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Penile sarcoma

MedGen UID:
65960
•Concept ID:
C0238352
•
Neoplastic Process
Synonyms: Penile Sarcoma; penile sarcoma; penis sarcoma; Sarcoma of Penis; sarcoma of penis; Sarcoma of the Penis; sarcoma of the penis
 
Monarch Initiative: MONDO:0001387

Definition

A malignant mesenchymal neoplasm that arises from the penis. Representative examples include Kaposi sarcoma, leiomyosarcoma, and angiosarcoma. [from NCI]

Professional guidelines

PubMed

Surgical Management of Primary Scrotal Cancer.
Huang JH, Broggi M, Osunkoya AO, Master VA
Urol Clin North Am 2016 Nov;43(4):531-544. Epub 2016 Sep 3 doi: 10.1016/j.ucl.2016.06.014. PMID: 27717439
Erectile function after treatment for rhabdomyosarcoma of prostate and bladder.
Frees S, Rubenwolf P, Ziesel C, Faber J, Gutjahr P, Grossmann A, Thüroff JW, Stein R
J Pediatr Urol 2016 Dec;12(6):404.e1-404.e6. Epub 2016 Aug 1 doi: 10.1016/j.jpurol.2016.07.002. PMID: 27570092
Leiomyosarcoma of the penis: a clinicopathologic study of 14 cases with review of the literature and discussion of the differential diagnosis.
Fetsch JF, Davis CJ Jr, Miettinen M, Sesterhenn IA
Am J Surg Pathol 2004 Jan;28(1):115-25. doi: 10.1097/00000478-200401000-00014. PMID: 14707873

Recent clinical studies

Diagnosis

NUTM1-fusion positive malignant neoplasms of the genitourinary tract: A report of six cases highlighting involvement of unusual anatomic locations and histologic heterogeneity.
Xu B, Chen JF, Sarungbam J, Tickoo S, Dickson BC, Reuter VE, Antonescu CR
Genes Chromosomes Cancer 2022 Sep;61(9):542-550. Epub 2022 Apr 27 doi: 10.1002/gcc.23046. PMID: 35430756Free PMC Article
Fibrosarcoma of the corpus cavernosum: case report and literature review.
Liu Z, Zou W
BMC Surg 2021 Jan 6;21(1):20. doi: 10.1186/s12893-020-01006-0. PMID: 33407309Free PMC Article
Epitheloid sarcoma masquerading as Peyronie's disease.
Moore SW, Wheeler JE, Hefter LG
Cancer 1975 Jun;35(6):1706-10. doi: 10.1002/1097-0142(197506)35:6<1706::aid-cncr2820350633>3.0.co;2-a. PMID: 1149001

Prognosis

Fibrosarcoma of the corpus cavernosum: case report and literature review.
Liu Z, Zou W
BMC Surg 2021 Jan 6;21(1):20. doi: 10.1186/s12893-020-01006-0. PMID: 33407309Free PMC Article
Micaceous and keratotic pseudoepitheliomatous balanitis and rapidly fatal fibrosarcoma of the penis occurring in the same patient.
Irvine C, Anderson JR, Pye RJ
Br J Dermatol 1987 May;116(5):719-25. doi: 10.1111/j.1365-2133.1987.tb05907.x. PMID: 3593636

Clinical prediction guides

A Case Study of a Rare Undifferentiated Spindle Cell Sarcoma of the Penis: Establishment and Characterization of Patient-Derived Models.
Sousa ACDS, Fernandes BLNC, da Silva JPA, Stevanato Filho PR, Coimbra LBCT, de Oliveira Beserra A, Alvarenga AL, Maida G, Guimaraes CT, Nakamuta IM, Marchi FA, Alves C, Lichtenfels M, de Farias CB, Kupper BEC, Costa FD, de Mello CAL, Carraro DM, Torrezan GT, Lopes A, Dos Santos TG
Genes (Basel) 2024 Mar 28;15(4) doi: 10.3390/genes15040424. PMID: 38674359Free PMC Article

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