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Congenital candidiasis

MedGen UID:
575892
•Concept ID:
C0343875
•
Disease or Syndrome
Synonyms: Congenital Candidiasis; congenital candidiasis; Congenital candidosis
SNOMED CT: Congenital candidiasis (276672007); Congenital candidosis (276672007)
 
Monarch Initiative: MONDO:0023415

Definition

A fungal infection by any of the Candida species that is present at birth. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCongenital candidiasis

Professional guidelines

PubMed

Advances in pharmacotherapeutic management of common skin diseases in neonates and infants.
Patrizi A, Neri I, Ricci G, Cipriani F, Ravaioli GM
Expert Opin Pharmacother 2017 May;18(7):717-725. Epub 2017 Apr 21 doi: 10.1080/14656566.2017.1316371. PMID: 28429969
Opportunistic invasive fungal infections: diagnosis & clinical management.
Badiee P, Hashemizadeh Z
Indian J Med Res 2014 Feb;139(2):195-204. PMID: 24718393Free PMC Article
Pustular skin disorders: diagnosis and treatment.
Mengesha YM, Bennett ML
Am J Clin Dermatol 2002;3(6):389-400. doi: 10.2165/00128071-200203060-00003. PMID: 12113648

Recent clinical studies

Etiology

Early-Onset Invasive Candidiasis in Extremely Low Birth Weight Infants: Perinatal Acquisition Predicts Poor Outcome.
Barton M, Shen A, O'Brien K, Robinson JL, Davies HD, Simpson K, Asztalos E, Langley J, Le Saux N, Sauve R, Synnes A, Tan B, de Repentigny L, Rubin E, Hui C, Kovacs L, Yau YC, Richardson SE; Paediatric Investigators Collaborative Network on Infections in Canada (PICNIC)
Clin Infect Dis 2017 Apr 1;64(7):921-927. doi: 10.1093/cid/cix001. PMID: 28077516
Congenital candidiasis as a subject of research in medicine and human ecology.
Skoczylas MM, Walat A, Kordek A, Loniewska B, Rudnicki J, Maleszka R, Torbé A
Ann Parasitol 2014;60(3):179-89. PMID: 25281815
Neonatal cutaneous fungal infections.
Smolinski KN, Shah SS, Honig PJ, Yan AC
Curr Opin Pediatr 2005 Aug;17(4):486-93. doi: 10.1097/01.mop.0000171320.91677.55. PMID: 16012261
Mucocutaneous candidiasis.
Rowen JL
Semin Perinatol 2003 Oct;27(5):406-13. doi: 10.1016/s0146-0005(03)00066-1. PMID: 14626505
Congenital candidiasis.
Khambadkone SM, Dixit KM, Divekar A, Joshi SM, Irani SF, Desai M
Indian Pediatr 1996 Jun;33(6):512-6. PMID: 8979616

Diagnosis

Congenital systemic candidiasis: a comprehensive literature review and meta-analysis of 44 cases.
Georgescu TA, Lisievici AC, Munteanu O, Furtunescu FL, Bratu OG, Berceanu C, Bohîlţea RE
Rom J Morphol Embryol 2020 Jul-Sep;61(3):673-680. doi: 10.47162/RJME.61.3.05. PMID: 33817708Free PMC Article
Congenital candidiasis as a subject of research in medicine and human ecology.
Skoczylas MM, Walat A, Kordek A, Loniewska B, Rudnicki J, Maleszka R, Torbé A
Ann Parasitol 2014;60(3):179-89. PMID: 25281815
Congenital candidiasis.
Wang SM, Hsu CH, Chang JH
Pediatr Neonatol 2008 Jun;49(3):94-6. doi: 10.1016/S1875-9572(08)60020-0. PMID: 18947006
Neonatal cutaneous fungal infections.
Smolinski KN, Shah SS, Honig PJ, Yan AC
Curr Opin Pediatr 2005 Aug;17(4):486-93. doi: 10.1097/01.mop.0000171320.91677.55. PMID: 16012261
Mucocutaneous candidiasis.
Rowen JL
Semin Perinatol 2003 Oct;27(5):406-13. doi: 10.1016/s0146-0005(03)00066-1. PMID: 14626505

