.

Harrow M, Grinker RR, Holzman PS, Kayton L
Am J Psychiatry 1977 Jul;134(7):794-7. doi: 10.1176/ajp.134.7.794. PMID: 869058

Cerebral ventricular size and cognitive impairment in chronic schizophrenia.

Johnstone EC, Crow TJ, Frith CD, Husband J, Kreel L
Lancet 1976 Oct 30;2(7992):924-6. doi: 10.1016/s0140-6736(76)90890-4. PMID: 62160

See all (1611)

Diagnosis

Chronic Schizophrenia Later Diagnosed with Anti-NMDA Receptor Encephalitis: Case Report and Review of the Literature.

Conroy MA, Finch T, Levin TT, Merkler AE, Safdieh J, Samuels S, Gordon Elliott JS
Clin Schizophr Relat Psychoses 2018 Jan;11(4):201-204. Epub 2017 Aug 4 doi: 10.3371/CSRP.MCTF.071317. PMID: 28777034

Delusions of pregnancy.

Michael A, Joseph A, Pallen A
Br J Psychiatry 1994 Feb;164(2):244-6. doi: 10.1192/bjp.164.2.244. PMID: 8173828

Chronic palinopsia in schizophrenia.

Marneros A, Körner J
Psychopathology 1993;26(5-6):236-9. doi: 10.1159/000284828. PMID: 8190842

Cognitive functioning and symptomatology in chronic schizophrenia.

Nelson HE, Pantelis C, Carruthers K, Speller J, Baxendale S, Barnes TR
Psychol Med 1990 May;20(2):357-65. doi: 10.1017/s0033291700017670. PMID: 2356261

Cerebral ventricular size and cognitive impairment in chronic schizophrenia.

Johnstone EC, Crow TJ, Frith CD, Husband J, Kreel L
Lancet 1976 Oct 30;2(7992):924-6. doi: 10.1016/s0140-6736(76)90890-4. PMID: 62160

See all (1195)

Therapy

Physical Activity Diminishes Symptomatic Decline in Chronic Schizophrenia: A Systematic Review.

Tarpada SP, Morris MT
Psychopharmacol Bull 2017 Sep 15;47(4):29-40. PMID: 28936008 Free PMC Article

The Use of Long-Acting Injectable Antipsychotics in Schizophrenia: Evaluating the Evidence.

Correll CU, Citrome L, Haddad PM, Lauriello J, Olfson M, Calloway SM, Kane JM
J Clin Psychiatry 2016;77(suppl 3):1-24. doi: 10.4088/JCP.15032su1. PMID: 27732772

Effectiveness of antipsychotic drugs in patients with chronic schizophrenia: efficacy, safety and cost outcomes of CATIE and other trials.

Lieberman JA
J Clin Psychiatry 2007 Feb;68(2):e04. doi: 10.4088/jcp.0207e04. PMID: 17335312

Aripiprazole.

McGavin JK, Goa KL
CNS Drugs 2002;16(11):779-86; discussion 787-8. doi: 10.2165/00023210-200216110-00008. PMID: 12383035

Clinical review of risperidone.

Chouinard G, Arnott W
Can J Psychiatry 1993 Sep;38 Suppl 3:S89-95. PMID: 7504574

See all (1451)

Prognosis

Mondragón-Maya A, Flores-Medina Y, González-Sánchez D, Hernández-Echeagaray E
Actas Esp Psiquiatr 2023 Jul;51(4):176-183. Epub 2023 Jul 1 PMID: 37817737 Free PMC Article

Abnormalities in the evoked frontal oscillatory activity of first-episode psychosis: A TMS/EEG study.

Ferrarelli F, Kaskie RE, Graziano B, Reis CC, Casali AG
Schizophr Res 2019 Apr;206:436-439. Epub 2018 Nov 23 doi: 10.1016/j.schres.2018.11.008. PMID: 30473213

Neuroimaging and treatment evidence for clinical staging in psychotic disorders: from the at-risk mental state to chronic schizophrenia.