Therapy

Congenital candidiasis in a full-term infant: A case report.
Zhao HH, Zhe-Zhou, Lu L, Zhao YZ, Yang LJ, Ding YX
J Int Med Res 2023 Apr;51(4):3000605231158015. doi: 10.1177/03000605231158015. PMID: 37062969Free PMC Article
Congenital cutaneous candidiasis associated with maternal peripartum candidemia.
Fernández-Ruiz M, Mosqueda-Peña R, Pérez-Ayala A, Blázquez-Gamero D
Rev Iberoam Micol 2020 Apr-Jun;37(2):68-71. Epub 2020 May 31 doi: 10.1016/j.riam.2020.02.002. PMID: 32493666
Onychodystrophy as the only sign of congenital candidiasis.
Joy Way Bueno SM, Santos Muñoz A, Maldonado I, Larralde M
Pediatr Dermatol 2020 Jan;37(1):159-161. Epub 2019 Oct 20 doi: 10.1111/pde.14021. PMID: 31630427
Neonatal cutaneous fungal infections.
Smolinski KN, Shah SS, Honig PJ, Yan AC
Curr Opin Pediatr 2005 Aug;17(4):486-93. doi: 10.1097/01.mop.0000171320.91677.55. PMID: 16012261
Congenital candidiasis.
Johnson DE, Thompson TR, Ferrieri P
Am J Dis Child 1981 Mar;135(3):273-5. doi: 10.1001/archpedi.1981.02130270065023. PMID: 7211787

Prognosis

Congenital cutaneous candidiasis associated with maternal peripartum candidemia.
Fernández-Ruiz M, Mosqueda-Peña R, Pérez-Ayala A, Blázquez-Gamero D
Rev Iberoam Micol 2020 Apr-Jun;37(2):68-71. Epub 2020 May 31 doi: 10.1016/j.riam.2020.02.002. PMID: 32493666
Early-Onset Invasive Candidiasis in Extremely Low Birth Weight Infants: Perinatal Acquisition Predicts Poor Outcome.
Barton M, Shen A, O'Brien K, Robinson JL, Davies HD, Simpson K, Asztalos E, Langley J, Le Saux N, Sauve R, Synnes A, Tan B, de Repentigny L, Rubin E, Hui C, Kovacs L, Yau YC, Richardson SE; Paediatric Investigators Collaborative Network on Infections in Canada (PICNIC)
Clin Infect Dis 2017 Apr 1;64(7):921-927. doi: 10.1093/cid/cix001. PMID: 28077516
Congenital candidiasis as a subject of research in medicine and human ecology.
Skoczylas MM, Walat A, Kordek A, Loniewska B, Rudnicki J, Maleszka R, Torbé A
Ann Parasitol 2014;60(3):179-89. PMID: 25281815
Congenital candidiasis: a rare and unpredictable disease.
Aldana-Valenzuela C, Morales-Marquec M, Castellanos-Martínez J, Deanda-Gómez M
J Perinatol 2005 Oct;25(10):680-2. doi: 10.1038/sj.jp.7211379. PMID: 16193080
Congenital candidiasis.
Khambadkone SM, Dixit KM, Divekar A, Joshi SM, Irani SF, Desai M
Indian Pediatr 1996 Jun;33(6):512-6. PMID: 8979616

Clinical prediction guides

Congenital systemic candidiasis: a comprehensive literature review and meta-analysis of 44 cases.
Georgescu TA, Lisievici AC, Munteanu O, Furtunescu FL, Bratu OG, Berceanu C, Bohîlţea RE
Rom J Morphol Embryol 2020 Jul-Sep;61(3):673-680. doi: 10.47162/RJME.61.3.05. PMID: 33817708Free PMC Article
Early-Onset Invasive Candidiasis in Extremely Low Birth Weight Infants: Perinatal Acquisition Predicts Poor Outcome.
Barton M, Shen A, O'Brien K, Robinson JL, Davies HD, Simpson K, Asztalos E, Langley J, Le Saux N, Sauve R, Synnes A, Tan B, de Repentigny L, Rubin E, Hui C, Kovacs L, Yau YC, Richardson SE; Paediatric Investigators Collaborative Network on Infections in Canada (PICNIC)
Clin Infect Dis 2017 Apr 1;64(7):921-927. doi: 10.1093/cid/cix001. PMID: 28077516
Congenital candidiasis as a subject of research in medicine and human ecology.
Skoczylas MM, Walat A, Kordek A, Loniewska B, Rudnicki J, Maleszka R, Torbé A
Ann Parasitol 2014;60(3):179-89. PMID: 25281815
Invasive candidiasis in low birth weight preterm infants: risk factors, clinical course and outcome in a prospective multicenter study of cases and their matched controls.
Barton M, O'Brien K, Robinson JL, Davies DH, Simpson K, Asztalos E, Langley JM, Le Saux N, Sauve R, Synnes A, Tan B, de Repentigny L, Rubin E, Hui C, Kovacs L, Richardson SE
BMC Infect Dis 2014 Jun 12;14:327. doi: 10.1186/1471-2334-14-327. PMID: 24924877Free PMC Article
Congenital candidiasis.
Wang SM, Hsu CH, Chang JH
Pediatr Neonatol 2008 Jun;49(3):94-6. doi: 10.1016/S1875-9572(08)60020-0. PMID: 18947006

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