Wood SJ, Yung AR, McGorry PD, Pantelis C
Biol Psychiatry 2011 Oct 1;70(7):619-25. Epub 2011 Jul 18 doi: 10.1016/j.biopsych.2011.05.034. PMID: 21762875

Self-mutilation with needles.

Peschel O, Betz P, Eisenmenger W
Med Sci Law 1997 Apr;37(2):175-8. doi: 10.1177/002580249703700215. PMID: 9149514

Treatment programme and long-term outcome in chronic schizophrenia.

Kane JM
Acta Psychiatr Scand Suppl 1990;358:151-7. doi: 10.1111/j.1600-0447.1990.tb05309.x. PMID: 1978476

See all (684)

Clinical prediction guides

Narrative enhancement and cognitive therapy for perceived stigma of chronic schizophrenia: A multicenter randomized controlled trial study.

Huang LT, Liu CY, Yang CY
Arch Psychiatr Nurs 2023 Jun;44:59-68. Epub 2023 Apr 15 doi: 10.1016/j.apnu.2023.04.004. PMID: 37197864

Physical Activity Diminishes Symptomatic Decline in Chronic Schizophrenia: A Systematic Review.

Tarpada SP, Morris MT
Psychopharmacol Bull 2017 Sep 15;47(4):29-40. PMID: 28936008 Free PMC Article

Negative symptoms in chronic schizophrenia. Relationship to duration of illness.

Ring N, Tantam D, Montague L, Morris J
Br J Psychiatry 1991 Oct;159:495-9. doi: 10.1192/bjp.159.4.495. PMID: 1751858

Cognitive functioning and symptomatology in chronic schizophrenia.

Nelson HE, Pantelis C, Carruthers K, Speller J, Baxendale S, Barnes TR
Psychol Med 1990 May;20(2):357-65. doi: 10.1017/s0033291700017670. PMID: 2356261

Chronic schizophrenia.

Morgan R
Br J Hosp Med 1985 Oct;34(4):202-5. PMID: 2868767

See all (1294)

Recent systematic reviews

Antipsychotic-induced akathisia in adults with acute schizophrenia: A systematic review and dose-response meta-analysis.

Wu H, Siafis S, Wang D, Burschinski A, Schneider-Thoma J, Priller J, Davis JM, Leucht S
Eur Neuropsychopharmacol 2023 Jul;72:40-49. Epub 2023 Apr 17 doi: 10.1016/j.euroneuro.2023.03.015. PMID: 37075639

Alteration patterns of peripheral concentrations of cytokines and associated inflammatory proteins in acute and chronic stages of schizophrenia: a systematic review and network meta-analysis.

Halstead S, Siskind D, Amft M, Wagner E, Yakimov V, Shih-Jung Liu Z, Walder K, Warren N
Lancet Psychiatry 2023 Apr;10(4):260-271. Epub 2023 Feb 27 doi: 10.1016/S2215-0366(23)00025-1. PMID: 36863384

A systematic review of TMS and neurophysiological biometrics in patients with schizophrenia.

di Hou M, Santoro V, Biondi A, Shergill SS, Premoli I
J Psychiatry Neurosci 2021 Nov-Dec;46(6):E675-E701. Epub 2021 Dec 21 doi: 10.1503/jpn.210006. PMID: 34933940 Free PMC Article

Antipsychotic-induced extrapyramidal side effects: A systematic review and meta-analysis of observational studies.

Ali T, Sisay M, Tariku M, Mekuria AN, Desalew A
PLoS One 2021;16(9):e0257129. Epub 2021 Sep 10 doi: 10.1371/journal.pone.0257129. PMID: 34506552 Free PMC Article

A systematic review and meta-analysis of cognitive remediation in early schizophrenia.

Revell ER, Neill JC, Harte M, Khan Z, Drake RJ
Schizophr Res 2015 Oct;168(1-2):213-22. Epub 2015 Aug 21 doi: 10.1016/j.schres.2015.08.017. PMID: 26305063

See all (38)

MedGen

National Center for Biotechnology Information